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Image Registration and Fusion of Brain Magnetic Resonance Imaging and Magnetic Resonance Angiography 劉哲瑋、金憲 ; 傅家啟

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Image Registration and Fusion of Brain Magnetic Resonance Imaging and Magnetic Resonance Angiography

劉哲瑋、金憲 ; 傅家啟

E-mail: 9607384@mail.dyu.edu.tw

ABSTRACT

Along with a number of medical imaging development、through Computed Tomography(CT)to medical imaging to do a special analysis with the appropriate treatment、can be specific organizations or lesions reservations or prominent. But just from a single type of the images do not get enough information、So will many types of medical imaging and calibration together it is of some importance. Fault for 3D medical image reconstruction of the space volume of modern medical technology is a major

advancement、CT images provide information not only be structural images. For example,Magnetic Resonance Imaging(MRI)

、Magnetic Resonance Angiography(MRA). Each CT images provide a variety of medical information. by image calibration (Image Registration) and integration (Image Fusion ) technology to integrate various imaging message、combining the advantages of two types of images、give physicians in the diagnosis or treatment of more information to help diagnosis. In this paper visualization of the location of brain gliosis and intracranial arterial stenosis two different medical imaging、Scatter Search(SS)and the Genetic Algorithm(GA)to search for the best geometric calibration parameters for conversion of 3D image calibration and integration、and the results of 3D visualization、to provide physicians lesions regions 3D information. Due to the experimental results show that SS in calibration error is the smallest GA. In this paper、through image processing and 3D reconstruction imaging technology development and computer-aided diagnosis system、3D visualization of the location of brain gliosis and intracranial arterial stenosis. Discrimination by professionals if they have any relevance to improve clinical diagnosis of medical quality.

Keywords : Gliosis ; Magnetic Resonance Image ; stenosis of vessel ; Three Dimensional Visualization Table of Contents

封面內頁 簽名頁 授權書 中文摘要... iv ABSTRACT... v 誌 謝... vi 目 錄... vii 圖目錄... x 表目

錄... xii 第一章 緒論... 1 1.1 研究背景與動機... 1 1.2 研究範圍與目 的... 2 1.3 研究方法... 2 第二章 文獻探討... 4 2.1 影像校準之相關研 究... 4 2.1.1 有標記式導向... 5 2.1.2 無標記式導向... 5 2.2 影像前處

理... 6 2.2.1 Active Contours using Level Sets介紹[10].. 6 2.2.2 影像強化... 11 2.3 最佳化參 數選擇... 12 2.3.1 分散搜尋法(Scatter search)... 12 2.3.2 基因演算法(Genetic Algorithm)... 18 2.3.3 最佳化參數演算法差異... 21 2.4 績效評估... 23 第三章 研究架構與方法... 25 3.1 研究架構... 25 3.2 影像校準... 25 3.2.1 轉換參數(Transformation Parameters).... 26 3.2.2 校準相似度量測準則(Similarity Metric).. 27 3.2.3 最佳化參數搜尋演算法... 28 3.3 最佳化演算法搜尋校準 幾何轉換參數... 28 3.3.2 SS演算法搜尋校準幾何轉換最佳參數組合... 29 3.3.3 GA演算法找尋校準幾何轉換最佳參數組 合... 30 3.4 模擬影像校準及其績效衡量研究方法... 31 3.4.1 影像前處理... 32 3.4.2 最佳化參數搜 尋... 35 3.4.3 績效衡量... 36 3.5 實際影像校準及融合... 37 3.5.1 影像前處 理... 38 3.5.2 影像校準... 39 3.5.3 影像融合... 40 第四章 實驗設計與分 析... 42 4.1 模擬影像校準實驗結果與分析... 42 4.1.1 模擬影像來源及實驗設置... 44 4.1.2 模擬 影像校準實驗結果與分析... 45 4.1.3 模擬影像校準結果與績效衡量... 57 4.2 實際影像校準實驗結果與分 析... 58 4.2.1 實際影像校準實驗設置... 58 4.2.2 實際影像校準結果... 59 4.2.3 實際影像融 合... 61 第五章 結論與未來展望... 63 5.1 結論... 63 5.2 未來展

望... 63 參考文獻... 65 REFERENCES

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