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長期血液透析廔管失能的處置

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813 386

ၡāāࢋ

( Hemodialysis )

( PTA, percutaneous transluminal angioplasty )

ᙯᔣෟĈགྷϩҕგјݭఙ ( Percutaneous transluminal angioplasty, PTA ) ҕ୵౅ژ ( Hemodialysis )

જᐖਔ გεਕ ( Arterio-venous access dysfunction )

݈֏

ॲፂ઼࡚ඪ᝙ঽྤफ़൳ᐂր௚ ( USRDS ) 2006 ѐޘಡӘ޽΍Ă 45 ໐ͽ˯ඪ਽ა߾ඪ۞൴ Ϡத̈́஽Җதέ៉݄ٺБ஧Ă͍׎дέ៉̚ݑొ

гડՀߏځពĄ༊൒߾ඪ გΑਕ۞ள૱Ă˵

ಶՀࠎ೼࿆Ąགྷϩҕგјݭఙ ( PTA, percuta- neous transluminal angioplasty ) ࠎྋՙ߾ඪજᐖ ਔ გεਕ ( Arterio-venous access dysfunction )

૱ϡ۞щБѣड़͞ڱ̝˘

1-4

Ăᔵ൒ѣ̙Тࡊొ۞

ᗁरଂְ఺ีڼᒚ ( Β߁ٸडࡊă͕᝙̰ࡊă͕

᝙γࡊăඪ᝙ࡊඈ )Ăҭ઼̰дԫఙ˯ྵ͌ፋЪ

ّ۞ଣ੅ćώ௡Яѩаᜪ˘ֱ࠹ᙯ͛ᚥ̈́ॲፂ၁ ү۞གྷរĂଂԫఙᆸࢬ˯۞၁ᅫયᗟĂᕩৼፋந ͽ೩ֻણ҂Ă˵ഇ୕ਕΐˢՀкࡁտ׶ਫ਼ᜩĂֽ

൴ण̈́Լซ఺ีԫఙĂͽྋՙ઼̰γᇃ̂߾ඪଈ ۰̝൭ࡴ׶̙ܮĄ

ҕ୵౅ژ ( Hemodialysis ) გεਕ

۞ૄώᄮᙊ

д߉Җ გҕგјݭఙ̝݈Ăυื၆ҕ୵

౅ژ۞ გѣૄώ۞ᄮᙊĂ̖ਕү΍ϒቁ۞ҿ ᕝ̈́఍ཉĂ׎ᖎ̬т˭Ĉ

˘ăܜഇҕ୵౅ژ გ۞჌ᙷĈ

( ˘ )ăҋវ გ ( fistula )Ĉͽঽଈώ֗۞જ ᐖਔҕგүӚЪĂӚЪҜཉ૱֍ٺ͘ඦă͘օ

఍Ăߏͽ፠જਔă۴જਔۡତତЪᐖਔ҃јĄ ( ˟ )ăˠ̍ გ ( graft )ĈѣֱঽଈЯώ֗

ҕგ۞Ч჌Я৵ࢨטĂ̙ዋЪۡତүҋវજᐖਔ

ӚЪఙĂಶืͽˠ̍ҕგүࠎాତ፜ሇֽତЪજ

(2)

ᐖਔâਠˠ̍౅ژ გՄኳࠎ PTFE ( Polyte- trafluoroethylene )Ą

˟ăҕ୵౅ژ გΑਕள૱۞჌ᙷ̈́ҕგব৫ঽ ի۞ΞਕҜཉĈ

ధкېڶົᇆᜩ౅ژ࿅඀۞ึӀซҖ̈́Ԇ јĂкЯҕგგට̝ব৫ٙ࡭Ă૱൴Ϡٺ෹࿅

50% გश۞ব৫

5

Ąҋវҕგ౵ٽдҕ߹ᑅ˧म ព඾۞ҜཉயϠব৫ĂࣧЯֽҋٺᑅमயϠ۞ૻ

˧ҕ߹Ă̙ᕝ኏ᑝҕგጨֹ̰ቯᆧϠ҃யϠব ৫Ą౵૱֍۞ܡ๫ঽիҜཉдҋវٕˠ̍જᐖ ਔ გያܕᐖਔӚЪ఍Ąͽ˭ಶҕ୵౅ژ გ

Αਕள૱۞჌ᙷ̈́׎Ξਕ۞ব৫ঽիҜཉᄲځ

̝Ĉ

( ˘ )ă౅ژॡҲҕ߹ณ ( Low blood flow )

5

Ĉ

ଂତܕજਔӚЪ఍۞ᐖਔҕგ͔΍ҕ߹Ҍ౅ژ፟

ጡĂͽซҖҕ୵౅ژćҭ૱Я٩͔ొҜܕજਔბ

۞ҕგব৫Ăጱ࡭٩͔ҕ߹̙֖Я҃யϠҲҕ߹

ณېڶĂயϠ٩פ੫ྯજன෪่ٕਕͽྵҲҕ߹

ณซҖ౅ژĂֹ౅ژ࿅඀ॡมؼܜٕ̙ԆБ౅ژ ( тဦ˘ )ĄٙͽҲҕ߹ณΞਕ΃ܑд٩͔۞Ҝཉ ܕજਔბѣব৫ঽիĄ

( ˟ )ă౅ژॡ੼ᐖਔᑅ˧ ( High venous pres- sure )

