未來研究方向與建議

期望能撰寫一資訊輸入介面連結類神經網路預測模型，提供臨床醫護人員一簡單便利 的變數輸入介面，進而提高類神經網路預測模型的使用頻率，並在日後收集更多的含 碘顯影劑不良反應風險問卷資料，以期能使預測模型更穩定且可以達到提升預測模型 的準確率，使整個類神經網路預測模型更具臨床輔助上的實用價值。

參考資料

中文文獻

王朝曦。(民 93 年)。利用類神經模型來估計電源線的電流波形之研究。國立中央大學 電機工程研究所碩士論文，未出版，中壢市。

王嬿甄。(民 96 年)。利用小鼠皮膚過敏模式評估六種農藥佐劑之安全性。朝陽科技大 學生物技術研究所碩士論文，台中市。

王鐘賢。(2008)。實用解剖與生理學。台中市：華格那企業。

吳明隆。(2009)。SPSS 操作與應用問卷統計分析實務 (第二版)。台北市：五南。

李潤川、鄧木火、王世叡。(1997)。含碘對比劑事前試驗的預測價值。中華放射醫誌，

22，189-192。

周華、連恆榮、陳燕惠。(2004)。ADR 通報之藥品分析-含碘顯影劑。藥物安全簡訊，

6，7-10。

周鵬程。(2001)。遺傳演算法原理與應用-活用 Matlab。台北市：全華科技。

張斐章、張麗秋。(2006)。類神經網路 (初版)。台北市：東華書局。

莊克士。(1998)。醫學影像物理學。台北市：合記。

陳榮邦、李三剛、黃國茂、周宜宏。(2009)。推動全國放射線檢查之病人安全流程與 作業概況。中華民國放射線醫學會會訊，12，4-8。

黃百寬、蔡金築、夏清智、徐永勳。(2008)。顯影劑腎病變－個案報告和文獻回顧。

內科學誌，2(20)，171-180。

葉怡成。(2009)。類神經網路模式應用與實作 (九版)。台北市：儒林圖書。

謝明芝、陳啟昌、李潤川、陳榮邦。(2008)。放射線檢查之用藥安全流程。中華放射 醫誌，33，85-90。

蘇木春、張孝德。(2000)。機器學習：類神經網路、模糊系統以及基因演算法則。台 北市：全華科技。

英文文獻

Almén T. (1994). The etiology of contrast medium reactions. Investigative Radiology, 29(1), 37-45.

American College of Radiology Manual on Contrast Media. (1998). (4th ed.). Reston, VA:

American College of Radiology.

Amin M.M., Cohan R.H. & Dunnick N.R. (1993). Ionic and nonionic contrast media:

current status and controversies. Appl Radiology, 22, 41-54.

Ansell G., Tweedie M.C., West C.R., Evans P. & Coudh L. (1980). The current status of reactions to intravenous contrast media. Investigative Radiology, 15(6), 32-9.

Baxt W.G. (1995). Application of artificial neural networks to clinical medicine. Lancet, 346(8983), 1135-1138.

Bernstein J.A. (1995). Allergic drug reactions: How to minimize the risks. Postgard Med., 98(2), 159-166.

Boguniewicz M. (1995). Adverse reactions to antibiotics: 1s the patient really allergic?

Drug Safety, 13, 273-280.

Bush W.H., McClennan B.L. & Swanson D.P. (1993). Contrast media reactions: prediction, prevention and treatment. Postgraduate Radiology, 13, 137-147.

Christiansen C. (2005). X-ray contrast media-an overview. Toxicology, 209, 185-187.

Cochran S.T. (2005). Anaphylactoid reactions to radiocontrast media. Curr Allergy Asthma Rep., 5, 28-31.

Cochran S.T., Bomyea K. & Sayre J.W. (2001). Trends in adverse events after IV administration of contrast media. AJR, 176, 1385-1388.

Davies D.M., Ferner R.E. & Glanville H. de. (1998). Davies's Textbook of Adverse Drug

Reactions (5th ed. Vol. 971): Chapman and Hall Medical.

Delaney A., Carter A. & Fisher M. (2006). The prevention of anaphylactoid reactions to iodinated radiological contrast media: a systematic review. BMC Med. Imaging, 6,

（2）.

Descotes J. & Choquet-Kastylevsky G. (2001). Gell and Coombs’s classification : is it still valid ? Toxicology 158, 43-49.

Fogel D.B., Wasson E.C. 3^rd & Boughton E.M. (1995). Evolving neural networks for detecting breast cancer. Cancer Lett, 96(1), 49-53.

Gibby W.A. (2005). Basic principles of magnetic resonance imaging. Neurosurg Clin N Am, 16, 1-64.

