第五章 結論與未來展望
5.2 未來展望
本研究以電氣紡絲法在不同製作條件下製備小管徑人工血管細胞生長 支架,不但確立了實驗的流程與方法,並針對以高分子材料聚乳酸和聚己
內酯製備出的小管徑人工血管細胞生長支架作了纖維結構、親水性、機械 性質、孔隙率與細胞生長情形等分析,擴大其適合範圍,使小管徑人工血 管細胞生長支架更容易應用於血管組織工程上,但還是有改善與進步的空 間。
以下是未來可研究之方向:
1. 將兩種以上的細胞培養於人工血管細胞生長支架上,組成類似人 體血管的構造。
2. 製作具有方向性的人工微血管細胞生長支架,以便使人工血管細 胞生長支架可適用於更小的尺寸。
3. 製作纖維排列具有方向性且適合培養多層細胞之人工血管細胞 生長支架。
4. 對人工血管細胞生長支架的材料進行改質,使細胞更容易貼附與 生長。
如果可以對上述幾個方向進行研究,相信對於血管組織工程的發展會 有很大的幫助,將來也可以看見組織工程人工血管應用在生醫研究或臨床 上。
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