陸、參考文獻
al-Sereiti, M. R., K. M. Abu-Amer, et al. (1999). "Pharmacology of rosemary (Rosmarinus officinalis Linn.) and its therapeutic potentials."
Indian J Exp Biol 37(2): 124-30.
Amalinei, C., I. D. Caruntu, et al. (2007). "Biology of metalloproteinases." Rom J Morphol Embryol 48(4): 323-34.
Banno, N., T. Akihisa, et al. (2004). "Triterpene acids from the leaves of Perilla frutescens and their anti-inflammatory and antitumor-promoting effects." Biosci Biotechnol Biochem 68(1): 85-90.
Brown, L. F., M. Detmar, et al. (1997). "Vascular permeability
factor/vascular endothelial growth factor: a multifunctional angiogenic cytokine." Exs 79: 233-69.
Byrne, A. M., D. J. Bouchier-Hayes, et al. (2005). "Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF)." J Cell Mol Med 9(4): 777-94.
Carmeliet, P., N. Mackman, et al. (1996). "Role of tissue factor in embryonic blood vessel development." Nature 383(6595): 73-5.
Chung, T. W., S. K. Moon, et al. (2004). "Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells:
complete regression of hepatoma growth and metastasis by dual mechanism." Faseb J 18(14): 1670-81.
Cristofanilli, M., C. Charnsangavej, et al. (2002). "Angiogenesis
modulation in cancer research: novel clinical approaches." Nat Rev Drug Discov 1(6): 415-26.
Denekamp, J. (1984). "Vascular endothelium as the vulnerable element
in tumours." Acta Radiol Oncol 23(4): 217-25.
Drake, C. J., A. LaRue, et al. (2000). "VEGF regulates cell behavior during vasculogenesis." Dev Biol 224(2): 178-88.
Eom, K. S., J. M. Hong, et al. (2008). "Berberine induces G1 arrest and apoptosis in human glioblastoma T98G cells through
mitochondrial/caspases pathway." Biol Pharm Bull 31(4): 558-62.
Esser, S., M. G. Lampugnani, et al. (1998). "Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells." J Cell Sci 111 ( Pt 13): 1853-65.
Fang, X., R. C. Chang, et al. (2005). "Immune modulatory effects of Prunella vulgaris L." Int J Mol Med 15(3): 491-6.
Fidler, I. J. (2002). "The organ microenvironment and cancer metastasis."
Differentiation 70(9-10): 498-505.
Folberg, R., V. Rummelt, et al. (1993). "The prognostic value of tumor blood vessel morphology in primary uveal melanoma." Ophthalmology 100(9): 1389-98.
Fukamiya, N., M. Okano, et al. (1992). "Antitumor agents, 127.
Bruceoside C, a new cytotoxic quassinoid glucoside, and related compounds from Brucea javanica." J Nat Prod 55(4): 468-75.
Gomaa, A. I., S. A. Khan, et al. (2008). "Hepatocellular carcinoma:
Epidemiology, risk factors and pathogenesis." World J Gastroenterol 14(27): 4300-8.
Grondahl-Hansen, J., I. J. Christensen, et al. (1993). "High levels of urokinase-type plasminogen activator and its inhibitor PAI-1 in cytosolic extracts of breast carcinomas are associated with poor prognosis." Cancer Res 53(11): 2513-21.
Hillen, F. and A. W. Griffioen (2007). "Tumour vascularization:
sprouting angiogenesis and beyond." Cancer Metastasis Rev 26(3-4):
489-502.
Houck, K. A., N. Ferrara, et al. (1991). "The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA." Mol Endocrinol 5(12):
1806-14.
Houck, K. A., D. W. Leung, et al. (1992). "Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms." J Biol Chem 267(36): 26031-7.
Hsu, Y. L., P. L. Kuo, et al. (2008). "Huang-lian-jie-du-tang, a
traditional Chinese medicine prescription, induces cell-cycle arrest and apoptosis in human liver cancer cells in vitro and in vivo." J
Gastroenterol Hepatol.
Hu, J. P., K. Nishishita, et al. (2008). "Berberine inhibits
RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways." Eur J Pharmacol 580(1-2): 70-9.