5

Ĉҕ୵གྷ౅ژޢĂ͔ˢߙ఍ᐖਔҕგćЯ ᐖਔҕგব৫ጱ࡭ҕ߹៭᎕Ă൑ڱึၰކࠈĂ౅

ژ፟ጡЯѩពϯᐖਔᑅ˧࿅੼ன෪Ăซ҃አࢫ౅

ژҕ߹߹ณĂ˵ົֹ౅ژ࿅඀ॡมؼܜٕ̙ԆБ

౅ژĄٙͽ౅ژॡពϯ੼ᐖਔᑅ˧Ξਕ΃ܑҕ୵ ڦˢᐖਔ۞ܕ͕ბొҜѣব৫ঽիĄ

( ˬ )ă൑ҕ߹ ( no blood flow )Ĉ൑ҕ߹ېڶ

૱ͽ൑ڱຏᛇਔજ ( pulsation )ăͪ߹ຏ ( thrill )

׶᝘̙זဢᗔࢰ ( bruit ) ֽܑனĂ༊൒౅ژॡಶ

൑ڱ٩͔΍·֖ҕ߹ ( тဦ˟ )ć˘ਠྵ૱֍۞

ଐڶĂА݈̏хд۞ҕგব৫̈́ҕংયᗟĂ൑ኢ ߏ౅ژॡயϠҲҕ߹ณٕ੼ᐖਔᑅ˧ېڶĂޢᜈ

ࡶѣҕংং̄யϠĂटٽдব৫఍யϠܡ๫Ăጱ

࡭ҕ߹ഴٕ̈႖᎕Ă҃ԛјՀкҕং׶ҕ๴Ăซ

҃யϠ გ൑ҕ߹ன෪ĄΩγĂЧ჌ࣧЯֹҕ

߹ഴၙٕயϠ࿅̂ҕংং̄˵ਕౄј გ൑ҕ

߹Ą გ൑ҕ߹఼૱ߏ౵௣ඕڍĂࢋ࿰ീঽի ҜཉͧྵӧᙱĂ఼૱ืАֹϡҕং٩ӛన౯̈́ҕ

ংொੵԫఙΝੵҕং๴યᗟޢĂѣొ̶ҕ߹̖ट ٽͽҕგᛷᇆߤ΍ࣧώব৫ҜཉĂГͽঈ஧ᕖૺ

ඈ͞ڱ఍நব৫ঽիĄ

( α )ă౅ژॡҲҕ߹ณ̈́੼ᐖਔᑅ˧ඈ஄Ъ ݭĈࡗѣˬ̶̝˘ঽଈТॡѣк఍ҕგব৫

2

Ă

ٕயϠॡมѣАޢѨԔĄּтĈѣֱЪ׀Ҳҕ߹

ณ׶੼ᐖਔᑅ˧ېڶćΩѣֱ˘ฟؕ੼ᐖਔᑅ˧

՟ѣ఍நĂޢᜈҕংং̄ጱ࡭൑ҕ߹ېڶĄѣֱ

ঽଈЪ׀ѣк఍Ҝཉ۞ҕგব৫ొҜĂдҕგᛷ ᇆॡពன΍Ăҭ׎АΞਕ่ͽҲҕ߹ณଐԛܑ

னćЯࠎ߹ณ̈ॡĂᑅ˧఼૱̙ົ੼Ăੵܧҕგ ব৫ޝᚑࢦćЯѩ఍ந˞Ҳ߹ณயϠ۞ҕგব৫

ဦ˘Ĉ A Ĉҕგᛷᇆဦϯν݈ᓖҋវજᐖਔ გ̝ᐖ

ਔӚЪব৫఍(቏ᐝ఍)Ą

BĈҕგᛷᇆဦϯགྷ გјݭఙޢᐖਔӚЪব৫

఍გට̂̈̏ځពԼච(቏ᐝ఍)Ą

B

A

(3)

