1995年10月1日創刊 1996年10月1日第一次改版 2000年02月1日第二次改版 2013年02月1日第三次改版
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業 務 單 位 發 行 人 編 輯 委 員 會 主 任 委 員 編 輯 委 員
總 編 輯 副 總 編 輯 執 行 編 輯
潘文炎
(依姓氏筆劃排列) 余騰耀
王釿鋊李 齡馬金玲 鄒 倫楊顯整薄懷照 張兆平
許湘琴
潘惠萍劉惠君羅佳慧
發 行 者 地 址 電 話 傳 真 網 址 設 計
印 刷
登 記 證
財團法人中技社
106台北市敦化南路2段97號8樓 (02)2704-9805~7轉23 (02)2705-5044 http://www.ctci.org.tw 巨門演繹有限公司 信可印刷有限公司 局版北市誌字第372號 中華郵政北台字第5504號
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企劃暨工程科技室 電話 (02)2704-9805~7 傳真 (02)2754-5799 能源暨產業研究中心
環境暨經濟研究中心 電話 (02)2704-9805~7 傳真 (02)2709-8825
電話 (02)2704-9805~7 傳真 (02)2705-9184
2
創藝漫遊
24
百年藥香 世代傳誠
2018
年境外研究生企業參訪活動報導及學員心得分享
人才培育12
中技社
107年技術研發計畫概述
16
淺談科技之星
-CRISPR/Cas9基因編輯技術於 育種或農業應用
20 2018
兩岸循環經濟發展論壇
智庫研究館觀光工廠。
生命體就像超精密的化學工廠，各種物理反應相互影響；對生命體而言，這種複雜的系 統藍圖資訊就存在 DNA 序列中。1869 年 DNA 被陸續解構後，科學家便致力解開此生命密 碼，希望突破先天的限制或修正異常基因。譽為神之手的 CRISPR/Cas9 基因技術是超強大 的 DNA 編輯工具，不但深入了解生命體運作機制，進一步透過基因體編輯達到育種目的；
深信此技術未來的進展速度將越來越快，應用範圍亦越來越大。本社因應政府推動創新產業 之需求，於 2018 年選定「整合數位展示科技應用於工程施工及設計」等 9 項技術研發計畫，
以期開發具產業應用潛力，或即時解決現行工程問題之新技術。
2010 年全球資源開採量 700 億公噸，如維持現今供給模式，2050 年將達 1800 億公噸，
將導致加劇氣候變遷、空氣污染、減少生物多樣性、關鍵資源短缺等風險；因應此危機，「循 環經濟」應運而生。循環經濟是建立在物質不斷循環利用的發展模式，形成「資源、產品、
再生資源」的循環。本社自 2016 年與中國循環經濟協會合作辦理論壇，以廢塑膠、廢紡織、
廢輪胎、城市垃圾資源化、再製造與農業循環經濟 6 大主題進行專題報告，就兩岸循環經濟 發展分享經驗。
新年度的藝文專欄，相繼介紹台北迪化商圈的百年老店，佐以台灣城市速寫畫家的實景
描繪；希望透過遊走捷運巷弄，親身感受大稻埕世代傳「誠」的名店，以及淵遠的文化底蘊。
今年度延續規劃、辦理兩梯次的「境外研究 生企業參訪」活動，秉持著積極扮演境外生與國 內企業之間的交流、媒合平台的精神，持續帶領 於臺灣之大學院校修讀博、碩學位的境外生，實 地參訪國內著名企業，以增進境外生對臺灣企業 之經營實況、企業文化及未來展望有更深入的瞭 解，進而吸引境外生加入臺灣企業工作。企業除 了對參訪的外籍學員們有面對面的溝通及互動、
網羅優秀國際人才的機會之外，同時亦可藉此機 會向來自世界各地、不同國家的學員宣傳推廣企 業價值及品牌，繼續邁向培育外籍人才、企業雙 贏的目標前進。
應廣大同學們的千呼萬喚，有別於歷年來規 劃臺灣北部或中部優質企業參訪行程，特別於 2018 年第一梯次首度策畫參訪南部大型知名企
業，前二天行程安排參訪( 依參訪順序 ) 中國鋼
鐵、光寶科技、河見電機、恒耀工業、統一企業、
宏遠興業等六家盛名遠播且兼具實力的企業，並 很榮幸地邀請到經濟部「投資臺灣事務所」專員，
向境外生簡介在臺灣工作、創業、居留等相關資 訊，後續還可進一步提供就業媒合、襄助創業媒 合，以及協助解決申請簽證、就業金卡等可能遇 到的問題，提供外籍人才一條龍式的國家級客製 化服務。第三天的探索臺灣、參觀具地方文化特 色行程，亦精心挑選到廣受遊客喜愛的嘉義蒜頭 糖廠蔗埕文化園區、板陶窯交趾剪黏工藝園區、
以及彰化鹿港臺灣玻璃館觀光工廠一遊，體驗臺 灣最美的人文及豐富的文化蘊含。
參訪行程第一站，首先到達國內最大鋼鐵公 司—中鋼，繞訪中鋼總公司位於小港臨海工業 區，廠區鄰近港口、機場及捷運，原料進口及成 品出口佔有地利之便。經由企業簡報瞭解到中鋼
粗鋼年產量約1 千萬公噸，製成鋼板、條鋼、線
材等主要產品，產品內外銷佔比約為7：3，加
上在海外建廠的「越南河靜鋼鐵（簡稱越鋼）」
一貫化大型鋼鐵廠投產，除助益於其國際市場的 整體佈局，亦可就地發展中、下游鋼鐵與相關行 業，深化多角化的經營。
榮獲湯森路透《2018 全球科技百強》殊榮
肯定的光寶科技，旗下光電產品、資訊科技、
儲存裝置、手持式機構件等產品皆居全球領先地 位。為開創未來營運成長動能，光寶積極往雲端、
LED 照明、車電、生醫與工業自動化等五大 IoT 應用領域拓展。藉由參訪光寶，學員們得以親眼 觀摩產品製程及相關生產設備，加上工廠廠務代 表詳盡的解說，讓學員們對實際生產運作情形有 突破性的認識。
名列臺灣重要泵浦製造廠—河見電機，參訪 當日，河見電機特別安排其外籍員工進行企業簡 介，分享工作經驗並與學員互動。河見電機在各 式泵浦專業製造上具有著舉足輕重的領導地位，
更從其20 個系列、300 多款應用範圍涵蓋各種
領域的泵浦中，挑選具代表性、特殊性能的泵浦 展示於產品展覽室中，千變萬化的泵浦令人嘆為 觀止。經由導覽人員的詳細解說，全體學員對河 見電機泵浦的流體技術、節能機械發展、以及低 耗能特性感到拜服。
全球前十大螺絲螺帽廠—恒耀工業，核心產 品為「焊接螺帽」，並延伸產製焊接螺帽的冷鍛 成型核心技術，進入汽車用螺帽，朝「汽車金屬 零配件整合製造」方向邁進，成為全方位車用零 組件製造商。工廠內的智能生產設備及各生產線 量產之不同功能、各式各樣的螺絲螺帽皆著實讓 人大開眼界。
榮獲《臺灣20 大國際品牌》殊榮的統一企
業，除致力食品製造，持續拓展新事業，國內外
轉投資相關企業超過200 家，經營項目涵蓋多項
民生消費相關的商品與服務，不僅帶給市場正面
影響也改變人們的生活習慣。Q&A 互動問答與
神祕禮物的加持，炒熱了氣氛也讓學員對統一的 瞭解程度爆表。
以創新和永續聞名國際的智慧紡織廠—宏遠 興業，未受全球景氣不好之影響，關鍵就在於透 過投資來強化產業群聚競爭力。除創立研發中 心、增設機械設備和投入新材料領域外，亦啟動
「放膽射月5+5 全球布局」，規劃海外布點增設
5 國紗布染廠、5 國成衣廠，打造智慧工廠，並
將產業知識（Domain know-how）結合大數據分
析，研發新機能布、找出商機及顧客。
第三天清早，前往蒜頭糖廠造訪超過百年歷 史的古樸木造糖廠火車站，搭乘五分仔小火車出 遊，緩慢行車速度，在車掌兼導覽員的妙語如珠
◤企劃暨工程科技室楊顯整主任˙鍾侑靜管理師
解說沿途田園景致及歡喜高歌中，沉浸在鄉間的 一脈輕鬆悠閒。當然也不容錯過，一定要品嚐糖 廠古早味的暢銷冰品，既清涼又消暑。接著來到 嘉義縣板頭社區，從板陶窯出發，迎著除除微風
騎著4 人共乘協力車遊覽處處充滿藝術氣息的傳
統社區，各家戶牆壁上的壁畫透露屋主之前經營 行業、花漾門牌、小公仔造型郵筒或於各角落尋 獲立體造型逗趣貓咪、小白兔陶偶，感受到在地 人家日常生活，如此親切。社區大型剪黏壁畫以 當地苦楝樹呈現春花、夏葉、秋果、冬枝的四季 景象，如此驚豔。臺灣玻璃館內有令人目不轉睛 的大型玻璃藝術品創作，亦有販售精巧玲瓏各式 玻璃製品，而「黃金隧道」運用玻璃材料、搭配 LED 燈照射、輔以多重鏡面，創造奇幻視覺效 果，彷彿進入新奇的魔幻秘境。第一梯次企業參
訪旅程到此畫下完美句點，以下摘錄27 位學員
參與企業參訪活動的心得感想與眾同享。
The event of 2018 Enterprise Visit for International Graduate Students, which is arranged and sponsored by the CTCI Foundation, is a significant program which has been successfully administered for five straight years. Through visits to Taiwan's prominent enterprises which are representative of Taiwan's industries, CTCI Foundation hopes to act as a bridge, connecting international graduate talents with Taiwan's enterprises in an ever-globalizing world.
