[PDF] Top 20 Effects of Thyroid Hormone on the Arrhythmogenic Activity of Pulmonary Vein Cardiomyocytes

... The ionic current experiments showed that hyperthyroid PV beating cardiomyocytes had larger densities of overall slow inward (2.72 +/- 0.21 pA/pF vs. By contrast, the hyperthyroid PV n[r] ... See full document

... investigate the effects of thyroid hormone on the electrophysiological characteristics of pulmonary vein (PV) ...etiology of paroxysmal atrial ... See full document

... This study demonstrated that PV cardiomyocytes have an increase in arrhythmogenic activity at high temperatures because of enhanced automaticity, induced triggered activity, or shorten[r] ... See full document

... PV cardiomyocytes with and without pacemaker activity had larger pacemaker currents at higher ...PV cardiomyocytes have an increase in arrhythmogenic activity at high temperatures ... See full document

... Chen YJ; Chen YC; Wongcharoen W; Lin CI; Chen SA; 貢獻者:臨床醫學研究所 上傳時間:2009-08-21T08:58:20Z 摘要:Pulmonary veins are the most important focus for the generation of atrial fibrillation. Abnormal ... See full document

... Methods and Results - The action potential and ionic currents were in- vestigated in PV cardiomyocytes from control and long-term (6 to 8 weeks) RAP (780 bpm) dogs by use of the whole-ce[r] ... See full document

... Background— Pulmonary veins (PVs) are important sources of paroxysmal atrial ...facilitates the maintenance of atrial ...alters the arrhythmogenic activity of PVs. ... See full document

... increasing arrhythmogenic activity of pulmonary vein ...Using the whole-cell clamp technique, the action potential and ionic currents were investigated in rabbit single ... See full document

... in the pacemaker activity of cardiomyocytes has been ...obscure. The results of this study first showed that cell swelling may reduce the PV firing ...in the PV ... See full document

... control. The insets in the cur- rent traces show the various clamp ...Effect of Endothelin-1 on the PV Electrical Activity Endothelin-1 has negative chronotropic ... See full document

... prevented the chrono-inhibitory effects of endothelin-1 (10 ...reduced the L-type calcium currents, transient outward currents, delayed rectifier currents, transient inward currents, and ... See full document

... Introduction: The fraction- ated atrial electrogram, a signal helpful in identifying the target site for radiofrequency catheter ablation of the slow AV nodal pathway, is considered to arise ... See full document

... Gadolinium and streptomycin (stretch-activated ion channel blockers) were each perfused into the pulmonary veins under a 300-mg stretch. CONCLUSION: Stretch is an important factor in [r] ... See full document

... METHODS: The transmembrane action potentials were recorded from rabbit pulmonary veins before and after stretch (100 and 300 mg). Gadolinium and streptomycin (stretch-activated ion chann[r] ... See full document

... mechano-electrical effects. Objective: To investigate whether stretch can increase the arrhythmogenic activity of the pulmonary ...Methods: The transmembrane action ... See full document

... CONCLUSIONS: We conclude that I(Ca-T) contributes to PV pacemaker activity and triggered activity, which are of functional importance in PV arrhythmogenesis.[r] ... See full document

... T-type Calcium Current in Electrical Activity of Cardiomyocytes Isolated from Rabbit Pulmonary Vein.. 陳亦仁.[r] ... See full document

... purposes of this study were to evaluate the electrophysiological difference and ion channel properties between mononucleated and binucleated cardiomyocytes in LA and ...rabbits of 3months old ... See full document

... BACKGROUND: The superior vena cava (SVC) has been proved to be a focal point in the initiation of paroxysmal atrial ...fibrillation. The autonomic nervous system plays an important role in ... See full document

... 4.Angiotensin II reduced the transient outward potassium current (Ito) but increased the L-type calcium, delayed rectifier potassium (IK), transient inward (Iti), pacemaker, and Na+–Ca[r] ... See full document