યᗟޢĂᑕڦຍߏӎѣЪ׀ѣ׎΁Ҝཉ۞ব৫ঽ իĄ

( ̣ )ă౅ژٕ̚౅ژޢѣ͘ᓖཚ൭াېĈ˘

ਠ౵૱൴Ϡд̚δᐖਔҕგܡ๫ॡĂ׎૱Яཉˢ Чᙷጱგ͔҃੓ć̚δᐖਔҕგܡ๫ጱ࡭౅ژॡ а߹צܡĂ̙ည׹ᙝব৫ҕგــѣ׎΁઎͚ҕ

გΞ͔߹Ăซֹ҃ᐖਔᑅᆧ੼͔҃੓͘ᓖཚ൭Ą ҭ൑াې۞̚δᐖਔҕგব৫̙֭ื఍ཉ

6

Ą

გҕგјݭఙ۞ఙ݈໤౯Ĉ

გјݭఙ࠹၆ٺ͘ఙڼᒚ۞р఍дٺܬ ˢّྵ̈ăఙޢূ൭̈ăΞܲ঻ᐖਔҕგ̈́̚δ ᐖਔҕგ˵Ξ఍ཉඈĄ׎ఙ݈۞໤౯̍үт˭Ĉ

˘ă͕࿪ဦăҕგᑅ˧̈́ײӛېڶႾീĈ

˘ਠጱგވ౯ѣ۞͕࿪ဦăҕგᑅ˧ăײӛ ېڶ۞ႾീᆇጡืְА౯ԁĂͽүࠎঽˠېڶă ঽի఍ཉ݈ޢෞҤ׶ѣ൑׀൴াඈႾീ̝ϡĄ

˟ăঽիҜཉ۞࿰ീ̈́ᕚҜĈ

ֶፂঽΫ׶நጯᑭߤֽෞҤ࿰ീঽիΞਕҜ ཉ

7

Ă༊൒˵Ξͽౌ˪ઙ෹ࢰگםӄؠҜĂຐؠ ڼᒚඉர֭ͷՙؠგᐘཉˢҜཉ̝ޢĂ૟ଈ઎͘

ᓖүዋ༊ᕚҜĂ͞ܮࡍו̈́ཉˢგᐘĄ ˬăА݈ᘽۏ۞໤౯Ĉ

( ˘ )ă౫ዕᄃͤ൭ĈΞֹϡ Midazolam ٕ Fentanyl үࠎ౫ዕͤ൭̝ϡ

8

ćώ͕̚ϫ݈Ᏼϡ Fentanyl ࡗ 1 Ҍ 2 cc ( 50 ɢ g/cc ) ᐖਔග̟Ăͽഴ

͌ঽଈఙ̚۞൏ᇋ׶ূ൭Ą͍׎дঈ஧ᕖૺјݭ ఙॡĂΞځពഴᅅঽˠ۞ূ൭޽ᇴĄืႾീঽˠ

۞ײӛېڶĄ

( ˟ )ăԩ጖ҕ጗Ĉ࿰ഇ఍ཉ࿅඀።ॡົྵ

˳ăঽիᇴྵкٕҕং๴ྵкଈ۰Ăֹϡ u n - fractionated heparin ׶ low molecular weight heparin ͽഇ୕ࢫҲఙ̚ҕংԛј۞፟ົĂҭ̙ืՏ࣎ঽ

ּ࠰૱ఢֹϡ

5

Ą

( ˬ )ăҕং໘ྋ጗Ĉ၆ٺಱӣҕგҕং۞ঽ իĂֹϡҕং໘ྋ጗ߏഴ͌ҕং۞͞ڱ̝˘Ăּ

т Urokinase Ă˵ื҂ᇋ΍ҕ۞ઘүϡ

9,10

Ą

ጱგგᐘ ( sheath ) ̂̈ܜޘăཉˢ Ҝཉ̈́͞Ш۞ᏴፄĈ

˘ăጱგგᐘ̂̈׶ܜޘ۞ᏴፄĈ

( ˘ )ăგश̂̈Ĉ˘ਠᄃ გεਕ۞ࣧЯă ঽիҜཉă࿰౯Ꮾਖ਼۞ጡୠ̂̈ăڼᒚ۞ඉரᄃ ϫᇾѣᙯĄᓝּᄲځĈҋវજᐖਔ გЯҲҕ߹

ณ۞ଈ۰Ă૱ߏӚЪ఍ᐖਔბѣব৫ٙ࡭Ă׎ણ

҂გටგश˘ਠྵ̈ĂΞֹϡྵ̈ঈ஧ĂٙͽΞ ϡྵ̈۞გᐘ ( т 6 French )ĄΩγĂЯᐖਔব̈

ဦ˟Ĉ A Ĉҕგᛷᇆဦϯν݈ᓖˠ̍જᐖ გԆБܡ

๫׀ѣҕং(቏ᐝ఍)Ą

BĈҕგᛷᇆဦϯν݈ᓖˠ̍જᐖ გགྷ გј ݭ ఙ ޢ ࢦ ޙ ҕ ߹ Ă ̪ ׀ ѣ ണ ঻ ҕ ং ( ቏ ᐝ

఍)Ą

B

A

(4)

