Vegetation water-soluble polysaccharide from
Cordyceps composition and physiological activity of eng
Chemical composition and physiological activities of water-soluble polysaccharide from phytocordyceps ninchukispora Su et Wang
AbstractChinese caterpillar fungus spores nunchakus vegetation (Phytocordyceps ninchukispora Suet Wang) is Clavicipitaceae ball
Globosum projects, nuclear Basidiomycetes, system is the recent discovery of new vegetation in Taiwan Chinese caterpillar fungus (Phytocordyceps) of a single type, the paper
Use this strain for its chemical composition analysis of
polysaccharide and biological activities of the research to collect the liquid culture
Medium supernatant after centrifugation, using ultra filter, molecular sieve and ion exchange, purification of the culture medium
In the macromolecular polysaccharides can be divided into water insoluble (PNI) and water soluble (PNS) of two parts. This is still for the water-soluble
Of part (PNS) for analysis of chemical composition and physical activity. The order of mineral acid (2N HCI) and trifluoroacetic acid hydrolysis (
trifluoroacetic acid) hydrolysis showed that this polysaccharide is mainly composed by the N-acetylqlucosamine,
The hydrolysates made by the TMS derivatives, with its GC-mass analysis showed that, the other containing a small amount of Galactose,
Mannose and Threitol, to nuclear magnetic resonance (NMR) show that N-acetylqlucosamine, with β -1,
4 way bonding. Sarcoma-180 mice to transfer resistance to artificial test. Showed that oral administration of 50 ㎎ / kg
/ Day dose, it can be to reduce the number of lung tumors to 50% or less, to HL-60 leukemia cells in vitro show
, PNS can increase the number of cell colony, but did not induce cell differentiation functions, at the same time with other Cytokine
In comparison, suggests that the nature of their similar Cytokine. In Flow cytometry analysis, also suggests that PNS
The mouse peripheral blood of Total T-1ymphocyte and T-helper 1ymphocyte have hao with elevated
Effect.
