6-1 其他氣體之偵測應用
6-1-1 GC/微哨感測器應用於即時偵測金屬錯合物氧氣催化 反應
GC/微哨感測器還可應用於化學反應之動力學測定。圖 4-16 為曾經協助其他實驗室測定化學反應速率所研究的一 種新合成之以錳為中心的金屬配位化合物。將其化合物與雙 氧水反應可的到氧氣產物。圖 4-17 為初步測試兩種反應物不 同體積比的氧氣產率隨時間變化。利用 GC/微哨感測器可以 協助確定雙氧水在哪個濃度下與固定量的化合物反應可以 有最大氧氣產率。
圖 4-17 cat-1[Mn(bdtbpza)2(H2O)2(EtOH)]
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0 200 400 600 800 1000 1200
Volume(µl)
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6-1-2 測定人體呼氣中氧氣/二氧化碳比與血糖的關係
血糖測試目前依然主流測定方法為侵入式的採血檢測。因此本實 驗欲借助 GC/微哨感測器探來討呼氣中氧氣/二氧化碳比值與血糖是 否具依存性。
圖 4-18 為本實驗裝置示意圖。透過人體呼氣之採集，主要以閉 氣後並扣除呼氣管殘留氣體之氣體已採樣袋收集。並且與市售血糖值 測定值相比較。實驗方式為前晚禁食八小時隔日早上進行第一次血糖 值測定，之後每隔一小時進行血糖測定。除了中午攝取正餐之外其餘 時間均無進食。圖 4-19 為人體呼氣層析圖。呼氣的分析結果可在三 分鐘之內完成。由圖 4-20 與圖 4-21 為同一受試者在不同天之 9 小時 之監測結果。數據顯示氧氣/二氧化碳比值與血糖值似乎具有相關性，
然而由於只有一位受試者樣本，因此需要更多固體樣本進行確認。本 實驗目前依然在持續推進當中。可望未來能夠作為另一種替代性的非 侵入式即時血糖偵測方法。
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圖 4-19 實驗裝置示意圖
圖 4-20 人體呼氣層析圖
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圖 4-21 受試者 A 連續九小時監測
圖 4-22 受試者 A 連續九小時監測
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學會發表
(1)參與會議:第一屆美國化學會台灣分會研究生研討會 時間:中華民國 105 年 5 月 29 日
主辦單位 : 美國化學會台灣分會
承辦單位 : 國立臺灣師範大學化學系、國立臺灣大學化學系 題目:
Development and Application of a Milli-Whistle for Use in
Fermentation Process Based on Gas Chromatography Detection
(2)參與會議:第二十三屆分析技術研討會 時間:中華民國 106 年 5 月 27 日
主辦單位 : 科技部自然司化學研究推動中心分析化學組 承辦單位 : 國立中山大學化學系
題目: The use of a gas chromatography/Milli-whistle technique for