ጱ࡭۞౅ژॡᑅ˧੼ٕঽիЪ׀ҕংҕ๴Ă҂ᇋ

ֹϡ٩ӛన౯ٕጡୠॡâਠౌົᏴϡྵ̂۞გ ᐘ ( 7-8 French )Ă༊൒გᐘດ̂Ăޢᜈಶດ̙ٽ

ͤҕĄֶ࣎ˠགྷរĂ 7 French გᐘಶ֖ૉ఍ந̂

ొ̶۞ঽիĄ

( ˟ )ăგᐘܜޘĈᚑॾֽᄲĂᑕߏཉˢҕგ

۞ܜޘĂЯࠎ˘ਠ֭Ϗ૟გᐘБొܜޘཉˢҕგ

̚ ( 7 Ƃ 10 cm )Ă҃ߏ঻˘߱ܜޘдγć఺ᆃઇ

۞ϫ۞дٺѣॡࣧ౅ژࡍוҜཉᄃঽի෼ᗓѣ ࢨĂื࿰঻఍ཉ۩มĂтঈ஧۞ᕖૺඈĂ༊൒ѣ ॡࡍוҜཉᄃঽի࠹ᗓޝᅈĂੵপঅ҂ᇋγĂಶ Ξ૟გᐘБొཉˢĄ

˟ăጱგგᐘཉˢҜཉ۞ᏴፄĈ

ᐌ඾ঽի۞ΞਕҜཉ̈́Ч჌̙Т۞ڼᒚඉ ரĂົᏴؠ̙Т۞გᐘཉˢҜཉâਠͽࣧА౅

ژࡍוҜཉࠎᐹАᏴፄćЯࠎྍҜཉྵਕͅߍ౅

ژॡ۞၁ᅫ გεਕېڶĂ͞ܮޢᜈ఍நĄּ

тĈࣧ౅ژࡍוҜཉ٩͔ҕ߹ณ̙֖ĂΞਕܑϯ дҕ߹˯ഫҜཉѣব৫ঽիĂϤࣧࡍוҜཉਗ਼඾

ҕ߹͞ШཉˢგᐘĂ֭ͷื࿰঻გᐘ౤ბᄃঽի มֱధ෼ᗓĂܮਕᖎಏг෧ᕝͷڼᒚঽիĄ ˬăጱგგᐘཉˢ͞Ш۞ᏴፄĈ

( ˘ )ăგᐘ͞ШົЯ඾ঽի׶გᐘ࠹ᙯҜཉ

̈́ڼᒚඉர҃ѣ̙ٙТĂֶҕ߹͞Ш̶ࠎึ߹

( antegrade ) ׶ਗ਼߹ ( retrograde ) ͞Шć׎मள͹

ࢋдҕგᛷᇆ෧ᕝॡĂᄲځт˭Ĉ

1 ăึ߹͞ШĈϤგᐘڦडពᇆ጗ᛷᇆĂព ᇆ጗ึ߹҃˭ĂۡତΞ֍˭ഫঽիćҭგᐘ۞˯

ഫঽիΞਕЯពᇆ጗Ш˭ഫଵᗓĂ҃൑ڱពϯ΍

ѣ൑ঽիĄѩॡΞд˭ഫ͔߹ᐖਔ૟ঈ஧ᕖૺٕ

ᑅ࢝ĂТॡڦडពᇆ጗࡭ਗ਼߹ז˯ഫ఍ֽពϯѣ

൑ঽիĂಶ̙ืЯѩГཉˢΩ˘გᐘĄ

2 ăਗ਼߹͞ШĈϤგᐘڦडពᇆ጗Яҕ߹ਗ਼

߹Я৵Ăдঽի෼ᗓგᐘྵܕĂٕдҕ߹ณ̈( Ϗ

఍ཉॡ) ٕϡ˧ڦडពᇆ጗ॡĂٕధΞពϯ΍˯ഫ ঽիćҭҕ߹ณ̂ॡ ( ܡ๫̙ᚑࢦٕ఍ཉޢ )ĂϤ ٺ֝ిଵᗓពᇆ጗Ă࡭ѣॡ൑ڱෞҤ˯ഫঽիĄ ѩॡΞֹϡጱቢ૟ጱგ ( ּтĈ Judkin's right catheter ) Ҍତܕঽի఍ĂϤጱგ̰ڦडពᇆ጗ֽ

ෞҤ˯ഫঽիĄ

( ˟ )ăᖎ҃֏̝Ăგᐘ͞Шᓁߏࢋ၆඾ঽ

իĂ͞ਕ఍நঽիĂ఺ߏ౵Аࢋ҂ᇋ۞ćҌٺҕ გᛷᇆ෧ᕝ˯Ă൑ኢึ߹ٕਗ਼߹͞ШĂᖣϤঈ஧

ᕖૺăᑅ࢝ҕგ̈́ጱგ۞ֹϡ׶ᑕϡĂౌΞҹڇ ҕგᛷᇆ෧ᕝ˯۞̙֖Ą

αăӧᙱጱგგᐘ۞ཉˢĈ

( ˘ )ăҕგ̚ࡶѣҕ߹ĂдࡍוॡΞགྷϤа ҕቁᄮдҕგට̚ćҭࡶ൑ҕ߹ॡĂࢋቁᄮࡍו ˢҕგට̚Ăಶߏ˘࣎ࢦࢋ۞Վូ׶ᙯᔣĄͽ˭

೩΍࣎ˠֹϡ۞ೀ࣎͞ڱֻણ҂Ĉ

1 ăࡍוॡ͘ຏĈ͍׎૱дࡍוˠ̍ გĂ ࡍו੫ซˢॡຏזҕგܡ˧ࡎ൒гঐεĂ̙࿅఺

ื੨Ъ׎΁͞ڱГቁᄮĂಏϡѩڱ̙֭ޝΞያĄ 2 ă޽͔ጱቢ۞֕ШĈซˢ޽͔ጱቢึၰ൑

ܡ˧ͷ׶ გ۞֕Ш˘࡭ĂՀΞቁᄮдგට̚Ą 3 ă࢑ᑅ٩ӛĈѣॡֹϡ 10cc ۩੫࢑ᑅ٩ӛ

͞ёΞਕົѣֱధаҕĂ͍׎дϏԆБܡ๫۞ঽ

ּĂΞͽᑀྏѩ͞ڱĄ

4 ă͌ณពᇆ጗ീྏĈΞͽଂࡍו੫ڦड͌

ณពᇆ጗Ăֽቁᄮߏӎдҕგට̚Ăҭ͉кពᇆ

጗ѣॡົᜨ΍ҕგĂซ҃ᇆᜩҿᕝĄ

5 ăՀೱࡍוҜཉĈЯࠎંටԛјĂࡍו֎

ޘᄃҕგ֕ШඈЯ৵ĂѣॡืՀೱࡍוҜཉĂ͍

׎Ᏼፄજਔბٕያܕਔજ۞Ҝཉࡍו

11

ĂΞϤа ҕቁᄮĂࡍוҋ൒ྵटٽјΑĄ

გҕგјݭఙ̝఍ཉ

გҕგјݭఙٕ͘ఙ۞ϫ۞дΝੵҕგඕ ၹّត̼Ăซ҃ޭೇ׎౅ژΑਕĂᄲځт˭Ĉ

˘ăҕგјݭఙన౯ăጡୠ׶̍׍ ( тဦˬ ) ̈́

׎ԫఙ

( ˘ ) ăጱ͔ጱቢĈώ͕̚ϫֹ݈ϡ 0 . 0 3 5

Fr ă( 0.89 ୮Ѽ௖௟ ) /150 ̶̳ܜޘጱ͔ጱቢĂϤ

ဦˬĈဦϯ გјݭఙ૱ϡ̝ጡୠĂΒ߁გᐘ(ӣგᐘ ጱቢ̈́ᇣฟგ) ăጱቢăᕖૺঈ஧ጱგ̈́·ঈన ౯Ą

(5)

