prognosis of ameloblastoma could be evaluated by the radiographic boundary
The ameloblastoma cases treated by the conservative therapy in our hospital between 1981 and 2001 were divided into three groups based on the nature of the radiographic borders of the lesions. The biologic behavior was evaluated by Ki-67 antibody immunohistochemically.
Comparisons of prognosis and Ki-67 expression were carried out by statistic methods.
There were 24 cases of well-defined edge with sclerosis (group I), 41 cases of well-defined edgewithout sclerosis (group II) and 32 cases of ill-defined edge (group III). The recurrent rates were 29.2% in group I, 43.9% in group IIand 62.5% in group III (P,0.05)
The cells in group III expressed the highest Ki-67 level (P,0.05). The radiographic boundary could be used as one of indicators in evaluating the proliferative ability of ameloblastoma and the patient’s prognosis, which was consistentwith Ki-67 expression
Introduction:
• Ameloblastoma is a benign odontogenic tumor with an aggressive biological behavior
• It was found that ameloblastomas of different radiographic appearances had not similar biological behaviors
Material and methods
ameloblastoma cases of the last 20 years retrieved from the files of West China Stomatology Hospital of Sichuan University between 1981 and 2001 and focused on the patients who received a conservative treatment
Panoramics of all patients were reviewed as the basic method to evaluate the radiographic boundaries and gain other information such as the size and location of the lesions. If necessary, computer tomography was employed to assist in providing the information in the buccolingual direction
(a) Group I: well-defined edge with sclerosis
group I presented a confine dradiolucent lesion with a sharp edge and a sclerotic line existing inmore than 80% of the border between the normal bone and the lesion
(b) group II: well-defined edge without sclerosis
group II was a confined radiolucent lesion with a sharp edge which was similar to that of group I, but with a sclerotic line existing in less than 20% of the border
81).
(a) Group I: well-defined edge with sclerosis
(b) group II: well-defined edge without sclerosis
(c) group III: ill-defined edge Discussion :
題號 題目
1 何種形態的 ameloblastoma 好發率最高？
(A) Conventional / multicystic (B) Unicystic
(C) Peripheral (extraosseous)
答案(A ) 出處：Oral and maxillofacial pathology 2nd Edition
題號 題目
2 Which one of the following statement about unicystic ameloblastoma is wrong ?
(A) Account for 10~15% of intraosseous ameloblastoma (B) Usually found in posterior maxilla
(C) Often seen in young patient (D) Often asymptomatic
答案(B) 出處：Oral and maxillofacial pathology 2nd Edition
