• 沒有找到結果。

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26. Bhatt A, Glehen O. The role of Cytoreductive Surgery and Hyperthermic

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27. Bakrin N, Classe JM, Pomel C, Gouy S, Chene G, Glehen O. Hyperthermic

intraperitoneal chemotherapy (HIPEC) in ovarian cancer. Journal of visceral surgery 2014; 151(5): 347-353.

28. Glehen O, Mohamed F, Gilly FN. Peritoneal carcinomatosis from digestive tract cancer: new management by cytoreductive surgery and intraperitoneal

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30. Mulier S, Claes JP, Dierieck V, et al. Survival benefit of adding Hyperthermic IntraPEritoneal Chemotherapy (HIPEC) at the different time-points of treatment of ovarian cancer: review of evidence. Current pharmaceutical design 2012; 18(25):

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32. Canadian Agency for Drugs and Technologies in Health.

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33. Medical Services Advisory Committee.

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35. Public Health England. Clinical governance.

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PRODIGE 7. American Society of Clinical Oncology.

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48. Rudloff U, Langan RC, Mullinax JE, et al. Impact of maximal cytoreductive surgery plus regional heated intraperitoneal chemotherapy (HIPEC) on outcome of patients with peritoneal carcinomatosis of gastric origin: results of the GYMSSA trial. Journal of surgical oncology 2014; 110(3): 275-284.

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醫療科技評估報告補充資料

附錄

附錄一、「腹腔溫熱灌注管路組」建議給付規定

1. 須事前審查,提供 3 個月內之電腻斷層、核磁共振或正子掃描等影像檢查,確 認無腹膜以外轉移病灶。

2. 限有病理報告證明為下列疾病,可接受腫瘤減量手術後,同時施行腹腔內熱化 療:闌尾黏液癌(pseudomyxoma peritonei)、大腸直腸癌(colorectal cancer)、腹膜 間皮瘤(peritoneal mesothelioma)、胃癌(gastric cancer)、卵巢癌(ovarian cancer)。

3. 手術者須預期前述 5 項腫瘤接受減容手術前無腹膜外轉移,術中可完成適當的 減容手術者(即殘存腫瘤直徑小於 0.25 公分以下)。

4. 需記錄術中下列資料,包括該次手術腹腔轉移及切除器官之相關病理報告、腹 腔內溫度/時間記錄表、手術記錄及彩色相片。

5. 每次限使用腹腔溫熱灌注治療套組 1 組,灌注導管最多使用 4 條。

醫療科技評估報告補充資料

附錄二、療效評估文獻搜尋策略

1. 腹膜假黏液瘤

Cochrane Library

查詢日期 編號 關鍵字 篇數

2018/10/18 #1 MeSH descriptor: [Pseudomyxoma Peritonei] explode all trees 2

#2

"Pseudomyxoma peritonei" or "peritoneum pseudomyxoma" or

"peritoneal pseudomyxoma " 16

#3 #1 or #2 16

#4 MeSH descriptor: [Hyperthermia, Induced] explode all trees 1464

#5

HIPEC or "hyperthermic intraperitoneal chemotherapy" or "heated intraoperative intraperitoneal chemotherapy" or "intraperitoneal chemotherapy" or "intraoperative chemotherapy" or "intraperitoneal heated chemotherapy" or "hyperthermic intraperitoneal chemoperfusion"

"pseudomyxoma peritonei"[MeSH Terms] OR ("pseudomyxoma"[All Fields] AND "peritonei"[All Fields]) OR

"pseudomyxoma peritonei"[All Fields] OR (("peritoneum"[MeSH Terms] OR "peritoneum"[All Fields]) AND pseudomyxoma[All Fields])

1539

#2 "hyperthermia, induced"[MeSH Terms] 29266

#3

"hyperthermic intraperitoneal chemotherapy"[All Fields] OR

"heated intraoperative intraperitoneal chemotherapy"[All Fields]

OR "intraperitoneal chemotherapy"[All Fields] OR "intraoperative chemotherapy"[All Fields] OR "intraperitoneal heated chemotherapy"[All Fields] OR "hyperthermic intraperitoneal chemoperfusion"[All Fields]

3144

#4

"cytoreduction surgical procedures"[MeSH Terms] OR ("cytoreduction"[All Fields] AND "surgical"[All Fields] AND

"procedures"[All Fields]) OR "cytoreduction surgical procedures"[All Fields] OR ("cytoreductive"[All Fields] AND

"surgery"[All Fields]) OR "cytoreductive surgery"[All Fields] OR cytoreduction[All Fields]

7257

#5 (#2 OR #3) AND #4 2121

醫療科技評估報告補充資料

#6 #1 AND #5 351

#7 #6 AND (systematic[sb] OR Randomized Controlled Trial[ptyp]

