Karl W K TSIM, Head of Department and Professor H Benjamin PENG, Chair Professor
Yuk-Shan WONG, Professor and Vice-President for Administration and Business Donald C CHANG, Visiting Professor, Professor Emeritus
King L CHOW, Professor Ning LI, Professor
Andrew L MILLER, Professor
Peiyuan QIAN, Professor and Assoc Director, Atmospheric, Marine and Coastal Environment Program; Director, Coastal Marine Laboratory
Wenxiong WANG, Professor Joseph T Y WONG, Professor Yong XIE, Professor
Shain Dow KUNG, Adjunct Professor and Professor Emeritus David K BANFIELD, Associate Professor
Pingbo HUANG, Associate Professor Kevin A W LEE, Associate Professor Hongbin LIU, Assistant Professor
Chi Yan CHOI, Research Assistant Professor Sarah E HO, Research Assistant Professor David T W LAU, Research Assistant Professor Stanley C K LAU, Research Assistant Professor On On LEE, Research Assistant Professor
Karl W K TSIM
Head of Department and Professor (2358 7332 ; [email protected])
PhD, University of Cambridge (1987)
Current Research Activities:
Molecular neurobiology of synaptogenesis; moleular genetic analysis of traditional Chinese medicine (TCM).
Active Projects as Principal Investigator:
Assembly of different forms of AChE in muscles: Probing the functional role of nerve-derived trophic factors and muscular activity
RGC - General Research Fund HK$1,421,087 01 Sep 2007
Probing the action mechanism of paired-herbs in traditional Chinese medicine: a model by using Fo Shou San in revealing the compatibility of Radix Angelica Sinensis and Rhizoma Chuanxiong
RGC - General Research Fund HK$934,922 01 Oct 2008
Integration of chemical and biological approaches for drug discovery
CAS-Croucher Funding Scheme for Joint Laboratories HK$768,000 01 Oct 2008
Integration of chemical and biological approaches for drug discovery
Office of the Dean of Science, HKUST HK$92,000 01 Oct 2008
Integration of chemical and biological approaches for drug discovery
Center for Chinese Medicine R&D, HKUST HK$100,000 01 Oct 2008
Integration of chemical and biological approaches for drug discovery
UGC - Government's Matching Grant Scheme HK$207,200 01 Oct 2008
Delineating the action mechanism of Danggui Buxue Tang (A Chinese angelica decoction): A sample trial in understanding the efficacy of traditional Chinese medicine
Germany / Hong Kong Joint Research Scheme HK$30,000 01 Jan 2009
Searching for distinctions among roots of panax ginseng, panax quinguefolius and panax notoginseng: approaches by using proteomic, biological and chemical analyses
National Natural Science Foundation of China / Research Grants Council Joint Research Scheme HK$533,000 01 Jan 2008 Novel dimeric AChE inhibitors: Signaling mechanisms of neuroprotections against excitotoxins associated with Alzheimer's disease
RGC - General Research Fund HK$121,000 01 Nov 2007
Novel dimeric AChE inhibitors: Cellular and molecular characterization of one-compound-multi-targets at soluble amyloid cascade associated with Alzheimer's Disease
RGC - General Research Fund HK$470,000 01 Nov 2007
Representative Research Publications:
Li, Jun, Li, Zhuoming, Huang, Wen, Cheung, Wing Han, Bi, Wenchuan, Duan, Ran, Guo, Jiangyang, Dong, Tingxia, Tsim, Karl W K (2009) "Quality evaluation of Rhizoma Belamcandae (Belamcanda chinensis (L.) DC.) by using high-performance liquid chromatography coupled with diode array detector and mass spectrometry.", J Chromatogr A., 1216(11):2071-2078.
Leung, Ka Wing, Xie, Qunhui, Chen, Ping, Mok, Ka Wai, Chu, Kin Yan, Choi, Chi Yan, Tsim, Karl W K (2009)
"Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions--contribution and expression from motor neurons", FEBS J., 276(11):3031-3042.
Guo, Jiangyang, Choi, Chi Yan, Cheung, Wing Han, Li, Jun, Chen, Xiaoying, Dong, Tingxia, Tsim, Karl W K (2009) "Stimulation of Apolipoprotein A-IV expression in Caco-2/TC7 enterocytes and reduction of triglyceride formation in 3T3-L1 adipocytes by potential anti-obesity Chinese herbal medicines.", Chin Med., 4:5-10.