Specifically, the main goals of the visits are to foster a deeper understanding about prospect of Taiwan's corporations and working environments, as well as bring together positive interactions between corporations and international participants from diverse backgrounds that are in Master and Ph.D. programs at universities in Taiwan. Through learning about business philosophy, vision, and actual operations of Taiwan's corporations and industrial developments, CTCI Foundations hopes to enhance international students to pursue careers and join corporations in Taiwan, contributing their knowledge and expertise, thus creating a win-win situation for all parties.
Different from previous visits which were located at the northern or middle regions of Taiwan, this year's visits first time targeted prominent corporations in the southern regions of Taiwan. The hosting companies of the first tier of enterprise visit, in order of visiting sequence, include: China Steel Corporation, LITE-ON Technology Corporation, HCP
Pump Manufacturer Co., Ltd., Boltun Corporation, Uni-President Enterprises Corporation, and Everest Textile Co., Ltd.-all of whom are successful and renowned in their respective industries as well as in the world.
It is also an honor to have InvesTaiwan on the visiting list. The governmental agency of InvesTaiwan walks international students through essential topics of staying, living, and working in Taiwan. By providing a simple and single-stop services, its supports range from providing job matching, working visa-related trouble-shooting, to business investment integration.
Activities on the third day include special tours to local sites which represent aspects of Taiwan's natural beauties, local artistic and cultural development. These include Yan-Cheng Cultural Park and Suan Tou Sugar Factory, Bantaoyao, and Taiwan Mirror Glass Enterprise Tourism Factory, all of which receive high praise from tourists and visitors.
As weather at the beginning of enterprise visit was under the influence of typhoon Prapiroon, the first two days of the visiting schedules were accompanies by heavy rains. Despite this, Tier One students showed up on time at the gathering point, and participated with great levels of enthusiasm and curiosity.
China Steel Corporation was founded in 1971, and located in Kaohsiung City, Taiwan.
Situated at the Kaohsiung LinHai Industrial Park, its strategic location is very close to the harbor, airport, and rapid transit system, which makes import of raw materials and export of steel fast and convenient.
It is known that CSC makes annual production of crude steel around 10 million tonnes. CSC produces wide range of products including plates, bars, wire rods, hot and cold rolled coils, electrogalvanized coils, electrical steel coils, hot-dip galvanized coils, and Ti/Ni-based alloy. The domestic market takes approximately 70% of CSC's production and the exports take the remaining 30%.
With its Ha Tinh steel plant already operating in Vietnam, this successfully paves the way for CSC's expansion in Southeast Asia, while integrating middle stream and downstream industries, all the while enhancing its operational synergy.
LITE-ON Technology Corporation is a worldwide leading provider of optoelectronics, information technology, storage devices, and mobile devices components. Their products are used in a broad range of applications, such as computers, communications, consumer electronics, automotive electronics, LED lighting, could computing, industrial automation as well as biotech and healthcare.
According to Thomson Reuters, LITE-ON ranks amongst the “Top 100 Global Technology Leaders”
alongside other international company brands.
During the visit, the up close and personal tours to LITE-ON’ operational plant opened eyes and s mindset of international students, as they were able to observe manufacturing equipment and watch process of product development stage by stage.
Adding to this valuable experience was the detailed explanation by representatives at the plant, which help students to connect academic learning with actual industrial productions.
HCP Pump Manufacturer Co., Ltd. was established in 1979, HCP is the most successful submersible pumps manufacturer in Taiwan.
Since its establishment until present day, pump is constantly the main product, and all HCP staffs are always enthusiastic in developing and implementing better hydrodynamic techniques with lower consumption. Based on the sustainable use and recycle of water resources, HCP continually reforms its products and offers best customer services in an effort to gain highest level of satisfaction from domestic and international customers.
Currently, HCP develops 20 different series and more than 300 models applications for: Waste Water, Municipal & Industrial Water Treatment, Oil & Gas Water Supply, Construction & Mining Dewatering, Agriculture Irrigation, Aquaculture, Landscape, Pumping Station for Flood Control. The output of HCP Pump is about 50,000 units annually, and the volume is increasing continuously.
On the day of the enterprise visit, HCP specially arranged its foreign employee to conduct the company introduction, share work experience and interact with the students. At the exhibition room, the staff explained about diversified pumps which are all made with streamlined technology, energy saving, and low consumption, much to the amazement of student participants.
Boltun Corporation has adhered to the concept of “Quality First, Customer First”. It established a continuous improvement system of
“independent innovation and internal thinking”
and promoted ISO9001, QS9000, and TS16949 from the beginning. The emphasis is not on the acquisition of certificates, but on the implementation of the system and the deep cultivation of ideas to provide customers with stable and high-quality products.The company's products are general purpose fasteners such as welding screws, nuts and other hardware components, which is used for high-grade customized fasteners for the automotive, electronical industries, and industrial machinery with high standards and restrictions.
The tour through BOLTUN's plant provided students with a deeper understanding of the making of different kinds of screws with diversified functions and usages.
Uni-President Enterprises Corporation is dedicated to food manufacturing as well as new business exploration. Being awarded as “2017 Best Taiwan Global Brands”, its business group is consisted of more than 200 companies both within Taiwan and abroad, with business operations covering a wide range of products and services of daily consumption.