Jankun, J., S. H. Selman, et al. (2006). "Nutraceutical inhibitors of urokinase: potential applications in prostate cancer prevention and treatment." Oncol Rep 16(2): 341-6.
Jing, L., L. Liu, et al. (2004). "Expression of myopodin induces suppression of tumor growth and metastasis." Am J Pathol 164(5):
1799-806.
Joukov, V., V. Kumar, et al. (1998). "A recombinant mutant vascular endothelial growth factor-C that has lost vascular endothelial growth factor receptor-2 binding, activation, and vascular permeability
activities." J Biol Chem 273(12): 6599-602.
Jung, J. E., H. S. Kim, et al. (2007). "Caffeic acid and its synthetic derivative CADPE suppress tumor angiogenesis by blocking
STAT3-mediated VEGF expression in human renal carcinoma cells."
Carcinogenesis 28(8): 1780-7.
Kim, S. U., D. Y. Kim, et al. (2008). "Hepatocellular carcinoma presenting with bone metastasis: clinical characteristics and prognostic factors." J Cancer Res Clin Oncol.
Klagsbrun, M. and P. A. D'Amore (1996). "Vascular endothelial growth factor and its receptors." Cytokine Growth Factor Rev 7(3): 259-70.
Kusunose, M., B. Qiu, et al. (2002). "Effect of Sho-saiko-to extract on hepatic inflammation and fibrosis in dimethylnitrosamine induced liver injury rats." Biol Pharm Bull 25(11): 1417-21.
Lau, F. Y., C. H. Chui, et al. (2005). "Antiproliferative and apoptosis-inducing activity of Brucea javanica extract on human carcinoma cells." Int J Mol Med 16(6): 1157-62.
Lee, H. and J. Y. Lin (1988). "Antimutagenic activity of extracts from anticancer drugs in Chinese medicine." Mutat Res 204(2): 229-34.
Li, R., R. R. Walvekar, et al. (2008). "Unresectable hepatocellular carcinoma with a solitary metastasis to the mandible." Am Surg 74(4):
346-9.
Lin, C. S., C. L. Kuo, et al. (2007). "Growth inhibitory and apoptosis inducing effect of Perilla frutescens extract on human hepatoma HepG2 cells." J Ethnopharmacol 112(3): 557-67.
Lin, C. S., C. L. Kuo, et al. (2007). "Growth inhibitory and apoptosis inducing effect of Perilla frutescens extract on human hepatoma HepG2
cells." J Ethnopharmacol 112(3): 557-67.
Lin, S., S. C. Tsai, et al. (2004). "Berberine inhibits HIF-1alpha expression via enhanced proteolysis." Mol Pharmacol 66(3): 612-9.
Lin, Y., L. K. Ong, et al. (1995). "Differential in situ hybridization for determination of mutational specific expression of the p53 gene in human hepatoma cell lines." Pathology 27(2): 191-6.
Liu, F. and T. B. Ng (2000). "Antioxidative and free radical scavenging activities of selected medicinal herbs." Life Sci 66(8): 725-35.
Lu, J. S., Y. Q. Liu, et al. (2007). "[Protective effects and its mechanisms of total alkaloids from rhizoma Coptis chinensis on
Helicobacter pylori LPS induced gastric lesion in rats]." Zhongguo Zhong Yao Za Zhi 32(13): 1333-6.
Ma, Z., K. Otsuyama, et al. (2005). "Baicalein, a component of Scutellaria radix from Huang-Lian-Jie-Du-Tang (HLJDT), leads to suppression of proliferation and induction of apoptosis in human myeloma cells." Blood 105(8): 3312-8.
McGowan, P. M. and M. J. Duffy (2008). "Matrix metalloproteinase expression and outcome in patients with breast cancer: analysis of a published database." Ann Oncol.
Mirzoeva, S., N. D. Kim, et al. (2008). "Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells." Mol Carcinog 47(9): 686-700.
Paku, S. (1998). "Current concepts of tumor-induced angiogenesis."
Pathol Oncol Res 4(1): 62-75.
Pepper, M. S. and M. Skobe (2003). "Lymphatic endothelium:
morphological, molecular and functional properties." J Cell Biol 163(2):
209-13.
