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Oral Oncology Extra 42, 227230 (2006)
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Case history
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Figure 3 (A) CK positive in squamous and non-squamous areas and
(B) CEA positivity in the squamous areas
Discussion
TumourÎ T base of tongue,Ï eadenoid cystic pattern8,eR Ð Ñ Ò (i) True adenoid cystic tumour of the salivary gland
z Ó 4£ small darkly stained uniform cellsÔ Õ F Ö × ¤ ,F , lumina of these spacesØ Ù Ú £ myoepithelial cells¤ Û Ü hyaline material or basement membrane material. keratin. Immunohistochemistry ~ CEA : postivity only in the ductal
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cells.
(ii) Mixed parotid tumour
4Ý Þ f ¢ .Ý Þ 8X ß à á à R4ACC.
(iii) Basaloid squamous carcinoma with adenoid cystic pattern
esolid nests of poorly differentiated cells in lobular form,â ã 8ä ¨ bmucosaå d. ª « ¥ ¦ escantly cytoplasm with dark hyperchromatic nuclei without nucleoli Rsmall cystic spaces,´ adenoid cystic carcinoma5 7 .ª Ñ f ¢ æ ç > e\X Û 8squamous component,è C é ê squamous carcinoma.
6` ® adenoid spaces4â B C 8,ësitu squamous component and keratin pearls 8@ A4Ê ì í H I : squamous carcinoma.î ï ð J ñ ª « ò ó ,ë
Z Û ô Å â eõ ö 8ACC? bbasaloid cells\z å A S100protein, actin, and vimentin, · b60%–90% 8÷ ® , CEAø bductal cells@ A.
ù ú 8q A eö T Z Û ô Å ,BSCû ü hypopharynx, base of tongue, larynx or tonsilRý þ cervical lymph node metastasis.
BSC8Stage, behavior and treatment > ´8squamous cell carcinoma.5 7 .
» : Surgery with neck node dissection with or without radiotherapy.
M N » 8 4 G BSC and ACCÄ Å » 5 7 ò ó 8X ß , Rimmunohistochemistry8O Þ ,ò [ 46; < } ekeratinsitu squamous carcinoma component ò ó .
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Oral Oncology EXTRA (2006) 42, P. 229
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