After becoming a large business group, the company adopted “social marketing” as their core operating model, to fulfill their obligations as a corporate citizen with the mission of providing a healthy and happy lifestyle. Needless to say, Uni-President has successfully brought about positive influence and impact, as well as changing consumers' way of life and habits. Uni-President is aiming to become one of the largest food companies in the world. Realizing globalization is the crux to overcoming the constraints of an island economy, Uni-President has proactively constructed new plants in emerging markets throughout Asia Pacific, including China, Indonesia, Thailand, Vietnam, and the Philippines to meet the future development and challenges.
Everest Textile Co., Ltd was established in 1988 with its headquarter based in Tainan, Taiwan; it has become one of the few textile manufacturers vertically integrated from yarn, fabric
weaving, knitting, dyeing, printing, and garment manufacturing. Because of this unique advantage, Everest enjoys to have steady growth and profit despite economic recession abroad.
Everest owns five fabric factories, three garment factories, and eight overseas offices around the world. In 2016, the company implemented “Moonshot Thinking 5+5 Global Distribution Plan” to face global competition. From now on, Everest invests strategically for the future:
the company currently has three factories in Asia (Taiwan, China and Thailand), and also plans to build a weaving and dyeing factory in North America and garment factories in Africa. Everest increases vertical integration by establishing garment factories for value-added service, extending weaving and dyeing, and garment factories from Asia to North Carolina and Ethiopia, producing locally for strategic values. Everest also manages to combine domain know-how with big data analysis for continuous research and development of upcoming functional wears. During the visit, participants had the opportunity to see functional sports wears.
On the third day which was a sunny and relaxing day, we headed for Suan Tou Sugar Factory to see its historical train stations with over hundred years of history. All the participants joyfully took the ride on the traditional mini trains, which were used to transport sugars in the past, listening to train guide's explanation and cherishing countryside scenery passing by. Students happily tried the local ice creams and popsicles under the hot weather for a new kind of cooling experience.
Then, at arriving at the Bantaoyao, students rode on quadruplets at the neighborhood filled with artistic elements from decorated mail box, door plates, to pottery in cute animals' forms. The large wall decorations at the neighborhood, shows seasonal changes throughout a year through paintings of bead trees, representative of the spirit of residents at the local region. At the Taiwan Mirror Glass Enterprise Tourism Factory, we encountered a world with fascinating and creative glass art works.
There were many large pieces of artwork, as well as small and delicate souvenirs. Probably the most fascinating amongst them is “Golden Glass Tunnel”, a visually magical fantasy land created by clever uses of glass materials, LED lighting, as well as multi-dimensional mirrors, casting everlasting
memory on the students.
The 2018 Tier One Enterprise Visit ended with high praise from student participants. For now, let us refer to the detailed feedbacks from 27 international graduate students from Tier One.
This activity is very useful and interesting.
As a foreigner, now I am aware that many Taiwanese companies offer job opportunities for foreign students. This activity provides all valuable information about how to apply for work permit and visa for employees. This is very useful for foreigners. Besides that, I also met many new friends from other countries and backgrounds.
We were able to share with each other about our research and other things. At last, I really thank all the CTCI Foundation staff whom really take care of us. Overall, the three-day activity is really satisfactory. I will persuade my friends and my juniors to apply this activity in the near future.
Aindri Yuliane 印尼 (Indonesia)
勤益科技大學NCUT 冷凍空調與能源 碩士
First of all, I would like to thank CTCI Foundation for this very high quality and useful program. Following are some feedbacks which I think are very good to keep for future visits. The program introduced various industries in Taiwan to international students and connected students and enterprises by providing a very good introduction on Taiwan's thriving industries and some companies' productions and services. The selection of enterprises to visit was very well done as they are amongst the industry-leading companies of Taiwan.
It is an excellent decision to include InvesTaiwan Service Center in the program. It is also excellent to include attraction visits with very good sightseeing sites. Aside from that, it is very positive as we were able to make connection with other students of different nationalities from universities in Taiwan.
For me, this visit led to my growing interest to live and work in Taiwan. It also provided me with the opportunity to contact the enterprises and key managers there for future business and career purposes. I have an extraordinary respect to the CTCI Foundation team, for their professionalism, warmth, and friendliness. Emails were very well Ali Montazami 伊朗 (Iran)
淡江大學TKU 未來學研究 碩士
I knew from before that Taiwan has advanced technology, from the visit, not only did I get to see very high technological development, but I also saw wonderful art performance. We visited China Steel Corp., Uni-President Enterprises Corp. and other international manufacturers in Taiwan, I have to say thanks to all of the hosting corporations as they were very kind and helpful to everyone.
In the last day, we travelled together through old sugar train station of Suan Tou Sugar Factory, Glass Museum and Bantaoyao. All of us had a lot of fun and enjoyed much from the trip. During the visits, I saw some foreigners who are working in Taiwanese factories and they have inspired me even though they did not speak Mandarin well- they were all trying to do their best. Personally, working abroad is a very unique experience for me in life. CTCI Foundation staffs organized this wonderful visit, and moreover, they tried to help us to explore job opportunities, as well as assistant us to stay on this beautiful island. In addition, I met new friends from different countries, learning about each other’s culture and helping each other out during the trip. A friend from Indonesia in particular has perspective that was completely different from mine. We exchanged ideas and thoughts about studies and many things. We are still keeping in touch, and now I have very good friends who are studying in other universities and in other cities of Taiwan. The CTCI staffs were helpful to everyone, talking and treating students with kindness. What I learned is that, kindness is Generally speaking, I have been very
satisfied with the trip of enterprise visits. Through it, I realize and learn about how each company started from scratch, built management system, Bui Thi Hiep 越南 (Vietnam)
成功大學NCKU 資訊工程 碩士
Dashnyam Chuluunkhuu 蒙古 (Mongolia) 勤益科技大學NCUT 空調冷凍與能源 碩士
Darge Haile Fentahun 衣索比亞 (Ethiopia) 臺灣科技大學NTUST 應用科技 博士
The 2018 Enterprise Visit activity had been very enjoyable. I really want to give thanks to the CTCI Foundation, accompanying staffs, InvesTaiwan, all enterprises and fellow participants. I thoroughly enjoyed the three-day trip, and believe it is one of the best activities for international students who want to work in Taiwan after graduation. The best thing about this activity is that, it helps me to understand the current developing trends of enterprises and technologies which are applied in industries today. From there, I can build a suitable roadmap to fulfill my ambition to apply computer science and information engineering in the industry, as well as contribute to the development of society in general. Through visits to the enterprises, I realize that besides having good professional skills, Chinese proficiency is one of the most important requirements for finding a good job in Taiwan. This is a message which I will inform my international friends.
And it would be a great omission if I forgot to mention our sightseeing on the third day of the activity. We visited various famous and interesting places in Chiayi and Changhua, places where we were immersed in beautiful nature and interesting stories of the country. I benefited tremendously from the 2018 Enterprise Visit. I will definitely introduce it to my friends, so that the benefits and meaning of the activity will be widely shared with everyone.
Once again, I would like to send my deepest thanks to the CTCI Foundation, and especially accompanying staffs who worked really hard to give us a really great activity. I appreciate greatly and I am grateful for the assistance and support.
designed to give enough information to participants to make us ready before the trip. CTCI staff especially had very good attention to details and didn’t miss students’needs.
took measures to deal with environmental pollution, and committed to the training and development of people, as well as quality of their products and innovations, so as to be competitive in the global market. I personally believe that this activity makes interesting impressions on students and helps us when considering about future career directions. As a student, it inspires me and shifts my future career direction to participate and contribute my best ability in different companies for better development. I am greatly appreciating CTCI Foundation for their initiations and grants for us to visit enterprises, and I recommend CTCI to continue this fantastic activity. Thank you so much!