Xie, Qunhui, Choi, Chi Yan, Leung, Ka Wing, Chen, Ping, Chu, Kin Yan, Tsim, Karl W K (2009) "Transcriptional regulation of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in neuron: an inductive effect of neuron differentiation.", Brain Res., 1265:13-23.
Lau, Faye, Choi, Chi Yan, Xie, Qunhui, Leung, Ka Wing, Chen, Ping, Zhu, Tingting, Bi, Wenchuan, Chu, Kin Yan, Tsim, Karl W K (2008) "Myocyte enhancer factor 2 mediates acetylcholine-induced expression of acetylcholinesterase-associated collagen ColQ in cultured myotubes.", Mol Cell Neurosci., 39(3):429-438.
Choi, Chi Yan, Mok, Ka Wai, Cheung, Wing Han, Siow, Lam, Xie, Qunhui, Tsim, Karl W K (2008) "Regulation of
PRiMA-linked G(4) AChE by a cAMP-dependent signaling pathway in cultured rat pheochromocyoma PC12 cells.", Chem Biol Interact., 175(1-3):76-78.
Xie, Qunhui, Leung, Ka Wing, Chen, Ping, Lau, Faye, Liu, Sili, Choi, Chi Yan, Tsim, Karl W K (2008) "The promoter activity of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase in muscle: suppressive roles of myogenesis and innervating nerve.", Chem Biol Interact., 175(1-3):79-82.
Tsim, Karl W K, Choi, Chi Yan, Xie, Qunhui, Zhu, Tingting, Leung, Ka Wing, Lau, Faye, Chu, Kin Yan, Chen, Ping, Mok, Ka Wai, Cheung, Wing Han, Bi, Wenchuan (2008) "Transcriptional control of different subunits of AChE in muscles: signals triggered by the motor nerve-derived factors.", Chem Biol Interact., 175(1-3):58-63.
H Benjamin PENG Chair Professor
(2358 7302 ; [email protected])
PhD (1976) and Postdoctoral Fellow (1976-78) Purdue University
Assistant Professor to Associate Professor, University of Illinois College of Medicine (1978-85)
Associate Professor to Full Professor, School of Medicine, University of North Carolina at Chapel Hill (1985-2000) Current Research Activities:
Molecular and cellular neuroscience; cell biology; developmental biology.
Active Projects as Principal Investigator:
Regulation of presynaptic differentiation and synapse formation by p120 catenin
RGC - General Research Fund HK$649,765 01 Jan 2009
Signal-induced surface trafficking of receptors
RGC - General Research Fund HK$1,723,500 01 Jan 2007
Representative Research Publications:
Qian, Y.K., Chan, Ariel W S, Madhavan, Raghavan, Peng, Benjamin H (2008) "The function of Shp2 tyrosine phosphatase in the dispersal of acetylcholine receptor clusters", BMC Neuroscience, 9:70 (17 pages).
Lee, CW, Peng, HB (2008) "The function of mitochondria in presynaptic development at the neuromuscular junction", Mol Biol Cell, 19(1):150-8.
Geng, L, Qian, YK, Madhavan, R, Peng, HB (2008) "Transmembrane mechanisms in the assembly of the postsynaptic apparatus at the neuromuscular junction", Chem Biol Interact, Apr 24. [Epub ahead of print].
Zhao, XT, Qian, YK, Chan, AW, Madhavan, R, Peng, HB (2007) "Regulation of ACh receptor clustering by the tyrosine phosphatase Shp2", Dev Neurobiol, 67(13):1789-801.
Madhavan, Raghavan, Peng, H.Benjamin (2006) "HGF induction of postsynaptic specializations at the neuromuscular junction.", J. Neurobiol., 66:134-147.
Madhavan, Raghavan, Zhao, Xiaotao T., Reynolds, A.B., Peng, H.Benjamin (2006) "The involvement of p120 catenin in myopodial assembly and nerve-muscle synapse formation", J. Neurobiol., 66:1511-1527.
Madhavan, Raghavan, Peng, H. Benjamin (2006) "HGF induction of postsynaptic specializations at the neuromuscular junction", J. Neurobiol, 66:134-147.
