Quality control of Chinese herbal medicine research (3) gardenia-Geniposide and Phyllanthus component (2)
Quality Control of Gardenia Fruit-Geniposide and componments of phyllanthus urinaria
Abstract
Gardenia (Zhi-Zi) for the Rubiaceae (Rubiaceae) Plant Hill Huang Zhi (Gardenia jasminoides
Ellis) or the same plant is the dried ripe fruit. With heat, diarrhea, the gallbladder and liver protection such as the role
, Contains a large number of Iridoid glycosides, of which geniposide and its metabolites mainly
To pharmacologically active ingredients. In this study, as a target component, using high performance liquid chromatography (HPLC)
Assessment of commercially available herbs and the quality of processed products; found in the Gardenia (Sui-Zhi-Zi) higher than the mountain Gardenia (
San-Zhi-Zi); hygiene products than processed products; Gardenia Gardenia shell than benevolence. And other Department of mountain Huang Zhi
Points, such as leaves, branches and flower contains only trace even without the other from August to December the new harvest
Fresh Gardenia, the composition changed little. For the 21 kinds of commonly used prescription medicines with Gardenia
, Including eight are scattered, the three yellow plaster Tang, Wu Lin San, Pinggan gas stream to drink, Xiaoyao, wind through
San San, washing powder liver eyesight, tarragon soup, Bupleurum Liver soup, Jingjielianqiao soup Liangge scattered, clear the
Wind soup, soup diaphragm Qingyan Lee, Bai Pi Tang Gardenia, Coptis Decoction, Huanglianshangqing pills, Kidney eyesight
Tang, Yueju pill, Angelica Long Hui Wan, diarrhea and other blue pill and Long Dan Xie Gan. The results show that the other containing Gentiana
3 Prescription: Angelica Long Hui Wan, diarrhea and Long Dan Xie Gan Wan Qing as also with Iridoid
glycoside (gentiopicroside), so analysis of the absorption peaks and geniposide
Overlap, will move through the testing phase to 0.05 M Na2HPO - MeOH (80:20)
[PH = 6.86], it can also quantitatively these two components. In the cast with the same dose, water gardenia
Liver function better than the South Gardenia; Therefore, the choice of medicine should be its content of biologically active components
Basis, rather than the traditional only emphasized the importance of authentic ingredients. Phyllanthus components in addition to the previously obtained
The n-Dotriacontanol mixture, β-Sitosterol mixture and Rutin outside
And then isolated four components Repandusinic acid A fragement, myo-Inositol
, Quercetin and Gallic acid, As for the other components are still in the purification and identification.
English Abstract