͟ώ Te r u m o ̳ΦϠயĂೀͼౌΞึӀ఼࿅ঽ իĄ

( ˟ )ăঈ஧ᕖૺր௚ĈᖣϤ፟ୠّ۞ᑟᑅ̈́

ᇧෘᆧϠ̰ቯٕҕংĂͽᆧΐব৫఍გට̰शĂ

҃ྋՙЯҕგব৫͔੓Ч჌ გεਕ۞યᗟćϫ

ֹ݈ϡ fox plus ( Abbott ̳ΦϠய ) ׶ ATB AD- VANCE ( COOK ̳ΦϠய ) ׌჌׹ᙝҕგ۞ঈ஧ᕖ

ૺր௚Ăᓁܜ 80 cm Ăঈ஧ܜޘࠎ 40 mm Ăঈ஧̂

ֶ̈ঽիᏴؠâਠଂ 5 Ҍ 12 mm Ăдฉᙝᐖਔ

׶ˠ̍ҕგ૱ϡ 5 Ƃ 8 mm Ă̚δᐖਔ૱ϡ 9 Ƃ 12 m m ĄҌٺᕖૺᑅ˧ᐌঽիব৫ർޘ̙̂̈҃

Тâਠ૱ϡ 4 Ҍ 20 atm Ąࡶ̪൑ڱԆБᕖૺฟ

۞͌ᇴ࿱ԩّঽիĂΞֹϡ੼ᑅᕖૺঈ஧̷ٕ౷

ঈ஧఍ந

12-15

Ą

( ˬ )ăҕგ͚ߛ ( stent )Ĉ၆ٺঈ஧ᕖૺޢа ᇅّঽիĂٕൺഇ̰ ( ˬ̰࣎͡ ) ͅᖬгГܡ๫

̈́̚δᐖਔܡ๫ҜཉĂҕგ͚ߛཉٸߏ˘ีڼᒚ ᏴፄĂ̪ื҂ᇋঽիҜཉĂ̂̈׶ܜൺ̈́ߏӎᇆ ᜩޢᜈ͘ఙඈયᗟĂᐌ඾ࡁտᏴפ۞୉ཏѣ̙Т

۞ᓜԖඕڍĂߏӎѣр఍̪൒ѣۋᛉ

16,17

Ą ( α )ăҕং٩ӛన౯̈́ҕংொੵԫఙĈ д఍ந൑ҕ߹ঽּॡĂொੵҕং૱ߏ఍ந࿅

඀۞ௐ˘ՎូĂҕংொੵѣొ̶ҕ߹ޢĂ˵̖ਕ ତᜈ෧ᕝ֭఍ந׎΁ব৫ঽիĄ

1 ă࢑ᑅ٩ӛր௚Ĉֶனѣጡୠ૟ጱ͔ጱგ ( ˘ਠϡ 6 Fr ă Judkin's right guiding catheter ) ੨

˯̏٩ 10 ୮̿ࢴៃͪ۞ 50 ୮̿੫ඌĂ૟ጱ͔ጱ გਖ਼Ҍҕგҕং఍Ăͽ࢑ᑅ٩ӛҕং

18

Ą

2 ă͛ᚥ൴ܑ۞٩ӛր௚నࢍĈࠎொੵҕং๴

֭ᔖҺ࿅кҕং߹Ҍ۱ҕგĂԛј۱ং๫âֱ

͛ᚥಡጱֹϡপҾనࢍ۞٩ӛր௚ֽ྿זѩϫĂ

൴ܑ׎ड़ڍព඾

19,20

Ąώ͕̚ϫ݈੫၆ᇴ჌͞ڱϒ ซҖෞҤࡁտĂഇ୕ӀϡனѣΞ଀۞ጡୠĂ൴ण ѣड़۞͞ڱֽொੵҕং׶ᔖҺ۱ং๫׀൴াĄ

˟ăјΑத̈́ҕ୵౅ژ გΑਕ۞Гள૱Ĉ

͘ఙјΑதࡗ 80-98%

1,8,21-23

Ąҭ გεਕࣧ

ώಶхдЧ჌۞ΐࢦЯ৵Ă఍ཉޢ౅ژΑਕ۞ޭ