Geng, Lin, Peng, H. Benjamin (2005) "Visualization of ACh receptor clustering with quantum dots. Program No. 369.2. Abstract Viewer/Itinerary Planner.", Washington DC: Society for Neuroscience., 12-16 Nov 2005.
Yuk-Shan WONG
Professor and Vice-President for Administration and Business
(2358 6151 ; [email protected] ; http://www.ust.hk/~webbo/faculty/Prof.Y.S.Wong/index.html)
PhD, McGill University (1979)
Vice-President (Administration) (2002-06), Professor (Chair) of Biological Sciences, Department of Biology and
Chemistry (1998-06), Vice-President (Institutional Advancement) (1998-02), CityU; Associate Vice-President (Research & Development) (1997-98), Associate Director, Research Centre (1993-97), HKUST; Principal Lecturer and Head of Department of Applied Biology & Chemical Technology, HK PolyU (1988-90); Lecturer, Department of Biology, CUHK (1985-88); Lecturer, Department of Applied Science, HK PolyU (1980-85); Medical Research Council Post-doctoral Fellow, Banting & Best Institute for Medical Research, University of Toronto (1979-80).
Current Research Activities:
Environmental biotechnology, plant biochemistry and physiology.
Representative Research Publications:
Tam, N.F.Y., Wong, Y.S. (2008) "Effectiveness of Bacterial Inoculum and Mangrove Plants on Remediation of Sediment Contaminated with Polycyclic Aromatic Hydrocarbons", Marine Pollution Bulletin, 57: 716-726.
Chen, J.L., Wong, M.H., Wong, Y.S., Tam, N.F.Y. (2008) "Multi-factors on Biodegradation Kinetics of Polycyclic Aromatic Hydrocarbons (PAHs) by Sphingomonas sp., a Bacterial Strain Isolated from Mangrove Sediment", Marine Pollution Bulletin, 57: 695-702.
Han, X., Wong, Y.S., Wong, M.H., Tam, N.F.Y. (2007) "Biosorption and Bioreduction of Cr(VI) by a Microalgal Isolate, Chlorella miniata", Journal of Hazardous Materials, 146: 65-72.
Zhang, C.G., Leung, K.K., Wong, Y.S., Tam, N.F.Y. (2007) "Germination, Growth and Physiological Responses of Mangrove Plant (Bruguiera gymnorrhiza) to Lubricating Oil Pollution", Environmental and Experimental Botany, 60: 127-136.
Lei, A.P., Hu, Z.L., Wong, Y.S., Tam, N.F.Y. (2007) "Removal of Fluoranthene and Pyrene by Different Microalgal Species", Bioresource Technology, 98: 273-280.
Luan, T.G., Jin, J., Chan, S.N.N., Wong, Y.S., Tam, N.F.Y. (2006) "Biosorption and Biodegradation of Tributyltin (TBT) by Alginate Immobilized Chlorella vulgaris Beads in Several Treatment Cycles.", Process Biochemistry, 41: 1560-1565.
Zhou, H.W., Guo, C.L., Wong, Y.S., Tam, N.F.Y. (2006) "Genetic Diversity of Dioxygenase Genes in Polycyclic Aromatic Hydrocarbon-degrading Bacteria Isolated from Mangrove Sediments.", FEMS Microbiology Letters, 262: 148-157.
Han, X., Wong, Y.S., Tam, N.F.Y. (2006) "Surface Complexation Mechanism and Modeling in Cr (III) Biosorption by a Microalgal Isolate, Chlorella miniata.", Journal of Colloid and Interface Science, 303: 365-371.
Donald C CHANG
Visiting Professor, Professor Emeritus
(2358 7326 ; [email protected] ; http://ihome.ust.hk/~changlab/)
PhD, Rice University (1970)
Summer Investigator, Marine Biological Laboratory at Woods Hole (1976-94) Associate Professor, Baylor College of Medicine (1985-91)
Chair Professor (2006-08) and Professor (1991-2006), Hong Kong Univeristy of Science and Technology Current Research Activities:
Molecular biophysics; calcium signaling; cellular structure and function by laser microscopy; mechanisms of cell division and apoptosis;
gene transfer and cell fusion using an electric field.