Renzulli, C., F. Galvano, et al. (2004). "Effects of rosmarinic acid against aflatoxin B1 and ochratoxin-A-induced cell damage in a human hepatoma cell line (Hep G2)." J Appl Toxicol 24(4): 289-96.
Ryu, S. Y., M. H. Oak, et al. (2000). "Anti-allergic and
anti-inflammatory triterpenes from the herb of Prunella vulgaris." Planta Med 66(4): 358-60.
Shirataki, Y., N. Motohashi, et al. (2001). "In vitro biological activity of prenylflavanones." Anticancer Res 21(1A): 275-80.
Su, B. N., L. C. Chang, et al. (2002). "Bioactive constituents of the seeds of Brucea javanica." Planta Med 68(8): 730-3.
Sun, B., D. Zhang, et al. (2007). "Hypoxia influences vasculogenic mimicry channel formation and tumor invasion-related protein expression in melanoma." Cancer Lett 249(2): 188-97.
Takahashi, K., E. Uejima, et al. (2003). "In vitro inhibitory effects of Kampo medicines on metabolic reactions catalyzed by human liver microsomes." J Clin Pharm Ther 28(4): 319-27.
Tapia, A., L. A. Salamonsen, et al. (2008). "Leukemia inhibitory factor promotes human first trimester extravillous trophoblast adhesion to extracellular matrix and secretion of tissue inhibitor of
metalloproteinases-1 and -2." Hum Reprod 23(8): 1724-32.
Tischer, E., R. Mitchell, et al. (1991). "The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing." J Biol Chem 266(18): 11947-54.
Tu, G., W. Xu, et al. (2008). "Progress in the development of matrix
metalloproteinase inhibitors." Curr Med Chem 15(14): 1388-95.
Wu, X. Z., G. R. Xie, et al. (2007). "Hypoxia and hepatocellular carcinoma: The therapeutic target for hepatocellular carcinoma." J Gastroenterol Hepatol 22(8): 1178-82.
Xiang, D., D. Wang, et al. (2006). "Caffeic acid phenethyl ester induces growth arrest and apoptosis of colon cancer cells via the beta-catenin/T-cell factor signaling." Anticancer Drugs 17(7): 753-62.
Xu, F., Z. G. Ou-Yang, et al. (2006). "Sodium caffeate induces
endothelial cell apoptosis and inhibits VEGF expression in cancer cells."
Yao Xue Xue Bao 41(6): 572-6.
Yoshiji, H., S. Kuriyama, et al. (2003). "Extracellular matrix
remodeling may predominate over hepatocyte injury in hepatocellular carcinoma development." Oncol Rep 10(4): 957-62.
Yu, Z. L., X. R. Liu, et al. (2004). "[Anticancer effects of various fractions extracted from Dioscorea bulbifera on mice bearing HepA]."
Zhongguo Zhong Yao Za Zhi 29(6): 563-7.
Yurchenco, P. D. and J. C. Schittny (1990). "Molecular architecture of basement membranes." Faseb J 4(6): 1577-90.
Zachary, I. (2001). "Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor." Am J Physiol Cell Physiol 280(6): C1375-86.
Zhang, L. Z., Y. J. Guo, et al. (2008). "[A novel triterpenoid saponin from Prunella vulgaris]." Yao Xue Xue Bao 43(2): 169-72.
Zhang, Q., X. Tang, et al. (2006). "Green tea extract and
(-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human
cervical carcinoma and hepatoma cells." Mol Cancer Ther 5(5): 1227-38.
Zhang, S. D., Y. X. Fang, et al. (2007). "[Extraction and anti-tumor activity study of polysaccharide in several traditional Chinese medicine]."
Zhong Yao Cai 30(2): 179-82.
許鴻源（1985）簡明藥材學，新醫藥出版社(台灣)。
謝明村（1996）中藥學概論，中國古典醫籍新解叢書（台北市）
成佳憲，行政院衛生署，中醫藥委員會 95 年度計畫編號：
CCMP95-RD-210 中藥材黃連組成物對肺癌及肝癌放射線治療動物模 式之免疫調控因子基因表現
行政院衛生署，衛生統計資料
（http://www.cichb.gov.tw/sta_information/sta_informations.asp）
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