ೇ֭൑ڱ૟఺ֱЯ৵ԆБΝੵĂּтજᐖਔӚЪ ๕υѣព඾۞ᑅ˧मхдĂౄјૻ̂۞ҕ߹኏ᑝ

׶̰ቯ۞൴ۆன෪ĂΩγҕংԛј۞યᗟඈ˘ۡ

ౌົхдĂЯѩܜᅈֽᄲ გ۞Гεਕத༊൒

ޝ੼Ą˘ѨјݭఙπӮࡗჯ޺̱࣎͡Ăࡶˬ࣎͡

̰ืઇ׌Ѩјݭఙͽ˯Ăಶޙᛉ͘ఙڼᒚ

5

Ą ˬăγࡊ͘ఙ̬ˢĈ

ࡶ൑ڱᖣϤҕგјݭఙඈ͞ڱޭೇ׎ҕგ౅

ژΑਕॡĂಶื҂ᇋͽγࡊ͘ఙ̬ˢ͞ё఍நĂ

ּтĂᏴፄΩ˘఍үҕგӚЪ͘ఙĄ

ҕგјݭఙ݈ޢ۞ෞҤ

ҕგܡ๫ঽի۞ෞҤĂੵ˞౵ૄώ۞ҕგᛷ ᇆᇆညγĂ׎΁ѣధк۞͞ڱϺΞϡֽෞҤߏӎ ࠎѣຍཌྷ۞ঽի҃ืү఍ཉĂ҃఍ཉ۞ϫᇾͽޭ

ೇ გ۞౅ژΑਕࠎ͹Ă̙֭҃ߏͽ "ҕგ۞ፋ ԛ" ࠎϫᇾĂΞߏ఍ཉ̙ԆБϺߏ გГεਕ۞

ࣧЯ̝˘Ăͽ˭೩ֻᇴ࣎ෞҤ͞ڱүࠎણ҂Ăᑕ ტЪᑕϡĈ

˘ăҕგგशഴ̈Ă఍ཉޢᆧΐĈڦडពᇆ

጗ॡᛷᇆࡶҕგგशͧણ҂शځពഴ̈Ă͍׎Ъ

׀ѣҕ߹߹ిၙଐԛॡĂྍঽիᑕߏѣຍཌྷ۞ব ৫ঽիĄ఍ཉޢҕგგशᑕᆧΐͷ౺ዶܡ๫̈ٺ 30% Ă̖ߏѣड़఍ཉ

5

Ą

˟ăҕ߹߹ిഴၙĂ఍ཉޢᆧԣĈѣຍཌྷ۞

ব৫ঽիĂ૱࡭ҕ߹߹ిតၙĂࡶ߉χពᇆ጗۞

጗ณ̈́˧྽࠹༊ĂΞϡᛷᇆૺᇴ ( frame counts )

ࢍზពᇆ጗۞ଵੵֽෞҤ̈́ؠณҕ߹ిć༊൒ૺ

ᇴ෸кಶពϯҕ߹෸ၙĄܡ๫ٕব৫ঽի఍ந ޢĂҕ߹߹ిᑕតԣĂᛷᇆॡពᇆ጗ޝԣజଵ

ੵĂϤѩ˵Ξۢ఍ཉड़ڍрᗼĄ

ˬăҕგব৫఍׌઎ᑅ˧मᆧΐĂ఍ཉޢഴ

̈Ĉҕ߹఼࿅ҕგব৫఍ॡĂҕგ۞ܡ˧ᆧΐĂ ᑅ˧मᐌ̝ᆧΐĂЯѩব৫ঽի׌ბ۞ᑅ˧मΞ

ͅߍ΍ঽի۞ব৫඀ޘĄЯࠎ გ૱ԛјҕგ ሳĂֹҕგણ҂श̙ٽෞҤĂΞᖣϤব৫఍ᑅ˧

मԼត۞ณ̼͞ڱĂֽෞҤߏӎࠎѣຍཌྷ۞ব৫ ঽիĄব৫ঽի఍நޢĂব৫఍გशត̂Ăܡ˧

ត̈Ăᑅ˧मซ҃ഴ̈Ăҕ߹ᐌ̝ᆧΐĄ αă׎΁઎͚ᐖਔ͔߹ҕგᆧΐĂ఍ཉޢഴ

ٕ͌ঐεĈܡ๫۞ҕგጱ࡭͔߹ᐖਔᑅ˧ᆧΐĂ а߹ᐖਔᑅ˧ᆧΐĂֹ׎͔ˢ׎΁ᑅ˧ྵ̈ᐖਔ ҕგ̚ĂயϠధк͔߹۞઎͚̈ҕგតځពĂ఺

˵ߏҕგব৫ٕܡ๫۞ᇈЏĄܡ๫ٕব৫ঽի఍

நޢĂЯࠎҕ߹͔߹ᑅ˧ഴ̈Ă׎΁ᚮۋّҕგ

(6)