Representative Research Publications:
Zhou, LY, Chang, Donald C. (2008) "Dynamics and structure of the Bax-Bak complex responsible for releasing mitochondrial proteins during apoptosis", J Cell Sci., 121(Pt 13):2186-96.
Yin, YL, Yu, Vivian C., Zhu, G., Chang, Donald C. (2008) "SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail", Cell Cycle, 7(10):1423-32.
Tian, Honglei, Ip, Louisa, Luo, Houwei, Chang, Donald Choy, Luo, Kathy Qian (2007) "A high throughput drug screen based on fluorescence resonance energy transfer (FRET) for anti-cancer activity of compounds from herbal medicine.", British Journal of Pharmacology, 150: 321-334.
Xu, N.H., Chang, D.C. (2007) "Different thresholds of MPF inactivation are responsible for controlling different mitotic events in mammalian cell division", Cell Cycle, 6(13):1639-1645.
Zhou, L.L., Zhou, L.Y., Luo, K.Q., Chang, D.C. (2005) "Smac/DIABLO and Cytochrome c are released from mitochondria through a similar mechanism during UV-induced apoptosis", Apoptosis, 10:289-299.
Luo, Kathy Q., Chang, Donald C. (2004) "The gene-silencing efficiency of siRNA is strongly dependent on the local structure of mRNA at the targeted region", Biochem Biophys Res Comm, 318:303-310.
Chang, Donald C., Xu, Naihan, Luo, Kathy Q. (2003) "Degradation of cyclin B is required for the onset of anaphase in mammalian cells", J. Biol. Chem, 278:37865-37873.
Gao, Wenhua, Pu, Yongmei, Luo, Kathy Qian, Chang, Donald C. (2001) "Temporal relationship between cytochrome c release and mitochondrial swelling during UV-induced apoptosis in living HeLa cells", Journal of Cell Science, 114: 2855-2862.
King L CHOW Professor
(2358 7342 ; [email protected])
PhD, Baylor College of Medicine (1990)
Research Associate, Molecular Genetics, Albert Einstein College of Medicine
Current Research Activities:
Pattern formation and differentiation of sensory organ; tissue remodeling and morphogenesis; unfolded protein response; functional genomics, chemosensory perception circuitry, pheromone, evolution of mating system.
Active Projects as Principal Investigator:
In vivo analysis of Mab21 function in retinal development and its regulatory interaction with conserved genetic components
RGC - General Research Fund HK$1,085,729 20 Dec 2007
Cellular and molecular characterization of pheromone perception in Caenorhabditis
RGC - General Research Fund HK$1,510,186 01 Jan 2009
Developmental genomics & skeletal research
UGC - Areas of Excellence HK$3,576,550 21 Apr 2004
Genomic approaches to uncover functionally relevant signalling pathways in craniofacial development
RGC - Collaborative Research Fund HK$570,000 01 Jul 2006
Sustained synthetic biology education in Hong Kong (SynBioHK)
Croucher Foundation HK$325,000 01 Jul 2009
Sustained synthetic biology education in Hong Kong (SynBioHK)
UGC - PDF Matching Fund HK$156,000 01 Jul 2009
Studying the role of Mab21 in neural development by generating and analysis transgenic mice ectopically expressing Mab21 gene
UGC - Government's Matching Grant Scheme HK$27,500 01 Jul 2008
Centre for MicroRNA Study - basic research and clinical potentials in cancer
RGC - Collaborative Research Fund HK$285,000 01 Apr 2009
Studying the role of Mab21 in neural development by generating and analysing transgenic mice ectopically expressing Mab21 gene
Kai Chong Tong HK$550,000 01 Jul 2008
Representative Research Publications:
Tsang, Wai Hung, Chow, King Lau (2009) "Mouse embryo cryopreservation utilizing a novel high-capacity vitrification spatula.", Biotechniques, 46:468-472.
Lin, Liwen, Chow, King Lau, Leng, Yang (2009) "Study of hydroxyapatite osteoinductivity with an osteogenic differentiation assay using mesenchymal stem cells.", J Biomaterial Res., 89: 326-335.
Tang, Cemun, Chow, King Lau (2008) "Discovery-based functional genomics laboratory for Biology Program.", Practice and Evidence of the Scholarship of Teaching and Learning in Higher Education., 3: 57-67.
