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[PDF] Top 20 The fate of regulatory T cells: survival or apoptosis

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The fate of regulatory T cells: survival or apoptosis

The fate of regulatory T cells: survival or apoptosis

... + regulatory T (Treg) cells are unique in their immunosuppressive abilities and contribute to immune ...However, the homeostatic processes and survival programs that maintain the ... See full document

12

ALTERNATIVE SPLICING OF THE FOXP3 GENE IN REGULATORY T CELLS IS A PROGNOSTIC FACTOR FOR ADJACENT DC THERAPY IN GLIOBLASTOMA MULTIFORME

ALTERNATIVE SPLICING OF THE FOXP3 GENE IN REGULATORY T CELLS IS A PROGNOSTIC FACTOR FOR ADJACENT DC THERAPY IN GLIOBLASTOMA MULTIFORME

... Institute of Immunology, China Medical University, Taichung, ...As the most malignant high-grade glioma, prognosis for patients with glioblastoma multiforme (GBM) has only a median survival of ... See full document

2

CCT327 enhances TRAIL-induced apoptosis through the induction of death receptors and downregulation of cell survival proteins in TRAIL-resistant human leukemia cells

CCT327 enhances TRAIL-induced apoptosis through the induction of death receptors and downregulation of cell survival proteins in TRAIL-resistant human leukemia cells

... HL60-TR cells to TRAIL-sensitive cells. Activation of caspases is an important hallmark of apoptosis induced by most ...whether the effect of CCT327 on TRAIL-induced cell ... See full document

33

CD4+ T cells disarm or delete cytotoxic T lymphocytes under IL-17-polarizing conditions

CD4+ T cells disarm or delete cytotoxic T lymphocytes under IL-17-polarizing conditions

... frequency of IL-17–secreting CD4 + T cells (termed Th17) and an elevated CD8 + IL-17 + T cell population (termed ...+ cells fail to behave like most cytotoxic T lymphocytes that ... See full document

10

An Increase in CD3+CD4+CD25+ Regulatory T Cells after Administration of Umbilical Cord-Derived Mesenchymal Stem Cells during Sepsis

An Increase in CD3+CD4+CD25+ Regulatory T Cells after Administration of Umbilical Cord-Derived Mesenchymal Stem Cells during Sepsis

... assess the effects of MSC administration after CLP-induced polymicrobial sepsis, rats of BMMSC and UCMSC groups received five millions BMMSCs and UCMSCs in ...via the tail vein 4 hours after ... See full document

3

The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells

The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells

... regions of the HER-2 tyrosine kinase ...effects of these agents in the HER-2-overexpressing BT474 breast cancer cell ...inhibited the survival of BT474 cells, in ... See full document

1

Compensatory effect of IGF-I survival signaling is reduced by aging to accelerate apoptosis in cardiac cells exposed to second-hand smoke

Compensatory effect of IGF-I survival signaling is reduced by aging to accelerate apoptosis in cardiac cells exposed to second-hand smoke

... risk of coronary artery ...impairment of normal heart functios, due to an increasing vulnerability, which reduces the ability of ...survive. The aim of this study was to examine ... See full document

1

Antibiotics induce apoptosis of human peritoneal mesothelial cells

Antibiotics induce apoptosis of human peritoneal mesothelial cells

... cell apoptosis NEPHROLOGY 143 Although the PMC is crucial for CAPD, CAPD itself has detrimental effects on ...One of the most important changes is peritoneal fibrosis. The pathogenesis ... See full document

8

Norcantharidin modulates development of dendritic cells and prolongs skin allograft survival

Norcantharidin modulates development of dendritic cells and prolongs skin allograft survival

... expanding T-regulatory cells either through drug therapy or ex vivo cell therapy is being considered as novel transplant tolerance-induction strategies ...evaluated the effect of ... See full document

54

TLR2 Agonists Enhance CD8+Foxp3+ Regulatory T Cells and Suppress Th2 Immune Responses during Allergen Immunotherapy

TLR2 Agonists Enhance CD8+Foxp3+ Regulatory T Cells and Suppress Th2 Immune Responses during Allergen Immunotherapy

... expanded the CD8 + CD25 + Foxp3 + Treg population and inhibited ...Treg cells directly suppressed CD4 + T cell proliferation by cell-contact ...Treg cells, but not CD4 + CD25 + Treg ... See full document

14

Apoptosis-dependent and-independent mechanisms mediate the phagocytic recognition/clearance of theHL60-A1 transfectants of prolonged survival.

