• 沒有找到結果。

十二、處置懷孕患者的特別注意事項

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3. Lu et al. Coronavirus disease (COVID-19) and neonate: What neonatologist need to know. https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25740

4. Zaigham et al. Maternal and perinatal outcomes with COVID-19: a systemic review of 108 pregnancies. https://obgyn.onlinelibrary.wiley.com/doi/10.1111/aogs.13867

5. Chen et al. Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China.

https://www.nejm.org/doi/full/10.1056/NEJMc2009226?query=RP

6. Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–October 3, 2020. https://www.cdc.gov/mmwr/volumes/69/wr/mm6944e3.htm?s_cid=mm6944e3_w 7. Allotey et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of

coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis.

https://www.bmj.com/content/370/bmj.m3320.long

8. Adhikari et al. Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection.

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkope n.2020.29256?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_li nks&utm_term=111920

9. Woodworth et al. Birth and Infant Outcomes Following Laboratory-Confirmed SARS-CoV-2 Infection in Pregnancy — SET-NET, 16 Jurisdictions, March 29–October 14, 2020.

https://www.cdc.gov/mmwr/volumes/69/wr/mm6944e2.htm?s_cid=mm6944e2_w 10. Coronavirus (COVID-19) Infection in Pregnancy.

https://www.rcog.org.uk/media/xsubnsma/2022-03-07-coronavirus-covid-19-infection-in-pregnancy-v15.pdf

11. Torri et al. Disease Severity and Perinatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 (COVID-19).

https://journals.lww.com/greenjournal/Fulltext/2021/04000/Disease_Severity_and_Perinat al_Outcomes_of.3.aspx

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12. Chmielewska et al. Effects of the COVID-19 pandemic on maternal and perinatal outcomes:

a systematic review and meta-analysis.

https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(21)00079-6/fulltext#%20 13. COVID-19 相關說明及確診產婦生產經驗分享.

https://www.taog.org.tw/news_contain_page.php?SN=175

14. 台灣婦產科醫學會 SARS-CoV-2 流行期孕產婦臨床處置暫行指引(第五版)

https://www.taog.org.tw/news_contain_page.php?SN=220

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十三、

處置產婦與新生兒的特別注意事項

✔ 少數確診孕婦其羊水、胎盤、新生兒咽喉拭子與母乳中曾由 PCR 檢出病毒,亦有確診 孕婦之新生兒於出生 24 小時內即為 SARS-CoV-2 PCR 陽性,新生兒可能於子宮內、產程 中,或產後接觸而感染 SARS-CoV-2。

✔ 目前證據顯示,SARS-CoV-2 陽性產婦的新生兒,出生 1–3 天內 SARS-CoV-2 PCR 檢驗陽 性之比率約為 1.6–2%。

!考量新生兒感染風險,建議與產婦充分討論後,將疑似或確診產婦暫時與新生兒隔離,

直至產婦達到解除隔離條件為止。若醫療院所設備許可且產婦同意採行母嬰同室,則須遵 循感染管制原則。

✔ 關於產婦與新生兒處置,建議參閱「台灣婦產科醫學會」、「台灣兒科醫學會」與「台 灣新生兒科醫學會」相關指引。

參考文獻

1. Zeng et al. Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China.

https://jamanetwork.com/journals/jamapediatrics/fullarticle/2763787

2. Interim Considerations for Infection Prevention and Control of Coronavirus Disease 2019

(COVID-19) in Inpatient Obstetric Healthcare Settings.

https://www.cdc.gov/coronavirus/2019-ncov/hcp/inpatient-obstetric-healthcare-guidance.html

3. Detection of SARS-COV-2 in Placental and Fetal Membrane Samples.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205635/

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4. Severe COVID-19 during Pregnancy and Possible Vertical Transmission.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356080/

5. Vertical Transmission of SARS-CoV-2: What is the Optimal Definition? https://www.thieme-connect.com/products/ejournals/pdf/10.1055/s-0040-1712457.pdf

6. Transplacental transmission of SARS-CoV-2 infection.

https://www.nature.com/articles/s41467-020-17436-6 7. Detection of SARS-CoV-2 in human breastmilk.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31181-8/fulltext 8. Evaluation of Rooming-in Practice for Neonates Born to Mothers With Severe Acute

Respiratory Syndrome Coronavirus 2 Infection in Italy.

https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/jamapediatrics.2020.

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9. General Information Regarding Pregnant Individuals and COVID-19.

https://www.acog.org/clinical/clinical-guidance/practice-advisory/articles/2020/03/novel-coronavirus-2019

10. 台灣婦產科醫學會 SARS-CoV-2 流行期孕產婦臨床處置暫行指引(第五版)

https://www.taog.org.tw/news_contain_page.php?SN=220 11. 對於確診/懷疑 COVID-19 母親之新生兒的照護注意事項

https://www.pediatr.org.tw/member/bedside_info.asp?id=29 12. 新生兒 COVID-19 感染臨床處置注意事項

http://www.tsn-neonatology.com/health/content.php?type=&id=19&pageNo=1&continue=Y 13. 台灣新生兒科醫學會 SARS-CoV-2 流行期確診或懷疑 COVID-19 產婦之新生兒照護原則

指引 http://www.tsn-neonatology.com/news/content.php?id=635

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