Tsang, SW, Nguyen, CQ, Hall, DH, Chow, KL (2007) "MAB-7 is a novel transmembrane protein that orchestrates C. elegans sensory ray morphogenesis", Developmental Biology, 312: 353-366.
Wong, YF, Ko, CF, Cheah, KSE, Chow, KL (2007) "crm-1 facilitates BMP signaling to control the body size in C. elegans", Developmental Biology, 311:95-105.
Choy, SW, Wong, YM, Ho, SH, Chow, KL (2007) "C. elegans SIN-3 and its associated HDAC corepressor complex act as mediators of male sensory ray development", Biochem. Biophy. Res. Comm., 358:802-807.
Chasnov, JR, Chan, CM, So, WK, Chow, KL (2007) "The species, sex, and stage specificity of a Caenorhabditis sex pheromone", Proc. Nat. Acad. Sci. USA, 104: 6730-6735.
Ko, Frankie C.F., Chow, King L. (2003) "A mutation at the start codon defines the differential requirement of dpy-11 in Caenorhabditis elegans body hypodermis and male tail", Biochem. Biophy. Research Comm., 309, 201-208.
Ning LI Professor
(2358 7335 ; [email protected])
PhD, University of Washington (1989)
Research Associate, USDA/ARS/PSI Plant Molecular Biology Laboratory (1989-93)
Current Research Activities:
Phosphoproteomics in plant cell signal transduction; Molecular biology of phenylpropanoids; genetic engineering of energy plants and microbes.
Active Projects as Principal Investigator:
A multi-disciplinary interactome approach to the study of post-translational regulation of ACC synthase gene expression in the model plant arabidopsis
RGC - General Research Fund HK$1,276,493 20 Aug 2007
Functional phosphoproteome analysis of the rapid inhibitory effect of ethylene on shoot negative gravitropism of Arabidopsis
RGC - General Research Fund HK$831,365 09 Sep 2008
Investigation of upstream ethylene signaling components via novel approaches
National Natural Science Foundation of China / Research Grants Council Joint Research Scheme HK$672,300 01 Dec 2006
Representative Research Publications:
Qing, Dong-Jin, Lu, Hai-Feng, Li, Ning, Dong, Hai-Tao, Dong, Deng-Feng, Li, You-Zhi (2009) "Comparative Profiles of Gene Expression in Leaves and Roots of Maize Seedlings under Conditions of Salt Stress and the Removal of Salt Stress", Plant and Cell Physiology, 50, 889-903.
Li, Hao, Wong, Wai Shing, Guo, Hong Wei, Ecker, Joseph, Li, Ning (2009) "Phosphoproteomics analysis of ethylene-regulated protein phosphorylation in etiolated seedlings of Arabidopsis mutant ein2 using 2-D-separations coupled with a hybrid Q-TOF mass spectrometry", Proteomics, 9, 1646-1661.
Guo, Di, Gao, Xiaorong, Li, Hao, Zhang, Tao, An, Lijia, Li, Ning (2008) "EGY1 plays a role in regulation of endodermal plastid size and number that are involved in ethylene-dependent gravitropism of light-grown Arabidopsis hypocotyls", Plant Molecular Biology, 66, 345-360.
Li, Ning (2008) "The dual-and-opposing-effect of ethylene on the negative gravitropism of Arabidopsis inflorescence stem and light-grown hypocotyls", Plant Science, 175, 71-86.
Chen, Gu, Wang, Xiaoli, Wong, Waishing, Li, Ning (2005) "Application of 3' untranslated region (UTR) sequence-based amplified polymorphism analysis in rapid authentication of Radix Astragali.", Journal of Agricultural and Food Chemistry, 53, 8551-8556.
Chen, Gu, Bi, Yurong, Li, Ning (2005) "EGY1 encodes a membrane-associated and ATP-independent metalloprotease that is required for chloroplast development.", The Plant Journal, 41, 363-375.
Wong, Waishing, Guo, Di, Wang, Xiaoli, Yin, Zhiqi, Li, Ning (2005) "Study of cis-cinnamic acid in Arabidopsis thaliana.", Plant Physiology & Biochemistry, 43, 929-937.
