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[PDF] Top 20 Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways.

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Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways.

Cantharidin induces apoptosis of H460 human lung cancer cells through mitochondria-dependent pathways.

... in H460 cells In order to delineate the mechanism of cell apopotosis mediated by cantharidin, we performed DNA fragmentation assay, since DNA fragmentation is the characteristic for ... See full document

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Cantharidin Induces DNA Damage and Inhibits DNA Repair-Associated Protein Levels in NCI-H460 Human Lung Cancer Cells

Cantharidin Induces DNA Damage and Inhibits DNA Repair-Associated Protein Levels in NCI-H460 Human Lung Cancer Cells

... 2010. Cantharidin induces apoptosis in human bladder cancer TSGH 8301 cells through mitochondria-dependent signal ...2010. Cantharidin, a potent and ... See full document

17

Cantharidin induces G2/M phase arrest via the inhibitions of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria-dependent pathways of A375.S2 human melanoma cells

Cantharidin induces G2/M phase arrest via the inhibitions of Cdc25c and Cyclin A and triggers apoptosis through reactive oxygen species and the mitochondria-dependent pathways of A375.S2 human melanoma cells

... body of mylabris (Mylabris phalerata Pallas) has been used in Chinese traditional medicine for the treatment of cancer since long ago .... Cantharidin (CTD), a terpenoid, was isolated from ... See full document

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Cantharidin induces apoptosis in human bladder cancer TSGH8301 cells through mitochondria-dependent signal pathways

Cantharidin induces apoptosis in human bladder cancer TSGH8301 cells through mitochondria-dependent signal pathways

... Apparently, cantharidin-induced cytotoxicity may have cell type ...whether cantharidin- induced cytotoxicity was related to MAPK pathways in bladder cancer TSGG 8301 ...8301 cells when ... See full document

8

Demethoxycurcumin induces the apoptosis of human lung cancer NCI-H460 cells through the mitochondrial-dependent pathway

Demethoxycurcumin induces the apoptosis of human lung cancer NCI-H460 cells through the mitochondrial-dependent pathway

... and apoptosis associated protein expression in NCI H460 ...cells. Cells were exposed to either vehicle or DMC (35 uM) for various time ...periods. Cells were harvested and total ... See full document

16

Capsaicin Induces Apoptosis in SCC-4 Human Tongue Cancer Cells Through Mitochondria- Dependent and -Independent Pathways

Capsaicin Induces Apoptosis in SCC-4 Human Tongue Cancer Cells Through Mitochondria- Dependent and -Independent Pathways

... ingredient of red pepper, genus Capsicum, and has been shown to induce apoptosis of many tumors cells (Hail, 2003; Ito et ...capsaicin-induced apoptosis (Lee et ...and apoptosis ... See full document

13

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

... HL-60 CELLS; OXIDATIVE STRESS; DEATH; MECHANISMS; ARREST; ANTHRAQUINONES; INVOLVEMENT; ACTIVATION; INDUCTION; ROOTS Abstract: Emodin was isolated from Rheum palmatum ...on human cancer cell lines, ... See full document

3

Emodin Induces Apoptosis of Human Tongue Squqmous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Emodin Induces Apoptosis of Human Tongue Squqmous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

... on human cancer cell lines, however, the molecular mechanisms of emodin-mediated apoptosis in human tongue cancer cells have not been fully ...treatment of ... See full document

1

Capsaicin induces apoptosis in SCC-4 human tongue cancer cells through mitochondria-dependent and -independent pathways.

Capsaicin induces apoptosis in SCC-4 human tongue cancer cells through mitochondria-dependent and -independent pathways.

... fields of surgery, radiotherapy, and chemotherapy of tongue cancer, the cure rates are still not substantially ...ingredient of hot chili pepper and has been reported to have an antitumor ... See full document

10

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways.

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways.

... on human cancer cell lines, however, the molecular mechanisms of emodin-mediated apoptosis in human tongue cancer cells have not been fully ...treatment of ... See full document

9

Bisdemethoxycurcumin-induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathways in human lung cancer NCI H460 cells.

