Ji3cl3 原文題目(出 處)：
Epithelial-myoepithelial carcinoma of the tongue base: a case for the case-report and review of the literature Head &
Neck Oncology 2010;2:4
原文作者姓名： Peter Peters, Costa Repanos, James Earnshaw, Patrick Stark, Bryan Burmeister, Lloyd McGuire, Susanne Jeavons,
William B Coman AM
通訊作者學校： Department of Otolaryngology Head and Neck Surgery, Princess Alexandra Hospital, Ipswich Rd, Woolloongabba, Queensland, Australia
報告者姓名(組別)： 周煥珵 (Intern B 組)
報告日期： 99.9.13
內文：
Introduction:
Epithelial-myoepithelial carcinoma is a rare tumour occurring in the salivary glands (parotid gland)
0.2% ~1% of salivary duct tumours
hybrid tumour:
1965 ~1994 0.1% of salivary gland tumours were hybrid tumours
Mucoepidermoid carcinoma, basaloid-squamous carcinoma, adeno-squamous carcinoma, sarcomatoid carcinoma and carcinoma in pleomorphic adenoma with differentiation as squamous cell carcinoma as well as adenocarcino
Case Report
A 60 year old lady was referred to the Princess Alexandra Hospital Head and Neck Clinic
biopsy taken from a suspected tumour at the base of the tongue (BOT) a one year history of dysphagia and difficulty in moving her tongue 25 kg weight loss over the past year
PEG feeding tube inserted
vertical length of the tumour was 3.7 cm
BOT tumour are not typical for the more common SCC in this location with the irregular bright T2 signal
unusual SCC appearance > minor salivary gland rare tumour
epithelial-myoepithelial carcinoma of the tongue base
60 Gy treatment over 30 fractions with a 2 cm margin around the primary tumour daily hyoscine injections to dry up excessive secretions
Literature Review
Discussion
Site:
p63 SMA
(2)Luminal epithelial cell layer AE1/AE3
CK5/6
Low grade malignant tumours
high grade tumours show evidence of dedifferentiation recurrence rate 41%
5 year survival rate 87.5%
10 year survival rate 67.5%
題號 題目
1 Which is the most common malignant mixed tumor?
(A) carcinosarcoma
(B) Carcinoma ex pleomorphic adenoma (C) Metastasizing mixed tumor
(D) pleomorphic adenoma 答案
(B)
出處：Oral and Maxillofacial Pathology second edition p.424
題號 題目
2 Which is the more common site to be seen?
(A) Submandibular gland (B) Sublingual gland (C) Parotid gland
(D) Minor salivary gland 答案
(C)
出處：Oral and Maxillofacial Pathology second edition p.425
