[PDF] Top 20 Polymorphisms in Cell Cycle Regulatory Genes; Urinary Arsenic Profile and Urothelial Carcinoma

... genotype and UC risk, neither in a dominant, nor in a recessive ...of urinary arsenic species, cumulative exposure of cigarette smoking and 8-OHdG levels is similar among three ... See full document

... 5+ and DMA 5+ . The relative proportion of each arsenic species (InAs%, MMA% and DMA%) was calculated by dividing the concentration of each species by the total arsenic ...age, urinary ... See full document

... ntroduction: Polymorphisms in p53, p21 and CCND1 could regulate the progression of the cell cycle and might increase the susceptibility to inorganic arsenic-related cancer ... See full document

... Materials and methods Study participants A hospital-based case–controlled study was ...cases and 300 healthy participants as controls from the Medical Center that includes National Taiwan University ... See full document

... decreased in people who carried heterozygous genotype of GSTO2 142 ...lower urinary MMA% in people who carried the homogenous variant genotype of GSTO2 142 Asp/Asp compared to those who carried the ... See full document

... Martial and Methods Total 159 and 308 matched cases and controls were respectively recruited at the Department of Urology and Family Medicine, China Medical University Hospital in ... See full document

... dyes and pesticides, chronic medication history, con- sumption of conventional and alternative medicines, and person- al and family histories of urological ...sample and data ...urine ... See full document

... dyes and pesticides, chronic medication history, con- sumption of conventional and alternative medicines, and person- al and family histories of urological ...sample and data ...urine ... See full document

... of urothelial carcinoma (UC) at a 12-year follow-up, and significant associations of cumulative arsenic exposure (CAE) and MMA% (or and DMA%) on UC risk were also found ...that ... See full document

... GAS5 in female patients with bladder urothelial carcinoma (BLCA) with larger tumor size was much lower than that in patients with a smaller tumor size (p = ...analysis and the log–rank ... See full document

... Abstract Arsenic exposure is associated with an increased risk of urothelial carcinoma ...risk and urinary arsenic profile in subjects without evident exposure, 177 ... See full document

... demographic and socioeconomic characteristics, general potential risk factors for malignancies such as lifestyle, alcohol consumption, cigarette smoking in quantified details, exposure to potential ... See full document

... demographic and socioeconomic characteristics, general potential risk factors for malignancies such as lifestyle, alcohol consumption, cigarette smoking in quantified details, exposure to potential ... See full document

... results. In the current study, selection bias was minimized even through cases and controls recruited from two different hospitals, because these hospitals both belonged to medical centers and ... See full document

... interview and participant specimen ...demographic and socioeconomic characteristics; general potential risk factors for malignancies such as lifestyle, cigarette smoking, alcohol, tea, and coffee ... See full document

... of urinary arsenic species and NNK-related metabolites, including total NNAL and the ratio of NNAL-Gluc/free NNAL, on ...UC. In a recent study, we did not find a significant interaction ... See full document

... This study showed that the mean urinary concentration of total arsenics was significantly higher, at 37.67+/-2.98 microg/g creatinine, for UC patients than for healthy controls of 21.1[r] ... See full document

... Abstract: Arsenic is a human carcinogen, and previous studies have demonstrated that it may act through the inhibition of DNA repair mechanisms and the disruption of mitosis to induce apoptosis ... See full document

... interview and specimens collection Well-trained personnel carried out standardized personal interviews based on a structured ...demographic and socioeconomic characteristics, general potential risk factors ... See full document

... interview and specimens collection Well-trained personnel carried out standardized personal interviews based on a structured ...demographic and socioeconomic characteristics, general potential risk factors ... See full document