Bisdemethoxycurcumin-induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathways in human lung cancer NCI H460 cells.

... activities of caspase-3, -8 and -9 in NCI H460 ...cell apoptosis through caspase-dependent, NCI H460 cells were incubated with BDMC for various time periods ... See full document

25

Ellagic acid induces apoptosis in tsgh8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways

Ellagic acid induces apoptosis in tsgh8301 human bladder cancer cells through the endoplasmic reticulum stress- and mitochondria-dependent signaling pathways

... interaction of cell proliferation and cell death, if cell growth is inhibited, then it will lead to the decrease of cell proliferation and the increase of cell ...One of the major regulatory ... See full document

13

Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways

Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways

... DAS-treated cells (Table I). The top scorers by the number of pathways network from GeneGo analysis program is shown in ...fragments of canonical ...and apoptosis, inducing the effect ... See full document

9

Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways

Cantharidin induces G2/M phase arrest and apoptosis in human colorectal cancer colo 205 cells through inhibition of CDK1 activity and caspase-dependent signaling pathways

... activation of effector caspases such as caspase-3 and -7 by initiator caspases (caspase-8 and caspase-9) are responsible for the cleavage of cellular substrates then degrades the chromosomes into ... See full document

28

PEITC Induces Apoptosis in Human Malignant Melanoma A375.S2 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

PEITC Induces Apoptosis in Human Malignant Melanoma A375.S2 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

... The results showed that PEITC caused chromatin condensation, DNA damage, cell cycle G2/M phase arrest, promoted ROS generation, stimulated Ca2+ release, loss of ΔΨm and activated caspa[r] ... See full document

1

Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway

Triptolide induces apoptosis in human adrenal cancer NCI-H295 cells through a mitochondrial-dependent pathway

... promote apoptosis in a variety of cell types (28-33) including normal human proximal tubular epithelial HK-2 cells in vitro ...induced apoptosis in human adrenal cancer ... See full document

7

Glycyrrhizic acid induces apoptosis in WEHI-3 mouse leukemia cells through the caspase- and mitochondria-dependent pathways

Glycyrrhizic acid induces apoptosis in WEHI-3 mouse leukemia cells through the caspase- and mitochondria-dependent pathways

... induced apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathway in human osteosarcoma U-2 OS ...polymerization, induces mitotic arrest, and triggers ... See full document

7

cDNA microarray analysis of the effect of cantharidin on DNA damage, cell cycle and apoptosis-associated gene expression in NCI-H460 human lung cancer cells in vitro

cDNA microarray analysis of the effect of cantharidin on DNA damage, cell cycle and apoptosis-associated gene expression in NCI-H460 human lung cancer cells in vitro

... be dependent on oncogenes for tumor initiation and progression; this concept has therefore been named oncogene addiction ...signaling pathways have also been examined, such as the molecular chaperone ... See full document

10

Cantharidin induces apoptosis through the calcium/PKC-regulated endoplasmic reticulum stress pathway in human bladder cancer cells

Cantharidin induces apoptosis through the calcium/PKC-regulated endoplasmic reticulum stress pathway in human bladder cancer cells

... regulator of cellular growth. It has been suggested that dysregulation of calcium homeostasis drives the expression of malignant phenotypes, including proliferation, migration, invasion and ... See full document

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Rhein Induced Apoptosis through the Endoplasmic Reticulum Stress, Caspase- and Mitochondria-dependent Pathways in SCC-4 Human Tongue Squamous Cancer Cells

Rhein Induced Apoptosis through the Endoplasmic Reticulum Stress, Caspase- and Mitochondria-dependent Pathways in SCC-4 Human Tongue Squamous Cancer Cells

... Rhein; apoptosis; caspase; mitochondria; DNA damage; SCC-4 human tongue cancer cells KeyWords Plus: ACTIVATION; PROTEOLYSIS; PROTEASES Abstract: Rhein, an anthraquinone compound, can be ... See full document

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