OR Meta-Analysis[ptyp])

'pseudomyxoma peritonei'/exp OR 'pseudomyxoma peritonei' OR (('pseudomyxoma'/exp OR pseudomyxoma) AND peritonei) OR 'peritoneum pseudomyxoma'/exp OR 'peritoneum pseudomyxoma'

2231

#2

'hyperthermic intraperitoneal chemotherapy' OR 'heated intraoperative intraperitoneal chemotherapy' OR 'intraperitoneal chemotherapy' OR 'intraoperative chemotherapy' OR 'intraperitoneal heated chemotherapy' OR 'hyperthermic intraperitoneal chemoperfusion'

5001

#3 'cytoreductive surgery' OR cytoreduction 16934

#4 #1 AND #2 AND #3 544

#5

#4 AND ([cochrane review]/lim OR [systematic review]/lim OR [meta analysis]/lim OR [controlled clinical trial]/lim OR [randomized controlled trial]/lim)

16

2. 大腸直腸癌

Cochrane Library

查詢日期 編號 關鍵字 篇數

2018/10/18 #1 MeSH descriptor: [Colorectal Neoplasms] explode all trees 6876

#2 "colorectal cancer" or "colon cancer" 10534

#3 MeSH descriptor: [Peritoneal Neoplasms] explode all trees 274

#4

"peritoneal carcinomatosis" or "peritoneal carcinomatoses" or

"peritoneal metastasis" or "peritoneal metastases" 332

#5 (#1 or #2) and (#3 or #4) 109

#6 MeSH descriptor: [Hyperthermia, Induced] explode all trees 1464

#7

HIPEC or "hyperthermic intraperitoneal chemotherapy" or "heated intraoperative intraperitoneal chemotherapy" or "intraperitoneal chemotherapy" or "intraoperative chemotherapy" or "intraperitoneal heated chemotherapy" or "hyperthermic intraperitoneal chemoperfusion"

326

#8

MeSH descriptor: [Cytoreduction Surgical Procedures] explode all

trees 28

#9 "cytoreductive surgery" or "cytoreduction surgery" 662

醫療科技評估報告補充資料

#10 #5 and (#6 or #7) and (#8 or #9) 48

PubMed

查詢日期 編號 關鍵字 篇數

2018/10/18 #1 "colorectal neoplasms"[MeSH Terms] 184076

#2 "colorectal cancer"[All Fields] OR "colon cancer"[All Fields] 118439

#3 "peritoneal neoplasms"[MeSH Terms] 14724

#4

"peritoneal carcinomatosis"[All Fields] OR "peritoneal carcinomatoses"[All Fields] OR "peritoneal metastasis"[All Fields]

OR "peritoneal metastases"[All Fields]

5355

#5 (#1 OR #2) AND (#3 OR #4) 2147

#6 "hyperthermia, induced"[MeSH Terms] 29266

#7

"hyperthermic intraperitoneal chemotherapy"[All Fields] OR

"heated intraoperative intraperitoneal chemotherapy"[All Fields]

OR "intraperitoneal chemotherapy"[All Fields] OR "intraoperative chemotherapy"[All Fields] OR "intraperitoneal heated chemotherapy"[All Fields] OR "hyperthermic intraperitoneal chemoperfusion"[All Fields]

3144

#8

"cytoreduction surgical procedures"[MeSH Terms] OR ("cytoreduction"[All Fields] AND "surgical"[All Fields] AND

"procedures"[All Fields]) OR "cytoreduction surgical procedures"[All Fields] OR ("cytoreductive"[All Fields] AND

"surgery"[All Fields]) OR "cytoreductive surgery"[All Fields] OR cytoreduction[All Fields]

7257

#9 (#6 OR #7) AND #8 2121

#10 #5 AND #9 582

#11

#10 AND (Randomized Controlled Trial[ptyp] OR

Meta-Analysis[ptyp] OR systematic[sb]) 52 Embase

查詢日期 編號 關鍵字 篇數

2018/10/18 #1 'colorectal cancer' OR 'colon cancer' OR 'colorectal neoplasms' 237926

#2

'peritoneal carcinomatosis' OR 'peritoneal carcinomatoses' OR

'peritoneal metastasis' OR 'peritoneal metastases' 8010

#3

'hyperthermic intraperitoneal chemotherapy' OR 'heated intraoperative intraperitoneal chemotherapy' OR 'intraperitoneal chemotherapy' OR 'intraoperative chemotherapy' OR 'intraperitoneal heated chemotherapy' OR 'hyperthermic intraperitoneal chemoperfusion'