Apoptosis-dependent and-independent mechanisms mediate the phagocytic recognition/clearance of theHL60-A1 transfectants of prolonged survival.

... 摘要:OBJECTIVE: The phagocytic recognition and clearance of the recruited inflammatory cells with prolonged survival play a pivotal role in relieving tissue inflammation and maintaining ... See full document

2

Induction of Apoptosis in Human Hep G2 Cells

Induction of Apoptosis in Human Hep G2 Cells

... words: apoptosis; glucose transporters; Hep G2 cells; phloretin; paclitaxel INTRODUCTION Glucose transport across the plasma membrane is the rate-limiting step in its subsequent utilization, ... See full document

12

Regulatory Mechanism of 17β-estradiol and/or Estrogen Receptor β on Hypoxia-induced BNIP3 Autophagic and Apoptotic Pathways in H9c2 Cardiomyoblast Cells

Regulatory Mechanism of 17β-estradiol and/or Estrogen Receptor β on Hypoxia-induced BNIP3 Autophagic and Apoptotic Pathways in H9c2 Cardiomyoblast Cells

... overexpression cells. E2/ER β overexpression even further promoted the cardiac survival pathway related proteins, p-IGF1R and p-Akt ...exerts the protective effect through repressed ... See full document

1

Helicobacter pylori-derived heat shock protein 60 increases the induction of regulatory T cells

Helicobacter pylori-derived heat shock protein 60 increases the induction of regulatory T cells

... presentation of self Ags or other, as yet elusive, mechanisms. The 5-aa shared epitope (SE) motif in HLA- DRB1 increases both the risk of rheumatoid arthritis development and the ... See full document

3

Upregulation of autophagy by inhibitors of mTOR or caspases decreases splenic T cell apoptosis in sepsis

Upregulation of autophagy by inhibitors of mTOR or caspases decreases splenic T cell apoptosis in sepsis

... Upregulation of autophagy by inhibitors of MTOR or caspases decreases splenic T cell apoptosis in sepsis Ya-Ching Hsieh 1 , Hsiang-Wei Hsueh 1 , Chi-Hsun Hsieh 2 , Shyng-Shiou Yuan 1,3 ... See full document

1

Differential induction of apoptosis in oncogene-transformed NIH 3T3 cells by methylmethanesulfonate

Differential induction of apoptosis in oncogene-transformed NIH 3T3 cells by methylmethanesulfonate

... Finally, Bcl-2 protein was found to be elevated in v-H-ras transformed cells but not in normal or other oncogene-transformed cells, suggesting that Bcl-2 may play a role[r] ... See full document

8

A bovine whey protein extract can induce the generation of regulatory T cells and shows potential to alleviate asthma symptoms in a murine asthma model

A bovine whey protein extract can induce the generation of regulatory T cells and shows potential to alleviate asthma symptoms in a murine asthma model

... Regulatory T cells from atopic individuals are defective in suppressing T H 2 cell function compared with those from non-atopic ...depleting regulatory T cells or ... See full document

1

The function of regulatory T cell on macrophage activities is dysregulated following trauma-hemorrha

The function of regulatory T cell on macrophage activities is dysregulated following trauma-hemorrha

... University of Alabama at Birmingham, USA. Regulatory T cells (Tregs) are potent immune ...to the T cell suppression following trauma- hemorrhage ...sham, T-H (laparotomy, ... See full document

1

Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species

Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species

... Keywords: Apoptosis, Gastric cancer, Necrosis, Shikonin a b s t r a c t The effects of shikonin on gastric cancer cells were investigated in this ...reduced the viability ... See full document

5

Expression of CD25high Regulatory T Cells and PD-1 in Gastric Infiltrating CD4+ T Lymphocytes in Patients with Helicobacter pylori Infection

Expression of CD25high Regulatory T Cells and PD-1 in Gastric Infiltrating CD4+ T Lymphocytes in Patients with Helicobacter pylori Infection

... epithelial cells after H. pylori exposure promotes development of CD4 ⫹ CD25 ⫹ FoxP3 ⫹ regulatory T cells ...⫹ T cells were shown to accumulate in the human ... See full document

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