I would like to thank CTCI Foundation for sponsoring all international participants for the interesting Enterprise Visit. I got a good chance to visit the top industrial companies in Taiwan. I can see and learn about how the companies are organized and running business logically.
I want to thank the CTCI Foundation for organizing this interesting trip for international graduate students. I also really appreciated the hospitality of each company and this is a good sign of working environment which is extremely important to foreigners.The impact of such activity is obvious and visible: it is a great opportunity for us by connecting with successful companies and entrepreneurs, so we can learn from their experiences. These companies successfully integrate their working staffs as a team to achieve profit goals and earn money. The visit also inspires us as graduate students: I consider this as a good step for my future career, to bring back these experiences to our respective countries, and help contribute to our economic developments as well as environmental concerns. As the participating students are from different universities and specialize in various fields of study, this gathering helps us to build up new friendships which all of us can continue to profit in the future in many ways.
Big thanks to the organizing and accompanying staffs who arranged the visit to each company and also the driver. I hope that CTCI keeps doing this kind of trip so that other new graduate students can enjoy exploring more things about Taiwan.
Emmanuel Leonard 海地 (Haiti) 中央大學NCU 遙測科技 碩士 DO TRONG NHAN 越南 (Vietnam) 成功大學NCKU 土木工程 博士
The 2018 Enterprise Visit held by the CTCI Foundation gave me a chance to learn a lot of new knowledge about enterprises and their factory operation in Taiwan. All the companies we visited are good and appropriate in the Industry 4.0 era.
Few industries are categorized as steady industries such as China Steel Corporation and Boltun Corporation. CSC, which produces steel, improves its product quality by learning from different kinds of industries; while Boltun, which produces fasteners, adapts methods such as enlarging the range of industry to P2C by opening the Pineapple cake bakery store. I personally think CSC and Boltun have very good business models. In addition, these companies provided useful information about strategies on their industrial expansions in the future.
Useful and emerging technologies were introduced, which opened new perspectives for these industries in the future. The trip also included sightseeing. The attractions we visited were interesting, especially the Taiwan Glass Factory. Through this Enterprise Visit event aims for international graduate students, all of us are able to understand how Taiwan conquers various industries globally. We learn a lot of new knowledge and company strategies on how to run business. Most important, this activity is an eye opening experience that could expand our job opportunities in Taiwan.
Gilang Baswara Anggara Putra 印尼(Indonesia) 中央大學NCU 應用材料科學 碩士
This is the first semester in my graduate study and the first time I visit industrial companies here in Taiwan. It is such a great experience The enterprise visit was perfect from the beginning until the end. Especially, it was great we were able to visit the Boltun Corporation and saw its actual processing operation. The coordinators gave detailed information throughout the visiting program. And the schedule and time management were efficient. I would like to say“keep up the good work”, and thank CTCI Foundation so much.
Iffandya Popy Wulandari 印尼 (Indonesia) 中央大學NCU 機械工程 碩士
BALKEW ZEWGE HAILEMESKEL 衣索比亞(Ethiopia)
臺灣科技大學NTUST 應用科技 博士 not only helping people on daily aspects, but also
treating them with kindness. The students were from different countries, but we were all treated as the same without difference. This enterprise visit was very wonderful and there were a lot of enjoyment and new experiences in my life. We had been together only for three days, but I felt these days were very interesting and enjoyed a lot. Thank you CTCI Foundation!
I learned so many things about Taiwan’s company culture, working environments, and job opportunities. Moreover, the presentation by InvesTaiwan Service Center gave us clear ideas about job and work permit which is the first step for any job seeking student. Most of the visited companies were somehow linked to my research as I came to learn about their job requirements.
And I could consider if I want to seek jobs with these companies in the future. The most important thing about this trip is that there are candidates from different countries, cultures, universities and backgrounds, which helped me a lot when learning about different fields of studies and related trends.
The CTCI staffs guided us during each company visit in such way that I don't have the words to express my feelings and gratitude towards them.
Everything from the enterprise visit was perfect, and I have to say it is the best visit I have ever had during so many years living in Taiwan.
We really enjoyed the enterprises' presentations.
During the companies' presentations, the participants had the opportunity to ask questions and visit the operation sites. This allowed positive, active, and direct exchanges of experiences between visitors and host companies. However, in terms of job opportunities, I realize that Chinese language proficiency is also part of the company's necessary requirements to hire employees for their business. On the side, the accommodation in every city was very good-all the hotels were upscale and I had very good sleep as the rooms were very comfortable. Moreover, the foods were so delicious. And the driver was very good with his driving and drove very safely. The bus was also very clean and comfortable. It is really high-class visit. In summary, the whole trip was extremely well-organized and offered so much more than we expected with all the interesting side trips on the third day, sightseeing, and a lot of surprises. Thanks to CTCI Foundation because the enterprise visit went well and we were very satisfied. Thank you very much for having arranged the magnificent trip we took!!
CTCI Foundation worked really hard with accuracy in finding and matching the most representative companies and participants that fulfill each other's needs during the enterprise visit.
The enterprise visit was carefully planned-even the most minimal detail was taken into consideration.
The enterprise visit is one of the best opportunities for foreign students to get to know more about different Taiwanese companies, recruitment procedures, and related requirements, as it is hard for some of us to get enrolled into Taiwanese companies. It's been a great experience and opportunity for me. My desires to grow personally and professionally increased from the trip. Thanks so much to CTCI Foundation for the quality job done this year.
I would like to thank the CTCI for give me the opportunity to be part of this knowledgeable program. I gain so many insights about the visited Taiwanese companies listed below: China Steel Corporation produces a range of steel products including plates, bars, wire rods, hot and cold rolled coils, electrical steel coils, hot-dip galvanized coils and Ti/Ni-base alloy. In its production, the corporate value of teamwork, entrepreneurial Maaz Ajvad 印度 (India)
長庚大學CGU 機械工程 碩士
Martin Flemming Panggabean 印尼 (Indonesia) 中興大學NCHU 科技管理 博士
Mohamad Nor Hisyam Bin Mion 馬來西亞(Malaysia)
勤益科技大學NCUT 冷凍空調及能源 碩士 for my studies. Thanks to InvesTaiwan Service
Center, I got a lot of information about working in Taiwan, which sure can let me pursue my career in the future. This is especially a good program for international students, and I also met new friends from other countries. Finally, I hope this event will exist year after year.
LOBO PACHECO ISAMARA ALEJANDRA 哥倫比亞(Colombia)
南臺科技大學STUST 機械工程 碩士
The trip and its planning were wonderful, and hospitality from CTCI Foundation was awesome.
Thanks to CTCI Foundation for organizing such a wonderful trip.
The trip of enterprise visit was very informative, and it helped me to make connections with my own academic domain. Besides the focused learning, we also enjoyed a lot from the trip. I respect the CTCI Foundation as it continuously provides all the necessary requirements according to the norms and interests of the students from diverse backgrounds and different countries. I consider myself to be very lucky to get a chance to visit Taiwan leading companies, which I don't think it would be possible for me to visit by myself. Thanks to the CTCI Foundation for providing this wonderful trip and experience. Overall, the enterprise visit was good and one of the most resourceful and best trips I had in Taiwan. The work CTCI Foundation is doing is really unique. Thanks for everything.
Thank you so much for cordially selected and invited me in the enterprise visit tour. I appreciate all your efforts during the tour as well as I was highly impressed by pre-planning of three-day tour arrangements. I really enjoyed meetings with all famed enterprises. Finally, my high gratitude goes to entire CTCI team and all my international friends. I wish our contact with each other will last forever.
