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附 錄 一
非室性藥物動力學（Noncompartmental model）參數譯名及簡稱：
Tmax：達到最高血中濃度之時間：達峰時間 Cmax：藥物在血中之最高濃度；血峰濃度
AUC0-t：血中濃度對時間之曲線下面積；血藥面積 MRT：藥物之平均滯留時間：平均滯留時間
附 錄 二
石墨爐原子吸收光譜儀測定方法：
(Atomic Absorption Spectrometry，Perkin-Elmer Aanalyst 800 AAS) A.樣品製備：
將血清、血漿、血球或含抗凝劑之血液樣品試管或尿液試管置於 混合震盪器上，使樣品混合均勻。取出 100 μl 樣品置於 1.5 mL微 量離心試管內，並加入 900μL樣品稀釋液[含 0.1 % (m/v) Triton X-100 及 1.25% (m/v) NH4H2PO4 ]，再將此離心管置於混合震盪器上
將血清、血漿、血球或含抗凝劑之血液樣品試管或尿液試管置於 混合震盪器上，使樣品混合均勻。取出 100 μl 樣品置於 1.5 mL微 量離心試管內，並加入 900μL樣品稀釋液[含 0.1 % (m/v) Triton X-100 及 1.25% (m/v) NH4H2PO4 ]，再將此離心管置於混合震盪器上