Mehta, R.A., Cassol, T., Li, Ning, Ali, N., Handa, A.K., Mattoo, A.K. (2002) "Engineered polyamine accumulation in tomato enhances phytonutrient content, juice quality and vine life", Nature Biotechnology, 20, 613-618.
Andrew L MILLER Professor
(2358 8631 ; [email protected])
PhD, University of Dundee (1986)
Principal Investigator, Marine Biological Laboratory, Woods Hole (1992-95)
Current Research Activities:
Calcium signaling during early development; calcium imaging techniques; transgenic model systems for imaging calcium ions in living organisms.
Active Projects as Principal Investigator:
Investigating the role of calcium signaling during the blastula period of zebrafish development
RGC - General Research Fund HK$1,322,154 01 Aug 2007
Hong Kong Joint Universities Summer Teaching Laboratory (JUSTL)
Croucher Foundation HK$1,106,118 01 Aug 2006
Hong Kong Joint Universities Summer Teaching Laboratory (JUSTL)
UGC - Government's Matching Grant Scheme HK$1,106,118 01 Aug 2006
Establishment of a multi-application microscopy suite (MAMS) at HKUST
UGC Miscellaneous HK$8,232,000 01 Oct 2008
Establishment of a multi-application microscopy suite (MAMS) at HKUST
UGC - Special Equipment Grant HK$9,400,000 01 Oct 2008
An Associated International Laboratory (LIA) - Role of calcium in cellular determination and differentiation (ROCADE)
VPRD Research Discretionary Fund HK$80,000 01 Jul 2008
Representative Research Publications:
Ma, Leung Hang, Webb, Sarah, Chan, Ching Man, Zhang, Jiao, Miller, Andrew L (2009) "Establishment of a transitory dorsal-biased window of localized Ca2+ signaling in the superficial epithelium following the mid-blastula transition in zebrafish embryos.", Developmental Biology, 327:143-157.
Lam, Pui Ying, Webb, Sarah, Leclerc, Catherine, Moreau, Marc, Miller, Andrew L (2009) "Inhibition of stored Ca2+ release disrupts convergence-related cell movements in the lateral intermediate mesoderm resulting in abnormal positioning and morphology of the pronephric anlagen in intact zebrafish embryos.", Development, Growth & Differentiation, 51: 429-442.
Webb, Sarah, Li, Wai Ming, Miller, Andrew (2008) "Calcium signalling during the cleavage period of zebrafish development", Philosophical Transactions of the Royal Society B, 363, 1363-1369.
Li, Wai Ming, Webb, Sarah, Chan, Ching Man, Miller, Andrew (2008) "Multiple roles of the furrow deepening Ca2+
transient during cytokinesis in zebrafish embryos", Developmental Biology, 315, 228-248.
Webb, Sarah, Miller, Andrew (2007) "Ca2+ signaling during embryonic cytokinesis in animal systems", New Comprehensive Biochemistry. Calcium: A matter of life or death, Vol 41, Ch. 17, pp 445-470.
Webb, Sarah, Miller, Andrew (2007) "Ca2+ signaling and early embryonic patterning during zebrafish development", Proceedings of the Australian Physiological Society, 38: 43-51.
Webb, Sarah, Miller, Andrew (2006) "Ca2+ signaling and early embryonic patterning during the Blastula and Gastrula Periods of zebrafish and Xenopus development", Biochimica et Biophysica Acta, 1763:1192-1208.
Webb, Sarah, Miller, Andrew (2003) "Calcium signalling during embryonic development", Nature Reviews Molecular Cell Biology, 4: 539-551.
Peiyuan QIAN
Professor and Assoc Director, Atmospheric, Marine and Coastal Environment Program; Director, Coastal Marine Laboratory
(2358 7331 ; [email protected])
PhD, University of Alberta (1991)
Current Research Activities:
Larval ecology; anti-fouling; marine aquaculture; benthic ecology; marine natural products.
