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指導醫師:口腔病理科全體醫師 Intern I

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(1)

Intern I

指導醫師:口腔病理科全體醫師

(2)

Name:王XX

No. of Chart :2xxxxx8 Gender:Male

Age: 43 y/o Occupation : 工

Address : 屏東縣屏東市

Date of first visit : 100/04/04

(3)

A swelling mass over lower anterior teeth

(4)

This 43 y/o male was transferred to our

emergent department(ED) for help due to rapid progression of neck pain and abdomen

extension. At our ED, the initial vital sign listed below: BP:120/87mmHg HR:110 RR:20 BT:37.5.

The general survey was done, and the

Abdomen CT and Chest CT revealed bilateral halar and subscarina lymph node and right

lower lobe pneumonia or atlactasis with ascites, bilateral liver lobe multiple metastasis and

suspect carcinomatosis from the infiltrated

peritonium with pleural effusion ,with 4th rib metastasis.

He also got the lower ginigiva hypertrophy and

swelling with local redness, so 肝膽內科 consulted our 口腔外科 for help

(5)

Disease history:

- alcoholic impaired liver function for many years

- Asthma(denied)

Diabetes mellitus: denied Hypertension: denied

HBV/HCV: denied/denied

Coronary heart disease: (denied)

Ischemiac/hemoragic stroke: (denied)/(denied) Operation history: for right ankle laceration

Hospitalization: for right ankle laceration

(6)

Attitude to dental treatment:cooperative

(7)

Alcohol drinking (+)

- 2 bottle bear and some 高粱 for more than 10 years with quiting for several years

Betel nut chewing (-) Cigarette smoking (+)

- 2 PDD for more than 20 years Denied other specific habit

(8)

A swelling over labial gingiva of tooth 31-41, red, polypoid, firm,

pedunculate,

smooth surface, measured

1.5X0.7cm

(9)

Inflammation Neoplasm

(10)

Our case Inflammation Cyst Neoplasm

Color Red Red Normal Variable

Discharge - + - -

Consistency Firm Rubbery Soft Firm

Pain - + - +/-

Ulceration - - - +/-

Mobility Fixed Fixed Fixed Fixed

Duration ? Days Years Months

(11)

Benign Malignant

Inflammation Cyst Neoplasm

(12)

Malignant neoplasm

- Metastases to the oral soft tissues

- Adenosquamous carcinoma

- Karposi’s sarcoma

Benign neoplasm

- Peripheral giant cell granuloma

- Peripheral ossifying fibroma

Pseudo-tumor

- Pyogenic granuloma

(13)

Metastases to the oral soft tissues

Adenosquamous carcinoma

Karposi’s sarcoma

(14)

0.25% of all oral malignancies

Most common site is gingiva(50%), tongue(25%)

Usually appears as a nodular mass

Male: lung cancer 1/3,followed by renal carcinoma and melanoma

Female: breast cancer 1/4, followed by

malignancies of genital organs, lung, bone and kidney

In most cases, primary tumor already is known when the metastatic lesion is discovered.

(15)

Our case Metastases to the oral soft tissues

Gender M M

Age 43 Middle-age and older

adult

Site Gingiva Gingiva (50%)

Pain - +/-

Ulcer - +/-

LAP + +

Consistency firm firm

Shape Polypoid mass Nodular/polypoid

mass

Features Smooth surface 1% of all oral malignancies

(16)

rare variant of SCC

combination of SCC and adenocarcinoma

adenoid pattern (glandular)

80% metastatic deposit, neck nodes

high grade mucoepidermoid carcinoma

older people

tongue oral floor mucosa

(17)

Our case Adenosquamous carcinoma

Gender M -

Age 43 Middle-age and older

adult

Site Gingiva tongue oral floor

mucosa

Pain - -

Ulcer - -

LAP + +

Consistency firm firm

Shape Polypoid mass -

Features Smooth surface combination of SCC and adenocarcinoma

(18)
(19)

Our case Immunodeficien cy type

Gender M -

Age 43 teenager

Site Gingiva Skin , mucosa ,

visceral organ

Pain - +

Ulcer - +/-

LAP + -

Consistency firm rubbery

Shape Polypoid mass nodule

Features Smooth surface aggresive

(20)

Peripheral giant cell granuloma

Periphery ossifying fibroma

(21)

Case by local irritation or trauma

60% in female

Usually smaller than 2 cm in diameter

Mandible is affected slightly more often than maxilla

Tx: local surgical excision down to the underlying bone

(22)

Our case Peripheral giant cell granuloma

Gender M F(60%)

Age 43 50-60 y/o

Site Gingiva 1st molar 之

前 ,incisor 之間 gingiva

Pain - -

Ulcer - +/-

LAP + -

Consistency firm soft

Shape Polypoid mass Sessile or pedunculated Features Smooth surface

(23)

Exclusively on gingival,slightly maxilla, emanate from interdental papilla

nodular mass,peduculate/sessile

red to pink,about 2 cm

Teenager ,2/3 female

(24)

Our case Periphery

ossifying fibroma

Gender M F(2/3)

Age 43 teenager

Site Gingiva gingiva

Pain - -

Ulcer - -

LAP + -

Consistency firm rubbery

Shape Polypoid mass

nodular mass Peduculate/

sessile

Features Smooth surface from interdental papilla

(25)

Metastasis to the oral soft tissues over labial gingiva of tooth 41,42

(26)

Adenocarcinoma, metastatic over labial gingiva of lower anterior teeth (41,42)

參考文獻

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