First of all, I would like to give my thanks to the CTCI Foundation for organizing this high quality trip and guiding us throughout the three days. I knew that Taiwan has many big enterprises, but it was through internet or television, this Gaurav Pandey 印度 ( India)
長庚大學CGU 機械工程 碩士
Ramteke Nikita Anil 印度 (India)
高雄海洋科技大學NKMU 航運管理 博士
PHAN DINH VAN 越南 (Vietnam) 元智大學YZU 資訊管理 博士
approach, pursuit of innovation is easily to be seen. The CSC group, which including its 26 subsidiaries, deems environmental protection and energy saving and centers its development in Asia. It is making efforts to become a resource- saving and eco-friendly group of global distinction.
LITE-ON products are used in a board range of applications, such as computers, communications, consumer electronics, automotive electronics, LED lighting, cloud computing, industrial automation as well as biotech and healthcare. And it has been shifting its production focus from IT and communication towards IoT applications such as cloud computing, LED lighting, automotive, biotech, and industrial automation. HCP Pump Manufacturer is the most successful submersible pumps manufacturer in Taiwan, and has developed 20 different series and more than 300 models, each with its unique usage.
opportunity allowed me to visit these companies directly for the first time. I also would like to thank all of the visited companies for their warm welcome and introductions. Although my current research is not very relative to the visited companies, this trip has affected my view for the future. When I finish Ph.D. program here, I hope that I will have an opportunity to cooperate with a company or research center in Taiwan. I hope I can also learn many things in the professional working environment of these companies. As a lecturer, I have gained much experience for my part, and I will share many stories from this trip with my students. It was a great trip.
Thank you for arranging this great event.
Through this enterprise visit, I gain more insights to the industries in Taiwan. Hopefully, this event can act as bridge between international graduate students who wants to pursue their dream career to Taiwanese organizations.
I enjoyed the Enterprise Visit and treasured the opportunity very much. The hospitality and dedication from the CTCI Foundation team were extraordinary, and these made me think the Taiwanese society is special. The visited companies are all great and doing remarkable business globally. We had a great learning experience while visiting these world-class renowned companies, having real-time glimpses of their manufacturing Resza Diwansyah Putra 印尼 (Indonesia)
東海大學THU 化學工程與材料工程 碩士
Sudhir Pandey 印度 (India) 中國醫藥大學CMU 生物醫學 博士
This visit is really fruitful to international students because it creates a good platform for international graduate students to understand the industrial requirements for work and employment in Taiwan. The visit covers different kinds of industries, this is actually a good idea as it is beneficial for students to meet their dream industry based on their educational and research interests.
The visit also offers a chance to learn new and interesting things which are outside students' research circles. My feedback for the visited corporations and the visit is listed below:
(1) The presentation by InvesTaiwan Service Center speakers helped us to know more information about the procedure of applying for a work permit.It also helped us to know more about the types of VISA, respective advantages and requirements.
(2) The policy of green working environment by the Everest Textiles seems to be very attractive and unique. The strategies of“moonshot thinking 5+5 global distribution plan”and
practice of AI during their manufacturing process The CTCI Enterprise Visit is one of the Veeramani Rajendran 印度 (India)
臺北科技大學NTUT 製造科技 碩士
VIPUL DUBEY 印度 (India)
臺北科技大學NTUT 自動化科技 碩士
demonstrate their future forecasting capability.
(3) Uni-President Enterprises is one of the unforgettable enterprises from the visit. I was so excited when I heard it is the manufacturer of daily products sold at 7-11 convenience stores. I appreciate the company’s statement that the addition of new things is always required for business to turn successful.
(4) The visit to Boltun Corporation created ever- lasting memory because of their name which is made up of “Bolt” and “Nut”. They displayed all kinds of bolt and nut and discussed a lot of technical information of manufacturing during the plant visit.
(5) The presentation of HCP Pump Manufacturer discussed about the importance of water and pump as well as changed the idea of the pump in general people's mind. I am excited to see that different research opportunities are available in pump manufacturing.
(6) LITE-ON Technology is one of the enterprises which I am personally glad to visit because my research is more related to the optoelectronic industry and it is my first time to visit a semiconductor fabrication plant site. I appreciate LITE-ON greatly because a lot of semiconductor industries would not allow guests to actually see their product processes.
(7) Since I got a chance to visit two leading public sector steel manufacturing industries while I was pursuing my bachelor studies, therefore, I could understand how hard it is to visit a grand steel factory site in one hour. CSC tried to show all the processes by sitting on a bus which was truly appreciated. That’s the first time that I knew Taiwan has an integrated steel plant to produce in high quality and large quantities of steels compares to China.
(8) The sightseeing on the last day of the trip was really mind-blowing and I look forward to having such day again in my life. The photos taken in Taiwan Mirror Glass Gallery are stunning and I have received a lot of likes and comments from friends on the social network.
For the 2018 enterprise visit, the companies we visited in the trip are big and famous, and very well represent each specific industry. Through the company introductions and plant tours, we learned a lot about each corporation. As well, we also got to know some job opportunities. It was definitely a good starting point for us to look for a job in Taiwan. Furthermore, meals, transportation, and accommodation were all good. Thanks very much to CTCI Foundation for organizing such a meaningful event for international graduate students.
Phan Dinh Minh Tri 越南 (Vietnam)
高雄第一科技大學NKFUST 國際管理 碩士 and production processes. Visiting Uni-President Corporation was of special interest to me personally.
Since I am studying in the field of Biomedical Science, therefore, it would be great if few healthcare or biotech companies could be included for future enterprise visits. I will look forward to hearing future information and update from CTCI.
Thank you for the support for foreign students.
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CTCI QUARTERLY 127
I enjoyed the Enterprise Visit event held by the CTCI Foundation and felt really satisfied.
Aside from the great experiences of learning details of each company and its respective industry, I also made new friends. One of the advantages by participating in this event is that, I have an opportunity to forward my resume and CV to companies that we have visited. By viewing insights into the visited companies and real working fields, that help me better manage and prepare for the job requirements. CTCI staffs treated us very nicely and all schedules were arranged very well. Thanks to CTCI Foundation for the great experience!
Actually, the 2018 Enterprise Visit exceeded my expectation. The enterprise visit was a great opportunity for me to learn more insights about Taiwanese enterprises. Now I am considering getting a job here in Taiwan. As a foreigner, I could be a bridge between Taiwan and another part of the world. Thanks for all the information you have provided. Overall, CTCI Foundation did a great job to satisfy everyone. I was very happy to take part in this visit, and I would like to thank CTCI Foundation for this initiative. Keep up the good work! For sure, I will talk to many people about CTCI Foundation and the enterprise visit activities.
The 2018 Enterprise Visit was well scheduled and conducted. A suggestion to make this useful activity even better is that, for each tier of the trips, CTCI Foundation could match the fields of interest and major of studies of participants with selected enterprises to be visited. That could help participants to enjoy their visits and have the opportunity to meet their potential future employers at the same time.
William 印尼 (Indonesia)
臺灣科技大學NTUST 材料科學與工程 碩士
ZOGONA DANIEL 布吉納法索 (Burkina Faso) 中國醫藥大學CMU 營養學系 碩士
Zikril Hakim Bin Salam 馬來西亞 (Malaysia) 勤益科技大學NCUT 冷凍空調與能源 碩士
ZONGO Abel Wend-Soo 布吉納法索(Burkina Faso)
中國醫藥大學CMU 營養學系 碩士
Zikril Hakim Bin Salam 馬來西亞 (Malaysia) best group trips I have ever had in Taiwan. The enterprise visit was quite a learning experience about the working culture in Taiwan. I was able to meet many other students and develop some good contacts with these friends from different countries and working backgrounds.Being part of this program also opens the door to possible opportunities to work in Taiwan. During this enterprise visit, I came to realize the importance of Chinese communication skills for finding a job in Taiwan. Overall, this enterprise visit allowed me to link up with people of similar interests, to constitute a comprehensive learning experience that would be helpful for my career ahead. To sum up, I would like to really thank the organizing committee and praise them for all the efforts they put into making this trip a great experience for all of us. I believe that CTCI Foundation tried their best. I am highly impressed by the overall trip and would love to recommend my friends for future enterprise trips.
