1. 丁酸會造成 MG-63 類骨瘤細胞的細胞週期的停滯，尤其是在進入 mitosis 期 前，隨 butyrc acid 濃度的上升會更明顯。
2. 在影響 MG-63 類骨瘤細胞由 G2期進入 mitosis 期方面，相關的調控因子包 含 Cdc2、Cdc25C 以及 Cyclin-B1 方面，隨著丁酸濃度上升，抑制了這些因 子的表現，同時也代表著丁酸濃度上升抑制了 G2期進入 mitosis 期。
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有許多可以探討的因子。此外，了解丁酸對於造骨細胞可能的影響之後，如果未 來能夠從抑制丁酸的作用著手，或許可以應用在臨床上治療牙周骨頭破壞或是牙 根尖病變的手段之一。
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圖表
圖 2-1 細胞週期概圖
(Modified from: Cooper GM (2000). "Chapter 14: The Eukaryotic Cell Cycle". The cell: a molecular approach, 2nd ed.)
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圖 2-2 細胞週期之 G
2/M 期概圖
(Modified from : Perry and Kornbluth Cell Division 2007 2:12 )
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圖 2-3 細胞週期中之正向與負向調控因子
(Modified from: http://journals.prous.com/journals/dof/20032809/html/df280881/
images/Kong_f1.gif)
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圖 2-4 活性氧的作用時間、濃度以及對細胞週期的影響
(modified from: Boonstra, 2004)
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圖 5-1-1
圖 5-1-2
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圖 5-1-3
圖 5-1-4
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圖 5-1-5
圖 5-1-6
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圖 5-2 MG-63 細胞(5x10
4)加入刺激五天後細胞存活率的改變 (6
well/ 2mL medium)
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圖 5-3-1
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圖 5-3-2
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圖 5-3-3
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圖 5-3-4
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圖 5-3-5
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圖 5-3-6
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圖 5-3-7
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圖 5-3-8
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圖 5-3-9
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圖 5-3-10
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圖 5-3-11
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圖 5-3-12
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圖 5-3-13
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圖 5-3-14
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圖 5-3-15
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圖 5-3-16
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圖 5-4-1
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圖 5-4-2
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圖 5-5
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圖 5-6-1
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