Indica rice and exogenous cholesterol with or without hypercholesterolemia cholesterol metabolism in rats
Effects of Indica rice and exogenous cholesterol on cholesterol metabolism in rats with or without hypercholesterolemia
Abstract
This study investigated the long rice (Taichung Native 1) of polished rice and brown rice as the carbohydrate source for large
Rat serum and liver cholesterol metabolism. Wistar male rats to 84 (? 370 g
) Were randomly divided into 7 groups (1 control, 6 experimental).
To feed no cholesterol (0%, w / w) corn
Starch as the control group rats, and the remaining 6 experimental groups were no intake or high (1%, w / w) cholesterol
Alcohol corn starch, refined white rice and brown rice diet for 4 weeks (Experiment Ⅰ), collecting the last 7 days faeces
Arbitrarily take half of the rats in each group the serum and liver samples. The remaining rats continued feeding, in addition to
Control group, the original intake of cholesterol-free experimental group fed high-cholesterol diet change; the original intake of high cholesterol
Alcohol in the experimental group fed no cholesterol diet change, and then to 4 weeks to feed and collect the sample (experimental Ⅱ)
. Fecal dry weight, serum total cholesterol (TC), low density lipoprotein cholesterol (LDL - C
), High density lipoprotein cholesterol (HDL - C), triglycerides (TG), phospholipids and liver
TC, TG and total lipid (TL). Feeding groups and fed polished white rice brown rice dry weight in feces were significantly higher than the feed-yu
Rice starch group. Ⅰ in experimental rats fed no cholesterol, the feeding of fine rice group HDL - C / LDL - C was
The control group; feeding brown rice serum TG concentrations were significantly lower than the control group. Cholesterol feeding in experimental Ⅰ
Rats in comparison with the group fed corn starch, fed group and fed brown rice polished rice can significantly lower blood group
Qing TC, LDL - C concentration and liver TC and TL concentration can significantly improve HDL - C / LDL - C ratio, only
Feeding significantly reduced serum TG brown group concentration.
In the experiment Ⅱ in rats fed cholesterol, by and feed corn
Starch group, feeding groups and fed polished white rice brown rice group can significantly enhance the HDL - C / LDL - C ratio
And significantly decreased serum TC, LDL - C and liver TC and TL concentration; only group to significantly reduce feeding brown rice
Serum TG concentration. Experiment Ⅱ rats fed cholesterol-free, the group with feed corn starch, refined white feeding
Brown rice group and the group can significantly enhance the feeding HDL - C / LDL - C ratio, only feed brown rice group had a higher blood
Qing HDL - C and TG concentrations; feed corn starch in liver TC, TG, and TL were significantly higher concentrations,
Feeding groups and fed polished white rice brown rice group and control group are similar. Among them, feeding of liver TG
concentration in brown rice also significantly
Lower than the group fed polished rice. These results show that:
brown rice to increase the role of fecal dry weight maximum. In real
Ⅰ experience when fed non-cholesterol diet, refined white rice and brown rice can not show significant cholesterol-lowering effect.
Ⅰ in experimental diets fed cholesterol; or in the fed cholesterol- free diet, then fed cholesterol diets,
Polished rice and brown rice are significantly better than the
cholesterol-lowering effect of corn starch. In the cholesterol diet for 4 weeks after feeding
, Remove the feed cholesterol, refined white rice and brown rice can be reduced to control cholesterol levels in rats
The same group, and brown rice than white rice.
