Traditional and non-traditional antipsychotic treatment of schizophrenia, acute inpatient treatment costs compared with the treatment of
A comparative of treatment costs and outcomes between conventional or atypical antipsychotics for schizophrenic acute stage
Abstract
Objective: To compare non-traditional and traditional antipsychotics in the treatment of acute schizophrenia occur during hospitalization cost and efficacy evaluation of treatment in order to understand the actual economic benefit two types of drug treatment.
Methods: A retrospective chart review design, more of a medical center acute schizophrenia inpatients using conventional drugs (haloperidol or sulpiride) (n = 73, mean treatment CPZ equivalent
823.29mg/day) and non-traditional medicines (risperidone or clozapine) (n = 72, mean treatment CPZ equivalent 801.39mg/day) occurred in the treatment of schizophrenia patients and efficacy of treatment costs.
This study the cost of treatment by patients during the treatment of treatment-related costs include: hospital bed fees and
hospitalization fees. Efficacy evaluation from the inpatient unit nurse for the day after admission, the first and second weeks, and the medical records of patients discharged the same day, so as to clinical problems inpatient Rating Scale (MSPI) and functional integrity of assessment ( GAF) to carry out score.
Results: The cost of treatment: Traditional drug group average 129,991.8 yuan, non-traditional antipsychotic group the average 106,582.3 yuan, and the statistically significant difference (p <0.005).
Inpatient clinical problems Rating Scale (MSPI) in the conventional drug therapy group activity and effort, and lack of interest in two points better than the improvement of non-traditional antipsychotics in the treatment group (p <0.05). Rather than the traditional
antipsychotic treatment groups in self-injury, withdrawal, retardation activities, unusual ideas, incoherent, and sleep disorders,
improvement of six points, while superior to traditional antipsychotic treatment group (p <0.05).
Conclusion: The group of non-traditional treatment of clinical problems in patients to improve the project better than traditional group, and control of all variables in the interference, non-traditional groups can reduce the cost of expenditure of 24,836.5 yuan.
English Abstract