Everything was perfect about the visits and its arrangement, and the visiting companies made us feel welcome. The overall experience was gratifying- it was an awesome opportunity to meet friends and learn about different enterprises in Taiwan, this would not have been possible by myself.
ALELY RAMOS VELASCO 薩爾瓦多(El Salvador)
中央大學NCU 國際永續發展 碩士
This is my first time to join enterprise visit with participants from many other countries. Personally, I think the enterprise visit was good. Throughout this trip, I visited various representative companies and learned about their productions and products.
It is great to know many Taiwanese companies hire foreign employees. This activity also makes me realize that Taiwan has many good companies that we can work for or do business with in the future. Through it, I have built good connection with other international students as well as with CTCI Foundation staffs. All the CTCI staffs are great people whom made this enterprise visit to be such a great one. You made our job easy and thank you for that. You did such a great job and you are awesome!
因應政府推動創新產業之需求，本社極 力開發具產業應用潛力、可即時應用及解決 現行工程問題之新技術， 107 年共選定 9 項 技術研發計畫，重點概述如下。
國內工程公司積極參與國內外輕軌及 捷運軌道等基礎建設工程，為改善舒適度與 軌道維護的方便性並解決橋上長軌合宜之設 計，進行軌道工程技術以提升軌道工程之整 體競爭力。長焊鋼軌為現代化軌道工程技術 的趨勢，但不同軌道系統通過不同型式橋梁 所產生之複雜力學問題，攸關軌道系統挫曲 / 拉斷之安全及衝擊生活品質的振動噪音，已 成為軌道設計的關鍵技術之一。
由於伸縮接頭、橋軌互制兩項課題須 考量列車輪軸配置形式，橋梁跨距、枕木間 距等因素，亦需要實測數據綜合研判車速與 橋梁共振問題。本計畫將由行車安全角度 切入，透過文獻回顧歸納高架橋上無碴軌 道受橋軌互制力影響行為、軌道設計關鍵因 素及相關規範，了解軌道鋪設於橋梁所產生 之複雜力學問題。從靜力分析角度探討橋軌 互制力之特性，評估是否需設置伸縮接頭來 降低橋軌互制的影響。另參照國際鐵道聯盟 規 範 UIC 774-3R “Track/bridge Interaction Recommendations for calculations”， 探 討 研究範圍與變因後，歸納相關文獻與理論。
並根據規範建立橋軌互制有限元素分析模 型，以及遵照條件及參數規定完成分析模型 之基本驗證，確認分析結果符合國際規範，
掌握橋軌互制理論、分析工具、設計能力。
軌橋互制行為及鋼軌伸縮接頭設置研究
轉動設備聲學監測之低耗能雛型產品開發 工業 4.0 其中一項是結合工業物聯網與 大數據分析，應用在不同領域的製造場所，
透過即時訊息蒐集，達成預防故障、降低成 本、提高產能等目標。目前市場上最普遍使 用的轉機設備預兆診斷系統是以量測振動變 化的方式進行，如要達到精密量測的目的必 須安裝昂貴的振動分析監視系統 (VAMS)，
並在設計階段就必須進行規劃，無法安裝於 既有設備上，且在現場需要配置電源與訊號 傳輸線路，其建置成本昂貴，因此通常僅安 裝在大型重要設備上，無法對於所有的設備 進行監測，使得工廠存在不預期停車的風 險。
目前在工廠中重要的轉動設備如馬達、
減速機、壓縮機、引風機等，其內軸承等易 磨損或故障之元件通常定期以聽診器檢查，
或裝設振動、溫度量測之監測，作為分析設 備劣化或損壞情形之依據。本計畫使用小型 收音裝置收錄轉動設備所發出的噪聲，再應 用大數據演算及機器學習等技術，取代人工 聽診的方式來達到預知保養的目的。前期計 畫已使用樹莓派 (Raspberry Pi) 加裝麥克風 及音效卡做為現場收錄音裝置，再搭配開發 的分析監視系統達到預警目標。唯樹莓派仍 為較耗電之裝置，必須以外部電源持續供電 才能維持長時間運作，實務上不符合易於安 裝與使用的需求。因此與中正大學通訊工程 學系研究團隊合作研發，以電池供電能運作 一個月以上，並在工廠環境中傳輸成功率達 90% 以上的低耗能小型無線錄音模組雛型 產品；並以設備噪聲分析為基礎的低成本預
◤企劃暨工程科技室楊顯整主任 ‧ 劉惠君副管理師
化工 4.0 虛實整合系統示範工廠建置 兆診斷系統，結合前期成果開發可業務推展 之低耗能轉動設備聲學監測產品，提供設備 預兆診斷系統之解決方案，減少錯誤警報之 機率。
國內半導體製造業堪稱我國電子產業 龍頭，其中晶圓製造業、封裝業及導線架產 業和光電業中的 LCD 及 LED 製造業所使用 之化學物質及有機溶劑最多。依據環保署事 業廢棄物管制中心資料顯示，國內廢溶劑之 年產量約為 15 萬噸，其中屬一般性廢溶劑 為 88,313 噸 / 年，屬於有害性廢溶劑則為 65,324 噸 / 年。目前半導體及光電產業的主 要污染物可分為毒性及有機廢氣、廢溶劑及 廢水。國內廢液處理之方式有：委託或共同 清除、廠內自行處理、再利用、境外處理。
民國九十年四月二日政府公布「水泥窯」可 作為有機廢溶劑處理的技術之一，營業項目 包含易燃性廢溶劑、廢潤滑油、廢污泥、去 光阻液、蝕刻廢液及其他有機及無機廢液 等，但是目前水泥窯處理方式有其缺點（磚 窯品質低、排氣中含污染物廢氣），多家廠 商不願意再承接處理，含水量高的廢液不易 處理，導致處理費用升高。本計畫以廢異丙 醇為出發點，分別以反應蒸餾系統加上滲透 蒸發技術及化學迴路燃燒之製程進行處理。
其中，反應蒸餾系統加上滲透蒸發技術可將 廢異丙醇轉換且純化為高單價溶劑用於油 墨、塗料溶劑、脫水劑等，而化學迴路燃燒 可以產生極高純度的二氧化碳，進一步的做 資源化建材或是將其二氧化碳封存。
在虛實整合系統中，其核心為透過收 集下來實部的數據，將實體模型數位化成數 位 雙 生（ Digital Twin）存在於虛（Cyber）