׶઎͚ೈᒖҕგᑅ˧࠹၆ྵ੼ॡĂҋ൒ົഴٕ͌

ঐεĄ

̣ăҕ߹ຏ ( thrill ) ̈́ဢᗔࢰ ( bruit ) ഴ̈Ă఍

ཉޢ΍னٕᆧΐĈ఺׌࣎ᇈЏͅߍ˞ҕ߹ి ( ณ ) ېڶĂࡶѣҕგব৫ᇆᜩҕ߹ॡĂѩ׌ᇈЏҋ൒

ഴ̈Ąܡ๫ٕব৫ঽի఍நޢĂҕ߹ᆧΐѩᇈЏ ಶົ΍னٕᆧΐĄ

̱ăౌ˪ઙ෹ࢰگĈͽҕგব৫யϠᑅ˧म

۞៍هĂϡౌ˪ઙ͞ڱֽؠҜҕგব৫ొҜĂࠤ ҌෞҤব৫۞ᚑࢦޘĂΞүࠎঽիؠҜ׶݈ޢෞ

Ҥ၆໰۞˘჌͞ڱĄ

׀൴া̈́ఙޢڦຍְี

ᓁ൴Ϡதࡗࠎ 1.15%

24

Ă૱֍׀൴াт˭Ĉ

˘ăᐖਔҕგ৔ෘĈѣࡁտ௚ࢍ൴Ϡதࡗ 0.9%

25

âਠ̶ࠎฉᙝݭ̈́̚δݭĂฉᙝݭͧྵ

टٽϡᑅֽ࢝ͤҕĂҭЯᄃજਔ࠹ତĂѣॡЯҕ გᑅ˧̂ົౄјᚑࢦҕཚĂࠤҌටވা࣏ཏĂಶ ᅮࢋγࡊ͘ఙ̬ˢڼᒚĄ̚δݭҕგ৔ෘĂ݋Я

൑ڱͽΐᑅֽͤҕâό൴Ϡᐖਔҕგ৔ෘĂ૱

ืࢋ͘ఙ̬ˢĂ߇఍ཉ˯ื˧ՐщБͷ࠹၆ܲч

ֱĄ

˟ăጱგგᐘཉˢ఍΍ҕ̈́ҕཚ

26

Ĉдგᐘ ཉˢॡĂ͍׎ߏ൑ҕ߹ېڶĂЯࠎࡍוॡྵᙱቁ ᄮдҕგට̚Ăጱ࡭ٽѣ΍ҕ׶ҕཚன෪யϠĂ

ֹϡԩ጖ҕ጗׶ҕং໘ྋ጗̈́ࢦᒔҕ߹ॡĂՀٽ

൴ϠĄ

ˬăާّҕংயϠĈ̙ኢߏ͘ఙ۞࿅඀ٕߏ ޢᜈͤҕᑅ࢝࿅ޘĂౌѣΞਕԛјާّҕংĂ҃

ᇆᜩҕ߹ĂҭּҖֹϡ Heparin ٕ low molecular weight heparin ߏӎΞѣड़࿰֨ާّҕং̪ѣޞ ซ˘ՎࡁտĂ Urokinase ݋ѣಡӘពϯΞѣड़ϡ

ֽڼᒚҕং׶۱ং๫۞׀൴া

9,10

Ą

αă۱ং๫Ĉѣֱࡁտ޽΍јݭఙ࿅඀Ξਕົ

யϠ۱ং๫Ăᓂֹ̂кᇴߏ൑াېٕ̙ᚑࢦ

27

Ăಶ ώ͕̚ϫ݈གྷរĂ˵֭൑ঽּѣځពাې҃ᅮࢋ

ڼᒚĂٕధЯࠎҕংณ̙к̈́۱ొ၆͌ณҕং۞

࡝צّඈࣧЯĄҭ఍ந࿅඀̚Ăቁ၁ົѣҕংа

߹Ҍ۱ొଐڶâ͞ࢬԧࣇనڱԼචԫఙͽഴ͌

ҕংং๫ଐԛâ͞ࢬԧࣇ˵ϒࡁտϡЧ჌͞ڱ

ֽෞҤ׎ᓜԖ۞ࢦࢋّĄ

̣ăֹϡ౫ዕͤ൭ঽଈĂᑕ͕̈៍၅ෞҤຍ ᙊېڶĂຍᙊԆБޭೇٕछᛳౖТ˭ؕΞᗓੰĂ ͽҺ̚౉൴ϠПᐍĄ

ඕኢ

Яᑕ߾ඪˠ˾̈́౅ژ გεਕঽּ۞ᆧ ΐĂдଈ۰ѣࢨ۞ҋវҕგᇴϫ݈೩˭Ăтңͽ ҕგјݭఙޭೇ გ۞ΑਕĂ֭ᔖҺঐਈҋវ ҕგ׶ӚЪ͘ఙ۞൭ࡴĂЯѩ൴ण׶Լซҕგј ݭఙѣ׎υࢋّĂҭ୕ЧҜᗁጯАซТрࣇ̙ӊ

޽ϔ́ଣ੅఺͟ᔌࢦࢋ۞ኝᗟĄ

ણ҂͛ᚥ

1.Beathard GA. Percutaneous transvenous angioplasty in the treat- ment of vascular access stenosis. Kidney Int 1992; 42: 1390-7.

2.Kanterman RY, Vesely TM, Pilgram TK, Guy BW, Windus DW, Picus D. Dialysis access grafts: anatomic location of venous stenosis and results of angioplasty. Radiology 1995; 195: 135- 9.

3.Gray RJ. Percutaneous intervention for permanent hemodialy- sis access: a review. J Vasc Interv Radiol 1997; 8: 313-27.

4.Vesely TM. Percutaneous transluminal angioplasty for the treat- ment of failing hemodialysis grafts and fistulae. Semin Dial 1998; 11: 351.

5.K/DOQI Clinical Practice Guidelines and Clinical Practice Recommendations 2006 Updates Hemodialysis adequacy Peritoneal Dialysis Adequacy Vascular Access. Am J Kidney Dis 2006; 48(Suppl 1): S1.

6.Levit RD, Cohen RM, Kwak A, et al. Asymptomatic central ve- nous stenosis in hemodialysis patients. Radiology 2006; 238:

1051-6.

7.Beathard GA. Physical examination of the dialysis vascular ac- cess. Semin Dial 1998; 11: 231.

8.Beathard GA. Angioplasty for arteriovenous grafts and fistulae.

Semin Nephrol 2002; 22: 202-10.