Hanley J.A. & McNeil B.J. (1982). The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology, 143(1), 29-36.

Hartman G.W., Hattery R.R., Witten D.M. & Williamson B. Jr. (1982). Mortality during excretory urography: Mayo Clinics experience. AJR, 139, 919-922.

Jagdish Singh & Aditya Daftary. (2008). Iodinated Contrast Media and Their Adverse Reactions. Journal of Nuclear Medicine Technology, 36(2), 69-74.

Jacobson H.G., Lentino W., Poppel M.H. & Zeitel B.E. (1956). Renografin: a new intravenous urographic mediurn. J Urol, 76(4), 461-465.

Katayama H., Yamaguchi K., Kozuka T., Takashima T., Seez P. & Matsuura K. (1990).

Adverse reactions to ionic and nonionic contrast medium. A report from the Japanese committee on the safety of contrast medium. Radiology, 175, 621-628.

Katzberg R. (1992). The Biologic Basis for Disease in Adults and Children. St. Louis, MO:

Mosby.

Laroche D., Namour F., Lefrançois C., Aimone-Gastin I., Romano A., Sainte-Laudy J., Laxenaire M.C. & Guéant J.L. (1999). Anaphylactoid and anaphylactic reactions to iodinated contrast material. Allergy, 54(58), 13–16.

Lawshe C.H. (1975). A quantitative approach to content validity. Personnel Psychology, 28(4), 564-575.

Li A., Wong C.S., Wong M.K., Lee C.M. & Au Yeung M.C. (2006). Acute adverse reactions to magnetic resonance contrast media-gadolinium chelates. The British Journal of Radiology, 79, 368-371.

Meth M.J. & Maibach H.I. (2006). Current understanding of contrast media reactions and implications for clinical management. Drug Safety, 29, 133-141.

Namasivayam S., Kalra M.K., Torres W.E. & Small W.C. (2006). Adverse reactions to intravenous iodinated contrast media: an update. Curr Probl Diagn Radiol. 35, 164-169.

Palmer F.J. (1988). The RACR survey of intravenous contrast media reations: final report.

Australas Radiology, 32, 426-428.

Pendergrass H.P., Tondreau R.L, Pendergrass E.P., Ritchie D.J., Hildreth E.A. & Askovitz S.I. (1958). Reactions associated with intravenous urography: historical and statistical review. Radiology, 71, 1-12.

Schmitt N. & Noe R.A. (1983). Demonstration of content validity: An assessment center example. Journal of Assessment Center Technology, 6, 5-11.

Shehadi W.H. (1982). Contrast media adverse reactions: occurrence, recurrence, and distribution pattern. Radiology, 143(1), 11-17.

Thomsen H.S. & Bush W. (1998). Adverse effects of contrast media: incidence, prevention and management. Drug Safety, 19, 313-324.

Tomida S., Hanai T., Koma N., Suzuki Y., Kobayashi T. & Honda H.( 2002). Artificial Neural Network Predictive Model for Allergic Disease Using Single Nucleotide polymorphisms data. Journal of Biosci Bioeng, 93(5), 470-478.

Venkatesan P. & Anitha S. (2006). Application of a radial basis function neural network for diagnosis of diabetes mellitus. Current Science, 91(9), 10.

Weiss G. (2004). Mining with rarity: a unifying framework. SIGKDD Exploration, 6(1),7-19.

Weng C.G. & Poon J. (2006). A data complexity analysis on imbalanced datasets and an alternative imbalance recovering strategy. International Conference on

IEEE/WIC/ACM, 270-276.

Wortzel R. (1979). Multivariate analysis. New Jersey: Prentice Hall.

電子資料

全球華人健康網（2006 年）．釓 gadolinium．2010 年 11 月 10 日取 自

http://www.jjkkusa.com/modules/news/article.php?storyid=495

佛教慈濟醫院衛教天地（2005 年）．認識含碘顯影劑．2010 年 11 月 09 日取 自

http://www.tzuchi.com.tw/a_f/f_tc/newRED/knowleage/page6_1.htm

國科會高瞻計劃資源平台（2010 年 11 月 01 日）．免疫的副作用－過敏反應（Allergy

reactions）

自

http://highscope.ch.ntu.edu.tw/wordpress/?p=14103

國科會高瞻計劃資源平台（2008 年 12 月 11 日）．硫酸鋇(Barium sulfate)．

癌症專家（2005 年 06 月 01 日）．核磁共振造影．2010 年 11 月 10 日取 自 http://cancer.idv.tw/06-breast/diagnosis.htm

附錄一，含碘顯影劑不良反應風險量表