Indica rice and exogenous cholesterol with or without hypercholesterolemia cholesterol metabolism in rats
Effects of indica rice and exogenous cholesterol on cholesterol metabolism in rats with or without hypercholesterolemia
Abstract
This study investigated the long rice (Taichung Native 1) of polished rice and brown rice as the carbohydrate source on Rat Serum
And liver cholesterol of the impact of TSE. Wistar male rats to 84 (?
370g) were randomly divided into 7 groups (1
Control, 6 experimental). To feed no cholesterol (0% w / w) corn starch as the control group rats, and the remaining six real
No experience or high intake group, respectively (1% w / w)
cholesterol, corn starch, refined white rice and brown rice diet for 4 weeks (solid
Experience Ⅰ), collecting the last 7 days stool, take half of any rats in each group the serum and liver samples. Rest
Rats continue to raise, in addition to the control group, the original intake of cholesterol-free experimental group fed high-cholesterol diet change; original
Intake of high cholesterol in the experimental group fed no cholesterol diet change, and then to 5 weeks the feeding and collection of samples (experimental Ⅱ
). Fecal dry weight, serum total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipid
Protein cholesterol (HDL-C), triglycerides (TG), phospholipids and liver TC, TG and total lipid (TL). Feed fine white
Groups and fed brown rice dry weight in feces were significantly higher than the feeding of corn starch group. Ⅰ in experimental rats fed the cholesterol-free
, Fed polished rice group HDL-C / LDL-C significantly higher than controls; feeding brown rice serum TG concentrations were
significantly lower than the control group
. Ⅰ in experimental rats fed cholesterol, the corn starch group and feed, feeding groups and fed polished rice can be brown group
Significantly decreased serum TC, LDL-C levels and liver TC and TL concentration can significantly improve HDL-C / LDL-C ratio, only
Feeding significantly reduced serum TG brown group concentration.
In the experiment Ⅱ in rats fed cholesterol, the group compared with the feeding of corn starch
More, feeding groups and fed polished white rice brown rice group can significantly enhance the HDL-C / LDL-C ratio, and significantly decreased serum TC
, LDL-C and liver concentrations of TC and TL; only feed brown rice group could significantly reduce serum TG concentration. No
cholesterol feeding experiment Ⅱ
Rats in comparison with the feeding of corn starch groups, feeding groups and fed polished white rice brown rice group can significantly enhance the HDL-C / LDL
-C ratio, only feed brown rice group had higher levels of HDL-C and TG concentrations; feed corn starch in liver TC, TG, and TL
concentration
Degree were significantly higher than that, feeding groups and fed polished white rice brown rice group and control group are similar.
Among them, the feeding of liver brown rice
TG concentration was also significantly lower than the group fed polished rice. These results show that: brown rice to increase the role of fecal dry weight maximum.
Ⅰ in experimental diets fed no cholesterol, refined white rice and brown rice can not show significant cholesterol-lowering effect. In real
Ⅰ experience when fed cholesterol diet; or in the fed cholesterol- free diet, then fed cholesterol diets, refined white rice and brown rice
Cholesterol-lowering effects were significantly better than corn starch. In the fed cholesterol diet for 4 weeks, remove the cholesterol diet,
Polished rice and brown rice can make cholesterol levels in rats is reduced to the same control group, and brown rice than white rice.
