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I J K L M N O P 9 Q * R Texas Instruments [Ref 1]

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         ! "# $ %  & '   ( ) * ( + , - ./ 0 1 2 3 4 5 -4 6 7 8 9 .  & ' : ; .< =

> 8 9 ? & '   @ A  B C D D E    F G H

 I J K L M N O  P 9 Q * R Texas Instruments [Ref 1]

S T U V P 9 surface plasmon resonance ( SPR ) 5 W  

F G H  X Kretschmann Y Z [\ ] ^ _` a b 

c de f g h (i U j e h ) k l m n o l ` a p q e f h l m r s t u v w r (called Brewsrer’s angle) x  y z m "{

| } ~  & € ;  X plasma ‚ ƒ _e f „  , - …

† ‡ ˆ ‰ Š ‹  l m | Œ  Ž   q e f g h e f 5 ' x

  ‘ 8 9 ’ “ _v w r ” z m n • s x  – — ˜™ "

r s š › [ ‘ r Ek e f g h _œ  ž Ÿ  ¡ ” (¢ m £ ]

˜ )  ‘ r ¤ ¥ ¦ § ¨  ‘ r ¥ ¦ ; © ª « ¬ ­  ] ˜

® ¯ * ° 1.1E

1.1 SPR        ([Ref 2]

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2

± ² J ³ ´    µ ¶   · W ¸ P 9 u n ¹   F G

dS T n ¹ P 9 º W ¸ » F G € A J ¼ t u ½ ¾ ™ ¿

ÀE

n ¹ P 9 d Á  9 i ( 1 2 En ¹ Ã Ä j , Å n Æ ž

Ÿn ¹ Ç È É Ê Ë .Ì Í Î .œ Ï | } Ð Ñ D Ò Ó Ô X

_X Õ n ¹ ^ Ö , Å n Æ × > Ø Ù Ù  Ú ; Û .6 Ü

Ý    Þ   n ¹ F G H   ß o Q * à ; F G H .

á â ã a .ä A F G H . @ F G H D å æ  ¬ 

n ' ç 6 n ¹ è 9 é m Ì € , Å Eê æ S T œ ¸ | ë .ë ì . í ™ î å æ ï  .ð ñ  è ò u n ¹ F G H P 9 E

‹  ó ô    %    µ ¶ õ ó ô e f g h ›

[ propagating surface plasmon resonance (PSPR)9 ö &

localized surface plasmon resonance (LSPR) œ  ES T PSPR÷

LSPR_biosensord ¼ ø   Ú _ù ú s d û ü Ø  f

ö ý þ   Ü ; G ( _cm

2

~ mm

2

D  )õ     d

(m

2

X ” )  G u ELSPR P 9 %  ² Ø œ

# $    H 1 2 "    dP 9 e    ó ô 

' 8 [n ¹ d F G   ¬ Ý ö ý è    B G

biosensorE

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3

 9 PSPR  LSPR 5 W  “   F G H (biosensor) 

j  9 ž Ÿ ž | U  ] ˜8 [ G § ¨ J j S T  

 G  ƒ [è X t u . ! " :   & ' (lable free).

# { (real time).ù ú s Ì (high sensitivity).@ $ & % (kinetic study).: > : ; & ' & ' 8 9 (characterize and quantify).X ? ( ) ƒ ; * +  G (high throughput screening)D Ò Ó "³ ,

  - A J "õ .      ³ ,  / 0 E

à 1 2 3 = 4 n ¹ P 9 Ö 5 q 6 7 8 9 × >  ó ô 

n ¹ F G H E:

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