的環境中。在虛部空間裡，由於數據擁有 流動性（數據無國界無時差），所有的運算 與資訊交換都可透過網路快速進行，因此可 讓 Digital Twin 在任何地點或裝置上即時呈
現最新狀態，忠實的紀錄與反應實部空間
（ Physical Space）的一切。而數位雙生最 大的功用在於透過模擬優化，對實部模型進 行指導與修正。然而若收集不到數據，就無 法建構出數位雙生，也無法創造虛實之間的 整合。因此，本項技術開發第一步要將 Pilot Plant 中各種設備與製程狀態相關參數收集 下來，接著再建構出設備（如蒸餾塔、流體 化床）之數位雙生。
虛 實 整 合 系 統 為 工 業 4.0 關鍵技術，
藉由蒐集實部空間（ Physical Space）感測 器的訊息，透過新一代整合技術在虛部空 間（ Cyber Space） 建 立 數 位 雙 生（Digital Twin），且數位雙生能完整呈現系統的行為 及特性，對實體空間的設備達到監測、分析 及最適化的功能。因此，配合台科大異丙醇 廢水處理研究，對反應蒸餾及化學迴路燃燒 系統 Pilot Plant 進行虛實整合系統的建立。
在現今環保意識抬頭、寸土寸金的台 灣，煉油石化工廠任何一個閃失發生毒性氣 體洩漏，或管線腐蝕而破裂，都可能導致嚴 重工安或環保事件，不但影響整座石化廠的 運作，相關人員還可能需負刑事責任。如果 建構一套完善的 P&ID 資料庫：在操作面，
能夠提供正確且豐富的製程與設備資訊；在 設計面，能有精確的規則檢查、一致的參考 標準與彈性的屬性建立；在管理面，數據源 自於唯一資料庫，讓版本管理更簡化，智慧 保存更方便；在應用面，能透過建構製程安 全相關資訊，突顯工廠關切的工安議題。整 體而言，對於提升工廠的操作安全、維修品 質，降低工安或環保事件的發生風險，都會 有很大幫助。
面臨前述問題，導入智能化 P&ID 軟體
( 例：SmartPlant P&ID 簡稱 SPPID ) 刻不容
緩，它的最大核心價值，簡單來說是採用資
料庫的方式並規範出統一標準與規則，解決
工廠 P&ID 製程安全管理應用
為提升行李裝載從業人員工作效率及延 長機場從業人員之工作壽命，降低高齡工作 人員的職災等問題，行李裝載作業的自動化 和半自動化未來將成為必然之趨勢，目前極 力開發設計出符合行李裝載從業人員省時又 省力之相關智慧省力裝置。
目標為簡化搬運流程 1/2，目前搬運行 李流程為檢視裝載航班 -> 提行李 -> 手持機 確認行李 -> 搬行李入櫃車，改善後搬運行李 流程為檢核行李 -> 搬行李入櫃車；並使用省 力智慧裝置，約可減輕搬運人員 2/3 施力。
目前搬運行李人員每件行李所須勞力約 20 公斤，一個航班最多行李數為 600 件，以此 類推每位搬行李人員須要在一定的時間內處 理完成 12,000 公斤行李量；若由省力智慧裝 置代勞，人員的施力將由 20 公斤降至 7.6 公 斤，約可節省現有搬運人員約 2/3 的勞力。
裝載行李若還需用手輸入相關資料，對搬運 者非常不便，目前最有效方案是利用航空公 司提供行李條碼及螢幕產生之新二維條碼，
再用掃描機進行輸入。本計畫致力開發無限 手套穿戴省力裝置產品，預期可提升行李搬 運人員的工作效能，及增強物聯網相關技術 整合及深度運用。
過去傳統製造業的品管作業產品檢測過 程皆人為操作，冗長的作業模式容易使操作 者出現人為偏差、疲勞、注意力分散等問題。
且使用人工進行產品檢測，只能採定時或批 次抽驗，無法百分之百的全檢；若以智慧光 學量測系統將人工檢驗作業全面自動化，將 可減少現場及品管人力需求、縮短檢驗時間，
即時掌握產品品質狀況，更能提高檢測速度 而加快產品製造流程，提升出廠產品的品質 水準，進而減少廢品的產生機率。
智慧光學量測系統的原理，主要是透過 光學裝置和非接觸傳感器，自動獲取目標影 像，再由影像處理設備根據所得影像的畫素 分布、亮度和顏色等訊息，加以運算處理及 判別分析，能在短時間內獲得所需的特徵訊 息，或根據判別分析的結果，對現場設備進 行運動控制；透過智慧光學量測系統的導入，
物體的外觀資訊大量的被累積下來。不論是 外形、尺寸、高低、顏色等都能夠快速地被 記錄分析，產生可以做為控制判斷的資訊基 礎。更進一步將這些累積下來的資料進行分 析，加工的流程及作法都可依照資料所提供 的訊息作為基礎得以改善優化。
為開發能用於傳統製造業生產加工製程 的智慧光學量測系統，與工研院光電所光學 合作，開發專業與影像處理 / 影像辨識技術，
包括光學量測設備機設計、開發、組裝、調 教 ( 含影像處理、物件量測軟體設計 )，量測 數據的傳輸、收集、儲存及大量量測數據之 智慧光學量測系統 (iSharp) 開發計畫
機動型行李裝載省力智慧裝置計畫 統計分析。本計畫成果可應用於塑膠加工產 業之 PVC 塑膠硬管管徑及壁厚的自動量測，
以達提升檢測速度、加快產品製造流程，並 能提升出廠產品的品質水準，包含：自動即 時取得被測物件之量測數據、量測數據可以 做為生產控制判斷的依據，改善產品品質。
量測數據不會因人而異，可信度提高、降低 品管人員及現場人員人力需求、掌握光學設 備機設計及光學設備調教技術、了解智慧光 學量測系統的適用場域及限制，並建置完成 智慧光學量測雛型系統。
管理及應用上的不便與缺失，透過它可快速 進行整個工廠設備資料的統計分析、查詢、
更新，甚至可以做到變更資料而自動驅動某
些圖形的相對應變更、自動計算、產生不一
致性檢查報表等功能。另外，可再透過各種
外接程式語言，實踐客製化功能，協助進行
相關自動化作業。
工程的生命週期分為原料開採、材料生 產、材料運輸、施工、維護、廢棄等六階段，
與營造相關的是材料運輸、施工兩階段。彙 整材料運輸以及施工機具的油料耗用乘上碳 排放係數，再加上施工階段所使用之水電能 源耗用，即為施工階段碳排放量，從製造端 介入計算，以建立更準確的前端盤查結果。
本計畫以常見之道路工程 ( 園區開發、
市區道路與市區橋樑 ) 為例，分析工程設計 之道路工程碳足跡，建立碳排放量基線。另 結合開發的生命週期評估軟體，搭配設計及 施工成本，進而制定減少碳排的綠道路設計 綱要，使用碳排量少之材料，增進機具使用
順應科技潮流與市場需求，工程單位 積極投入多媒體技術，培養未來實現 VR、
AR、MR 等互動式應用技術的實力，藉由高 品質的展示內容，研究工程應用面數位科技 化，除可強化公共工程及智能建築設施等設 計，更能為社會大眾提供多元創新的服務。
為反應市場需求，本計畫將投入優化動 畫製程與展示體驗相關研究與人才培育。目 標是將虛擬實境（ VR）的內容以「環景投影」
展示，於製作產出內容的過程中，以既有的 BIM 系統與 3D 動畫經驗為基礎，並以「和 技術相契合的內容生產力」為發展核心，配 合三大策略方向：精準化（活用數據 / 企劃 方向正確）、優化（內容與視覺精緻化）、
程序化（提升創造內容的效率），與相關數 位展示領域（虛擬實境的環景投影）之軟硬 體技術研究。透過精進「展現的數位內容」
使團隊的動畫技術愈來愈擬真。開發成功後 有利於人員即時檢視建築、管架、機電、空 調等設計成果，可降低施工風險與提升服務 品質，並藉由視覺化的完工展現，提升與業 主間的溝通。
機器人智能銲接系統開發
建立綠道路設計綱要及生命週期評估軟體
