The development of hepatitis in Taiwan folk medicine .... the second reported grape
Abstract
(A) the physiological activity of grape Vitis has a diuretic, inflammation, bleeding, wash sore, rheumatic pain, bruises and other roles, civil for the treatment of chronic nephritis, hepatitis, urination pain, trauma, bleeding, wash sore, rheumatic pain. Very chaotic market products and variety, but are Vitaceae (Vitaceae) of the plant, collected in the northern region of this paper is often used in folk medicine of four grape, namely:? Big Mountain Grape:
Ampelopsis brevipendunculata (Maxim.) Trautv. ─ ─ ─ ─ ─ ─ ─ ─ ─ ─ ─ ─ ─ ─
? Guangdong Wild Grape: A. cantoniensis (Hook. & Arn.) Planch. ─ ─ ─ ─ ─
─ ─ ─
? Keelung grape: Vitis kelungensis Moriyama. ─ ─ ─ ─ ─ ─ ─ ─ ─? Lobular grapes: V. thunbergii Sieb. & Zucc. Var. Taiwaniana Lu ─ ─ ─ ─ ─ ─ ─
All kinds of herbs were external morphology and internal structure as compared, for reference for plant identification and assessment of the related physiological activity, including acute toxicity (LD ), liver protection, hemostasis, coagulation, anti-bacterial, anti-
inflammatory, vascular permeability , analgesic, cardiac, anti- mutation effect. Results medicinal roots, Fujibe 50% alcohol
extracts of the most significant effect of physiological activity are as follows:
? Big Mountain Grape (root, rattan): with protecting liver, bleeding, pain, anti-inflammatory, anti-mutation effect.
? Guangdong Wild Grape (root): lowering blood sugar, reduce vascular permeability, anti-mutation effect.
? Toxicity tests in Keelung grape (vine) minimal toxicity, (ip, greater than 16 gm / kg of herbal medicine volume), lobular grape (root) is the most toxic, (ip, 0.83 gnm / kg of herbal medicine volume) . (B) of the Big Mountain hepatoprotective activity of constituents of grape
Vitis Big methanol extracts, after celite column into CHCL , ether, EtOAc, n - BuOH, H O five parts, which showed different degrees of liver protection of existing activity. Active division of the
Department is further use of silicagel and sephadex LH Column
chromatography, were isolated from eight components: β-Sitosterol (I), β-Sitosteryl-glycoside (II), Lupeol (III), (1)
- Catechin (IV), Ampelopside (V), Gallic acid (VI); (VII), (VIII) Kam
Ding. Where (V) is a new glycoside, 3 - methoxy-galloyl-rhamnoside, cause its biological activity, is currently being explored.
English Abstract
