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口腔病理科 On-Line KMU Student Bulletin

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原文題目(出處): Glomus tumor of the cheek: A case report. Case Reports in Medicine 2012, article ID 307294

原文作者姓名: KonstantinosVeros, KonstantinosMarkou, Chrysa Filitatzi, andDionysios E.Kyrmizakis

通訊作者學校: 1st Department of Otorhinolaryngology Head & Neck Surgery, AHEPA University Hospital, 54006 Thessaloniki, Greece

Department of Pathology, Department of Otorhinolaryngology Head & Neck Surgery, General Hospital of Veroia, 59100 Veroia, Greece

報告者姓名(組別): 紀勝元 Intern L 組

報告日期: 2012/08/06

內文:

Introduction

* Glomus tumor:

- called paraganglioma

- benign neoplasm of perivasculature - 1~2% of soft tissue tumors

- 3% metastasis

- painful subcutaneous nodules in subungual area of digits - rare in cheek

- symptoms: pain ,localized tenderness, cold, Hypersensitivity Case report

* 24-year-old man with a four-year painful nodule in left cheek that reoccurred after two excisions in the last four months

* Clinical examination:

- well-defined ,round ,firm nodule - 1 x 1 cm

- subdermic

- without fixation to underlying tissues - painful on palpation

- normal oral cavity

- no neck lymph nodes be palpated

* Contrast enhanced CT:

- well-defined, round soft-tissue mass of left cheek over buccinator muscle

- measuring 13.8 x 9 mm

- a very small satellite lesion attached

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口腔病理科 On-Line KMU Student Bulletin

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* After relatively wide excision, specimen was consistent with diagnosis of glomus tumor of the solid type, with no mention of potential residual disease

* Patient reported relief of symptoms after surgery

* 2-month follow-up :

- complained of gradual recurrence of local tenderness at the site of the excision

* Three months later :

- small palpable nodule and complete recurrence of symptoms

* Very wide excision performed :

- 1 cm margin around the previous scar

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口腔病理科 On-Line KMU Student Bulletin

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Solid : Angiomatoid :

Angiomyomatous :

* Histological examination :

- margins of the excision were reported as free of lesion

* Patient remains without any symptoms nine months after surgery

* Glomus body:

- neuromyoarterial unit found within reticular dermis that serves as a specialized arteriovenous anastomosis

- arterial end of glomus body(Sucquet-Hoyer) surrounded by modified smooth muscle cells

called glomus cells →regulate blood flow to skin in response to temperature changes

* Variantts of glomus tumor

1. Solid: poor vasculature, scant smooth muscle component 2. Angiomatoid(Glomangioma): predominant vascular component

3. Glomangiomyoma: prominent vasculature and smooth muscle components

* Glomus tumors:

- Mostly solitary masses

- Malignant transformation extremely rare (3%)

- Most commonly in upper extremity , especially in subungual area - Facial location , especially in cheek is rare

Discussion

* Facial glomus tumor:

- asymptomatic subcutaneous nodule rarely - may be excruciating chronic facial pain

- long history of consultations by various specialists

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口腔病理科 On-Line KMU Student Bulletin

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without a definite diagnosis can be expected - pain , localized tenderness

- cold hypersensitivity may or may not

- 4:1 male predominance(extradigital glomus tumor)

* MRI the most sensitive imaging modality for diagnosis

Contrast enhanced CT aid in differential diagnosis and delineating anatomic relations for operation

* Small size and subcutaneous location → complete removal treatment as choice

* Excellent results anticipated - recurrence rates (12%~33%)

題號 題目

1 What’s location does glomus tumor mostly occur ? (A) Upper Extremity

(B) Lower extremity (C) Abdomen (D) thorax 答 案

( A)

出處:

Glomus Tumor of the Cheek: A Case Report KonstantinosVeros, KonstantinosMarkou, Chrysa Filitatzi, Dionysios E.Kyrmizakis. Hindawi Publishing Corporation Case Reports in Medicine Volume 2012, Article ID 307294, doi:10.1155/2012/307294

題號 題目

2 What percentage of all soft tissue tumors does glomus tumor account for ? (A) 20%~25%

(B) 35%~37%

(C) 8%~10%

(D) 1%~2%

答 案 (D )

出處:

Glomus Tumor of the Cheek: A Case Report

KonstantinosVeros, KonstantinosMarkou, Chrysa Filitatzi, Dionysios E.

Kyrmizakis. Hindawi Publishing Corporation Case Reports in Medicine Volume 2012, Article ID 307294, doi:10.1155/2012/307294

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