整合數位展示科技應用於工程施工及設計 效率，最後執行道路的能耗碳排基線。利用 全生命週期的碳足跡計算結果，建立工程專 案的綠色施工基線 (baseline)，提出綠色設計 與施工策略，如採購綠色材料、短距離運送、
有效率使用施工機具、減少廢棄物等。
藉由建立碳排放量減少策略，在綠道路 工程上取得前端、永續專業之優勢，進一步 完善材料與機具碳排係數資料庫，導入生命 週期評估概念。發展綠道路生命週期評估軟 體，作為道路工程碳排放量評估工具並參考 國際綠道路指標內容，建立綠道路設計綱要，
提升國內業者在綠道路規劃設計能力。成果 極具應用潛力，符合政府節能減碳政策。
近年工業上應用機器人於自動焊接過程 已日益廣泛，例如車廠大量使用焊接機器人 進行車架成型與車輛組立，皆可大幅提升生 產效率與品質。可以說，藉由機械手臂在生 產過程中進行點銲或平面銲接的製程已十分 成熟與普遍，但也有許多製程因無法進行自 動銲接仍採用人工銲接，主因是現有專用銲 接手臂智能信息與整合功能化不足所致。環 顧國內業者、研究機構與學校尚無整合機械 手臂與各類自動化、半自動機具而能執行的 成功案例。目前國內尚未具備智能銲接整合 技術，因而此智能銲接整合技術的開發，對 於未來工廠生產效能與品質提升更形重要。
本計畫將開發一套機械手臂用於銲接
Nozzle 之智能作業系統，智能系統包含以下
三種功能：平面智能調整銲接系統、打底銲
接及多層多道銲接。若能完成此三種功能之
開發，將完成 Nozzle 的自動化銲接取代人
力。本系統開發成功後會是國內首座智能銲
接系統，將有效降低機械廠製造成本、提升
產品質量，預期未來將有許多應用商機。
每個生命體都宛如一座超精密的化學工 廠，裡面大大小小的化學物理反應皆環環相 扣相互影響，而對生命體而言，這複雜的系 統藍圖資訊就存在於 DNA 序列中。自 DNA 在 1869 年被瑞典生化學家米歇爾 (Friedrich Miescher) 發現，1953 年被兩位劍橋大學科 學家詹姆斯 • 沃森 (James Watson) 和弗朗西 斯 • 克里克 (Francis Crick) 解構後，科學家便 致力於解開這個生命密碼，希望能突破先天 的限制，或是修正異常基因。
從人類開始農耕畜牧以來，育種成了一 種普遍的方式，希望孕育出更符合需求的新 品種，從早期的篩選配種，到分子輔助育種，
進而到基因轉殖，以及最近新興崛起的基因 編輯。如果說 DNA 的定序是解開生命密碼的 序曲，近年備受關注的 CRISPR/Cas9 基因 技術則是一個非常強大的 DNA 編輯工具，不 但能幫助人們更深入了解生命體運作機制，
更可進一步經由基因體編輯達到育種的目 的，突破過往冗長的雜交育種程序，成為近 年來最受矚目，也發展最快的基因工程技術，
本文將就此基因編輯技術做一簡單介紹。
前言
一、 CRISPR/Cas9 基因編輯技術簡介 生命體除具有自我修復功能，還有一套 抵制外來病毒與細菌的免疫系統機制，小至細 菌也同樣有此功能。其中一個存在細菌與古 細菌中的後天免疫機制就是 CRISPR/Cas 系 統，此系統有兩個關鍵組成，一個是 CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats)，這是由相同的重複序 列 (repeat) 和不同的間隔序列 (spacer) 不斷重 複所形成；另一個是 Cas (CRISPR associated proteins)，是一種核酸酶 (nuclease)，CRISPR 基因座 (locus) 結構如圖一。
圖一、CRISPR 基因座結構
其運作機制是當每次有外來病毒入侵 時，如果細菌存活下來，便會把病毒遺留 的 DNA 片段加到自己的 CRISPR 序列中成 為一段 spacer 留下紀錄，所以 spacer 記載 了不同病毒的基因片段序列，且越新捕獲 的病毒序列，就會越靠近前導序列 (leader sequence)，有越早做比對的作用，當下一 次遭受到曾記載過的病毒侵略時， CRISPR/
Cas 系 統 會 自 動 將 此 病 毒 的 DNA 轉 錄 成 RNA 型式來做比對，稱之為 CRISPR RNA (crRNA)，有時還會需要另一段特別的 RNA 來調控 crRNA 活性，稱之為 trans-activating RNA (tracrRNA)，來幫助尋找病毒的 DNA，
兩個 RNA 結合成一個 guide RNA (gRNA)，
找到互補的病毒 DNA 後形成一個標示，誘 導 Cas 進行水解，達到防禦效果，這就是整 個免疫系統基本的運作方式，如圖二。
不同細菌種類所擁有的 CRISPR/Cas 系 統不盡全然相同，大致上可粗分為 Type I、II 和 III 三大類型，Type I 與 Type II 的作用目標 為 DNA，而 Type III 的目標則為 DNA 與 ( 或 ) RNA。Type I 與 Type III 兩者都只需 crRNA 就可辨識病毒 DNA，但須多種 Cas 參與，
並先形成一個複雜的蛋白複合體 (Cascade- like complex) 來 辨 識 與 分 解 病 毒 DNA；
Type II 的機制較為簡易些，僅須透過 Cas9 核酸內切酶 (endonuclease) 結合 crRNA 與 tracrRNA 形成的複合體，就可進行辨識與分 解功能，亦稱之為 CRISPR/Cas9 系統，當 今生技領域最受關注並寄予厚望的基因編輯 技術就是從此系統衍生而來。
目前 CRISPR/Cas9 基因編輯技術，主要
是透過一個來自化膿性鏈球菌 (Streptococcus
pyogenes) 的 Cas9 核酸內切酶與 crRNA 與
tracrRNA 形成的複合體，藉由 tracrRNA 及
設計與目標序列互補的 crRNA 黏合為一單股
RNA，稱為 single guide RNA (sgRNA)，引導
Cas9 核酸內切酶到 DNA 序列中想要進行編
輯的位置進行編輯。
二、 CRISPR/Cas9 基因編輯技術之優點
三、 CRISPR/Cas9 基因編輯技術之脫靶 效應
CRISPR/Cas9 技術之所以被稱為引發 基因編輯大革命之史上功力強大的基因編輯 技術，主要是此技術具有下列幾項優點 : 1.
2.
3.
4.
可應用層面廣：此技術並無物種的限制，
舉凡從微生物、植物到動物，皆可藉由此 技術達到優化動物和作物育種的目標。
製程簡單：只須對兩種 RNA 進行人工設 計，即可對欲修改的基因序列進行編輯。
準確性高：以往的編輯工具無法很準確定 位，但此技術利用 DNA 與 RNA 鹼基互補 配對原則，提高定位與編輯準確率。
時程短：撇開過去傳統育種，動輒耗費數 年不說，早期的基因編輯技術，用來標的 蛋白質不易製作，且實驗流程繁複，往往 需耗時一年多，而此技術平均數周即達到
綜觀上述優點，不難想像各領域之研 究人員對 CRISPR 技術的未來應用發展上 充滿想像，但事情通常不會只有好的一面，
接下來就來談談此技術發展關鍵阻礙之一 的脫靶（ off target）效應。在前文中，曾簡 介 CRISPR 基因編輯技術的原理和機制，了 解到這個技術是仿造生命體免疫 (CRISPR/
Cas) 系統的概念而來，而這個免疫系統主要 功能是進行敵我辨識，稍作比對後對外來基
圖二、CRISPR/Cas 系統運作機制 來源: 轉譯自 Welgene Biotech Co., Ltd.
