Chapter 5 Conclusion and suggestion
5.2 Suggestion
Herein, looking for underlying or comorbid sleep problems in any child who presents with inadequately-controlled asthma is an important issue before deciding the new strategy for asthma management (such as adding anti-inflammatory agents or increasing the dosage of anti-inflammatory agents). Achieving good sleep could become a therapeutic option to enhance the success in the management of diseases that are characterizedby TH2 cytokine predominance, such as atopic asthma. Thus, it can be anticipated that further insight into thefunctional role of cytokines on sleep quality of asthmatic sufferers will result in novel therapeutic perspectives.
Nonetheless, more research is warranted to see whether the reduced IL-10 level and elevated IL-12/IL-10 ratio in the good sleepers is of therapeutic benefit. Clinicians should make an effort and do more to shift the spiral to a positive direction by helping asthmatic children to gain well-control of their asthma and get the sleep they need.
Fig 1 Cytokines and total IgE level of the good sleepers (■, n =11) and the poor sleepers (□, n = 57) in the well-controlled group (N = 68). *: p < 0.05
Table 1 Demographic characteristics
Data presented as Mean ± SD
Grade 1: Intermittent, Grade 2: Mild persistent, Grade 3: Moderate persistent
Table 2 Asthma control and laboratory tests Data presented as Mean ± SD
Table 3 Asthma control and subjective sleep quality Inadequately-controlled
(N = 22)
Well-controlled (N = 68)
p value
Sleep disturbance Subjective sleep perception
8.14 ± 7.193 3.95 ± 1.090
4.91 ± 4.203 4.59 ± 1.149
0.063 0.028*
* p < 0.05
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附錄
2 Childhood Asthma Control Test 兒童氣喘控制測驗(4 到 11 歲兒童專用)
3. 氣喘兒童睡眠品質問卷 第一部分
第二部分 基本資料 病歷號碼： 個案編號：
4. 授 權 書
本授權書所授權之「兒童睡眠品質問卷」，乃為本人於國立臺灣大學 護理學研究所，撰寫碩士學位論文過程所自行研發測試之問卷工具。