圖四十八 Coumarin 對 HeLa 細胞株誘發細胞凋亡(apoptosis)與造成細胞週期停 止(cell cycle arrest)的路徑
Coumarin Cell surface
ROS
DNA damage
Apoptosis
DNA fragmentation
MMP ↓
Ca+2 ↑ Cell cycle G0/G1 arrest
p53 ↑ p21 ↑
CDC 25A↓
Bcl-2↓
Bcl-xl↓
Bax↑
cytochrome c ↑ Caspase-9 ↑ Caspase-3 ↑
NF-κB↓
cyclin E CDK 2 ↓
cyclin D↓
CDK4
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自述
自我介紹：學生黃永豊，出生於台中，民國六十四年十二月十六日生，家住 台中市，畢業於東海大學畜產系。學生外表斯文，言談間充滿著親和力，平常樂 於助人，亦喜歡幫助朋友；本人平日亦喜歡運動，故身體狀況不錯，加上平日正 常的飲食和生活習慣，因此身體非常健康。本人做事積極進取，凡事樂觀以對，
做任何事情都很有信心，而一旦做了，就一定要做到最好，這樣一來，才能走向 成功的坦途。
家庭狀況：家父從事旅館業，在南投縣信義鄉東埔溫泉開了一家名為「櫻之 泉」的旅館，家母負責家管，而兩個弟弟分別在雲林和南投念書。
求學過程：學生從小對於學習新鮮的事物皆有濃厚的興趣，小學就讀於中市 忠孝國小，期間表現良好，每學期皆拿到獎狀。國中畢業於中市崇倫國中，在功 課方面表現不錯。五專就讀於中台醫護技術學院，就讀科系為醫事技術科，之後 於民國八十五年畢業後入伍服役，退伍後考上東海大學畜產系，在校期間十分活 躍，系上的迎新露營和牧場迎新，皆邀請學生參與演出，在演唱和演奏上，皆有 亮麗表現，參加農院盃歌唱比賽和全校民歌比賽，皆為比賽的常勝軍。而在學業 方面，亦是收穫頗多，成績皆維持在一定的水準。畢業後考上東吳大學的微生物 所，而由於家母身體欠佳，需要妥善照顧，故最後仍回來台中念書，就讀於中國 醫藥大學。
專長和興趣：學生的專長為醫事檢驗技術，在中台醫護技術學院讀了五年，
亦學到很多醫學類的知識。平日喜歡的興趣包括寫歌、唱歌、畫畫、打籃球…等 等，平日很喜歡運動，因為運動可以防止一些疾病的發生，且有益健康，此外，
對於戲劇方面亦滿有興趣的，以前在校外曾參加過頑石劇團的演出。
未來展望：在畢業之後，其實是另一個全新的開始，亦有一個更大的挑戰在 等著我，而我必須做好準備，去面對一個新的挑戰，在未來，吾希望能精益求精，
凡事必定盡自己最大的努力，全力以赴做到最好，如此才不負家人的期望，並開 拓自己的視野，進而邁向更美好的明天。