5001

#4 'cytoreductive surgery' OR cytoreduction 16934

醫療科技評估報告補充資料

#5 #1 AND #2 AND #3 AND #4 716

#6

#5 AND ([cochrane review]/lim OR [systematic review]/lim OR [meta analysis]/lim OR [controlled clinical trial]/lim OR [randomized controlled trial]/lim)

65

3. 胃癌

Cochrane Library

查詢日期 編號 關鍵字 篇數

2018/10/15 #1 MeSH descriptor: [Hyperthermia, Induced] explode all trees 1464

#2 Hyperthermic Intraperitoneal Chemotherapy 209

#3 heated intraoperative intraperitoneal chemotherapy 4

#4 #1 OR #2 OR #3 1642

#5 MeSH descriptor: [Stomach Neoplasms] explode all trees 2205

#6 gastric OR #5 20820

#7 #4 AND #6 82

PubMed

查詢日期 編號 關鍵字 篇數

2018/10/15 #1 Search "Hyperthermia, Induced"[Mesh] 29231

#2 Search "Stomach Neoplasms"[Mesh] 89601

#3 Search ("Hyperthermia, Induced"[Mesh]) AND "Stomach Neoplasms"[Mesh]

335

#4

Search ("Hyperthermia, Induced"[Mesh]) AND "Stomach Neoplasms"[Mesh] Filters: Randomized Controlled Trial;

Meta-Analysis; Systematic Reviews

40

#5

Search (Hyperthermic Intraperitoneal Chemotherapy) OR heated intraoperative intraperitoneal chemotherapy

36214

#6 Search gastric 380038

#7 Search (((Hyperthermic Intraperitoneal Chemotherapy) OR heated intraoperative intraperitoneal chemotherapy)) AND gastric

747

#8

Search (((Hyperthermic Intraperitoneal Chemotherapy) OR heated intraoperative intraperitoneal chemotherapy)) AND gastric Filters:

Publication date from 2018/01/01 to 2018/12/31

31

#9

Search ((("Hyperthermia, Induced"[Mesh]) AND "Stomach Neoplasms"[Mesh] AND ( ( Randomized Controlled Trial[ptyp]

OR Meta-Analysis[ptyp] OR systematic[sb] ) ))) OR (((((Hyperthermic Intraperitoneal Chemotherapy) OR heated intraoperative intraperitoneal chemotherapy)) AND gastric) AND

70

醫療科技評估報告補充資料

( "2018/01/01"[PDat] : "2018/12/31"[PDat] )) Embase

查詢日期 編號 關鍵字 篇數

2018/10/15

#1

'hyperthermic intraperitoneal chemotherapy'/exp OR 'hyperthermic intraperitoneal chemotherapy' OR 'heated intraoperative intraperitoneal chemotherapy'

2546

#2 'thermochemotherapy'/exp OR 'thermochemotherapy' 359

#3 #1 OR #2 2905

#4 'stomach cancer'/exp OR 'stomach cancer' 108241

#5

#3 AND #4 AND ([cochrane review]/lim OR [systematic review]/lim OR [meta analysis]/lim OR [randomized controlled trial]/lim) AND ([article]/lim OR [article in press]/lim OR

Hyperthermic Intraperitoneal Chemotherapy, peritoneal

mesothelioma 9

#2 Hyperthermic Intraperitoneal Chemotherapy, peritoneal

mesothelioma (2013 至 2018 年) 7

PubMed

查詢日期 編號 關鍵字 篇數

2018/10/8、

#1

(("hyperthermia, induced"[MeSH Terms] OR ("hyperthermia"[All Fields] AND "induced"[All Fields]) OR "induced hyperthermia"[All Fields] OR ("hyperthermic"[All Fields] AND

"intraperitoneal"[All Fields] AND "chemotherapy"[All Fields]) OR

"hyperthermic intraperitoneal chemotherapy"[All Fields]) AND ("hyperthermia, induced"[MeSH Terms] OR ("hyperthermia"[All Fields] AND "induced"[All Fields]) OR "induced hyperthermia"[All Fields] OR "hipec"[All Fields]) AND ("peritoneum"[MeSH Terms] OR "peritoneum"[All Fields] OR

"peritoneal"[All Fields]) AND ("mesothelioma"[MeSH Terms] OR

"mesothelioma"[All Fields])) AND ("humans"[MeSH Terms] AND English[lang])

184

2018/10/10

#2 (("hyperthermia, induced"[MeSH Terms] OR ("hyperthermia"[All Fields] AND "induced"[All Fields]) OR "induced

