[PDF] Top 20 Endothelin-1 enhances cell migration through COX-2 up-regulation in human chondrosarcoma

... (PGs). COX-2 is an inducible enzyme and is activated by extracellular stimuli such as growth factors and pro- inflammatory cytokines ...of COX-2 is frequently found in many types of ... See full document

... implicated in the regulation of a number of cellular processes, including adhesion, signaling, motility, survival, gene expression, growth, and differentiation .... In the present study, BDNF ... See full document

... dimerization through their leucine zipper ...phosphorylation. In addition, c-Jun siRNA abolished the CCN6-induced cell migration in chondrosarcoma ...act through the FAK, ... See full document

... of chondrosarcoma remains ...and migration. Stimulation of chondrosarcoma cells with ET-1 induced mRNA and protein expression of EMT marker such as N-cadherin and ...of chondrosarcoma ... See full document

... increase in NF-B ...kinases through various signaling pathways, and this enhances the p65 transactivation ...role in the expression of v3 integrin and cell migration of ... See full document

... that up-regulation of EDN1 in HCC may be caused by a down-regulation of miR-1 in these ...HCC. In Asia, more than 80% of HCC cases are due to infection with HBV or ... See full document

... the migration of chondrosarcoma ...IGF-I-directed migration was up-regulation of DE integrin and activation of IGF-IR, PI3K, Akt, and NF-NB ...2009). Human cancer cells express ... See full document

... Abstract Chondrosarcoma is a malignant tumor that produces cartilage ...upregulated in highly aggressive ...suppressed cell migration. Exogenous AR markedly increased cell ... See full document

... expressed in human osteosarcoma cell lines but was not expressed in normal osteoblast samples ...metastasis in osteosarcomas, suggesting that BMP pathway may participate in tumor ... See full document

... CTGF enhances migration and MMP-13 up-regulation via alphavbeta3 integrin, FAK, ERK, and NF-kappaB-dependent pathway in human chondrosarcoma ...J Cell Bio- chem ... See full document

... molecule- 1 up-regulation in bradykinin promotes cell motility in human prostate ...malignancy in men and shows a predilection for metastasis to distant ...cancer ... See full document

... promote cell migration in human chondrosarcoma cells through OBR1/IRS-1/PI3K/Akt/NF-�B pathways ...leptin in regulating VEGF expression, which potentiates ... See full document

... preventing chondrosarcoma metastasis. Previous studies have shown that CCN1 (Cyr61) and CCN2 (CTGF) modulates cell migration and invasion in human chondrosarcoma ... See full document

... step in cancer migration and invasion. MMP-1, -2, -3, -9, and -13 have been found to regulate metastasis of human chondrosarcoma ...involved in HGF-mediated cell ... See full document

... protein 1, WISP-1), CCN5 (WISP-2), and CCN6 (WISP-3) ...cellular migration, adhesion, proliferation, extracellular matrix (ECM) formation, and regulation of tumorigenesis ...expression ... See full document

... ABSTRACT Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...protein 1 (HMGB)-1 is a widely studied, ubiquitous nuclear protein that is ... See full document

... induced COX-2 expres- sion through AP-1 dependent pathway ...NOV-induced migration and COX-2 expression in osteosarcoma ...dimerization through their leucine ... See full document

... increases migration of human lung cancer cells through intercellular adhesion molecule-1 up-regulation Li-Mien Chen 1,2 , Chia-Hua Kuo 3 , Tung-Yuan Lai 4,5 , ... See full document

... process in which secondary tumors are formed in distant sites ...attachment in the target organ, invasion of the target organ by extravasation, and proliferation within the organ parenchyma ...cancer ... See full document

... Tumor malignancy is associated with several cellular properties including proliferation and ability to metastasize. Resistin the most potent pro-inflammatory and plays a crucial role in migration and ... See full document