Active Projects as Principal Investigator:
Chemical cues produced by NATURAL biofilms with different attractiveness for the larval settlement of major fouling organisms
RGC - General Research Fund HK$984,259 01 Jan 2008
Comparative proteomic analysis of settling and metamorphosing larvae of two major fouling organisms challenged by natural antifoulants/settlement cues
RGC - General Research Fund HK$871,044 01 Jan 2009
Low/non-toxic antifouling compounds from marine extremophiles and development of antifouling paints
China Ocean Mineral Resources R&D Association HK$1,401,750 01 Jul 2007
Biofouling/ antifouling research
UGC - Government's Matching Grant Scheme HK$8,943 01 Oct 2008
Genes involved in larval attachment and metamorphosis of a major biofouling worm Hydroides elegans
RGC - General Research Fund HK$1,229,500 01 Jan 2007
Centre for marine environmental research and innovative technology (MERIT)
Office of the President, HKUST HK$1,000,000 01 Apr 2004
Biofouling/ antifouling research
Rohm and Haas Co. HK$179,400 01 Oct 2008
Large scale fermentation of marine antifouling microorganisms and efficient extraction of their active antifouling ingredients
Shenzhen Bureau of Science Technology & Information HK$163,537 17 May 2008
Centre for marine environmental research and innovative technology (MERIT)
Office of the Vice-President for Academic Affairs, HKUST HK$600,000 01 Apr 2004
Representative Research Publications:
Wong, Yue Him Tim, Qian, Peiyuan, Thiyagarajan, V (2009) "2D gel-based proteome and phosphoproteme analysis during larval metamorphosis in two major marine biofuling invertebrates.", J Proteome Res, 8:2708-2719.
Lee, On On, Chung, Hong Chun Gary, Qian, Peiyuan, Hung, OS, Thiyagarajan, V, He, HP, Xu, Ying, Qiu, JW (2009)
"Characterization of cues from natural multi-species biofilms to induce larval attachment of the polychaete Hydroides elegans.", Aquatic Biol, 4: 253-262.
Qian, Peiyuan, Ki, JS, Zhang, W (2009) "Discovery of marine Bacillus species by 16s rRNA and rpoB comparison and their usefulness for species identification.", J Microbiol Methods, 77:48-59.
Lee, On On, Qian, Peiyuan, Huang, YL, Ki, JS (2009) "Evidence for the dynamics of acyl homoserine lactone based quorum sensing during early subtidal biofilm formation.", ISMEJ, 3: 296-304.
Lee, On On, Wong, Yue Him Tim, Qian, Peiyuan (2009) "Inter- and intra-specific variations of bacterial communities associated with marine sponges from the San Juan Island, Washington, USA.", Appl Environ Microbiol, 75: 3513-3521.
Qian, Peiyuan, Li, HL, Song, LS (2008) "Cyclic AMP concentration and protein kinase A (PKA) gene expression at different developmental stages of the polychaete Hydroides elegans.", J Exp. Zool (Mol. Dev. Evol.), 310B: 417-427.
Qian, Peiyuan, Zhang, R, Thiyagarajan, V (2008) "Evaluation of terminal-restriction fragment length polymorphism analysis in contrasting marine environments.", FEMS Microbial Ecol., 65, 169-178.
Qian, Peiyuan, Thiyagarajan, V (2008) "Proteome analysis of larvae during development, attachment and metamorphosis in the fouling barnacle Balanus amphitrite.", Proteomics, 8: 3164-3172.
Wenxiong WANG
Professor
(2358 7346 ; [email protected] ; http://www.ust.hk/~webbo/faculty/Prof.W.Wang/index.html)
PhD, State University of New York at Stony Brook (1996) Visiting Researcher, Plymouth Marine Laboratory, UK (1989-91)
Current Research Activities:
Metal ecotoxicology and biogeochemistry; marine pollution; physiological ecology.
Active Projects as Principal Investigator:
Growth-dependent mercury exposure in marine fish and plankton
RGC - General Research Fund HK$1,195,046 01 Jul 2009
Center for metals in the marine environment (CMME)
RGC - Collaborative Research Fund - Seed Funding HK$250,000 29 May 2007
Mercury contamination in freshwater and marine fish cultivated around the Pearl River Delta, and its health risk assessment
RGC - Collaborative Research Fund HK$200,000 01 Jun 2008
Understanding toxic metal concentrations in important marine shellfish in Hong Kong
RGC - General Research Fund HK$1,229,500 01 Jul 2006
Metals in the marine environment: bioaccumulation, toxicity, and risk assessment
Metals in the marine environment: bioaccumulation, toxicity, and risk assessment