9.Greenberg RK, Ouriel K, Srivastava S, et al. Mechanical versus chemical thrombolysis: an in vitro differentiation of throm- bolytic mechanisms. J Vasc Interv Radiol 2000; 11: 199-205.

10.Kinney TB, Valji K, Rose SC, et al. Pulmonary embolism from pulse-spray pharmacomechanical thrombolysis of clotted hemodialysis grafts: urokinase versus heparinized saline. J Vasc Interv Radiol 2000; 11: 1143-52.

11.Manninen HI, Kaukanen ET, Ikaheimo R, et al. Brachial arteri- al access: endovascular treatment of failing Brescia-Cimino hemodialysis fistulas-initial success and long-term results.

Radiology 2001; 218: 711-8.

12.Trerotola SO, Stavropoulos SW, Shlansky-Goldberg R, Tuite

CM, Kobrin S, Rudnick MR. Hemodialysis-related venous

stenosis: treatment with ultrahigh-pressure angioplasty bal-

(7)

loons. Radiology 2004; 231: 259-62.

13.Trerotola SO, Kwak A, Clark TW, et al. Prospective study of balloon inflation pressures and other technical aspects of hemodialysis access angioplasty. J Vasc Interv Radiol 2005; 16:

1613-8.

14.Vesely TM, Siegel JB. Use of the peripheral cutting balloon to treat hemodialysis-related stenoses. J Vasc Interv Radiol 2005;

16: 1593-603.

15.Carrafiello G, Lagana D, Mangini M, et al. Cutting Balloon an- gioplasty for the treatment of haemodyalisis vascular accesses:

midterm results. Radiol Med (Torino) 2006; 111: 724-32.

16.Turmel-Rodrigues L, Pengloan J, Baudin S, et al. Treatment of stenosis and thrombosis in haemodialysis fistulas and grafts by interventional radiology. Nephrol Dial Transplant 2000; 15:

2029-36.

17.Bakken AM, Protack CD, Saad WE, Lee DE, Waldman DL, Davies MG. Long-term outcomes of primary angioplasty and primary stenting of central venous stenosis in hemodialysis pa- tients. J Vasc Surg 2007; 45: 776-83.

18.Turmel-Rodrigues L, Raynaud A, Louail B, Beyssen B, Sapoval M. Manual catheter-directed aspiration and other thrombecto- my techniques for declotting native fistulas for hemodialysis. J Vasc Interv Radiol 2001; 12: 1365-71.

19.Horita Y, Namura M, Matsumura M. Development of a novel catheter preventing the outflow of debris and thrombus on per- cutaneous transluminal angioplasty for hemodialysis access fis- tulas. Catheter Cardiovasc Interv 2006; 67: 961-6.

20.Strauss EB, Delman BN, Maitem A. A rapid low-cost uncrossed sheath method for clearing thrombosed hemodialysis grafts. A- JR 2001; 177: 317-8.

21.Glanz S, Gordon DH, Butt KM, Hong J, Lipkowitz GS. The role of percutaneous angioplasty in the management of chronic hemodialysis fistulas. Ann Surg 1987; 206: 777-81.

22.Hunter DW, So SK. Dialysis access: Radiographic evaluation and management. Radiol Clin North Am 1987; 25: 249-60.

23.Safa AA, Valji K, Roberts AC, Ziegler TW, Hye RJ, Oglevie SB.

Detection and treatment of dysfunctional hemodialysis access grafts: Effect of a surveillance program on graft patency and in- cidence of thrombosis. Radiology 1996; 199: 653-7.

24.Sacks D, McClenny TE, Cardella JF, Lewis CA. Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol 2003; 14: S199-202.

25.Beathard GA, Litchfield T, Physician Operators Forum of RMS Lifeline, Inc. Effectiveness and safety of dialysis vascular ac- cess procedures performed by interventional nephrologists.

Kidney Int 2004; 66: 1622-32.

26.Beathard GA. Management of complications of endovascular dialysis access procedures. Semin Dial 2003; 16: 309-13.

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Pulmonary embolism following hemodialysis access thrombol-

ysis/thrombectomy. J Vasc Interv Radiol 1995; 6: 683-6.

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Management of Hemodialysis Access Dysfunction

Chi-Cheng Lai

1

, Tung-Cheng Yeh

1

, Chun-Yao Lin

1

, Chih-Yang, Hsu

2

, Shih-Hung Hsiao

1

, Guang-Yuan Mar

1

, and Chun-Peng Liu

1

As the number of patients undergoing hemodialysis in Taiwan increases, the same increment has also been observed in the incidence of hemodialysis access dysfunction and this has lead to a demonstration of signifi- cance of the role of percutaneous transluminal angioplasty (PTA) in these lesions. After a review of the present literature along with a collaboration of our experience in angioplasty, we integrated and organized present data to serve as a clinical reference for other clinicians. In this review, we introduce the topics such as the basic con- cepts on arteriovenous access, types and sites of arteriovenous access dysfunction, prediction of sites of dys- function, preparations of puncture sites, directions and position of sheaths, options of angioplastic devices, meth- ods for evaluation of lesions before and after PTA along with their related complications. We hope that more physi- cians engage in studies and attempts to alleviate pain and inconvenience of patients undergoing hemodialysis.

( J Intern Med Taiwan 2008; 19: 197-204 )

1

Cardiovascular Medical Center,

2

Division of Nephrology, Department of Internal Medicine,

Kaohsiung Veterans General Hospital

參考文獻

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