94

醫療科技評估報告補充資料

hyperthermia"[All Fields] OR ("hyperthermic"[All Fields] AND

"intraperitoneal"[All Fields] AND "chemotherapy"[All Fields]) OR

"hyperthermic intraperitoneal chemotherapy"[All Fields]) AND ("hyperthermia, induced"[MeSH Terms] OR ("hyperthermia"[All Fields] AND "induced"[All Fields]) OR "induced hyperthermia"[All Fields] OR "hipec"[All Fields]) AND ("peritoneum"[MeSH Terms] OR "peritoneum"[All Fields] OR

"peritoneal"[All Fields]) AND ("mesothelioma"[MeSH Terms] OR

"mesothelioma"[All Fields])) AND ("humans"[MeSH Terms] AND English[lang]) AND (("2013/01/01"[PDAT] : "2018/12/31"[PDAT]) AND "humans"[MeSH Terms] AND English[lang] AND cancer[sb])

Embase

查詢日期 編號 關鍵字 篇數

2018/10/11

#1

hyperthermic AND intraperitoneal AND chemotherapy, AND

peritoneal AND mesothelioma 449

#2

('peritoneal mesothelioma, hyperthermic intraperitoneal chemotherapy' OR (peritoneal AND mesothelioma, AND hyperthermic AND intraperitoneal AND ('chemotherapy'/exp OR chemotherapy))) AND [humans]/lim AND ([article]/lim OR [article in press]/lim) AND [2013-2018]/py AND [english]/lim

126

5. 卵巢癌

Cochrane Library

查詢日期 編號 關鍵字 篇數

2018/10/8 #1 Hyperthermic Intraperitoneal Chemotherapy, ovarian 70

#2

Hyperthermic Intraperitoneal Chemotherapy, ovarian (2013 至 2018)

("hyperthermia, induced"[MeSH Terms] OR ("hyperthermia"[All Fields] AND "induced"[All Fields]) OR "induced hyperthermia"[All Fields] OR ("hyperthermic"[All Fields] AND

"intraperitoneal"[All Fields] AND "chemotherapy"[All Fields]) OR

"hyperthermic intraperitoneal chemotherapy"[All Fields]) AND ("ovarian neoplasms"[MeSH Terms] OR ("ovarian"[All Fields]

AND "neoplasms"[All Fields]) OR "ovarian neoplasms"[All Fields]

OR ("ovarian"[All Fields] AND "cancer"[All Fields]) OR "ovarian

638

醫療科技評估報告補充資料

cancer"[All Fields]) 2018/1010

#2

("hyperthermia, induced"[MeSH Terms] OR ("hyperthermia"[All Fields] AND "induced"[All Fields]) OR "induced hyperthermia"[All Fields] OR ("hyperthermic"[All Fields] AND

"intraperitoneal"[All Fields] AND "chemotherapy"[All Fields]) OR

"hyperthermic intraperitoneal chemotherapy"[All Fields]) AND ("ovarian neoplasms"[MeSH Terms] OR ("ovarian"[All Fields]

AND "neoplasms"[All Fields]) OR "ovarian neoplasms"[All Fields]

OR ("ovarian"[All Fields] AND "cancer"[All Fields]) OR "ovarian cancer"[All Fields]) AND (("2013/01/01"[PDAT] :

"2018/12/31"[PDAT]) AND "humans"[MeSH Terms] AND English[lang] AND cancer[sb])

224

Embase

查詢日期 編號 關鍵字 篇數

2018/10/8

#1

hyperthermic intraperitoneal chemotherapy, ovarian cancer' OR (hyperthermic AND intraperitoneal AND chemotherapy, AND ovarian AND ('cancer'/exp OR cancer))

708

#2

hyperthermic AND intraperitoneal AND chemotherapy, AND ovarian AND ([article]/lim OR [article in press]/lim) AND [english]/lim AND [humans]/lim

285

#3 #2 AND 'clinical article'/de 104

#4 #2 AND 'clinical article'/de AND [2013-2018]/py 52

#5

hyperthermic AND intraperitoneal AND chemotherapy, AND ovarian AND ([article]/lim OR [article in press]/lim) AND ([cochrane review]/lim OR [systematic review]/lim OR [meta analysis]/lim)

4

醫療科技評估報告補充資料

附錄三、經濟評估文獻搜尋策略

資料庫 查詢日期 關鍵字 篇數 篩選後篇數

Pubmed 2018.03.19 #1 Peritoneal Carcinomatosis

#2 Hyperthermic Intraperitoneal Chemotherapy

#3 (((cost-effectiveness analysis) OR cost-utility analysis) OR cost-benefit analysis) OR cost-minimization analysis

17 5

EMBASE 2018.03.19 #1 Peritoneal Carcinomatosis

#2 Hyperthermic Intraperitoneal Chemotherapy

#3 cost

28 1/ 4

 一篇重複於 pubmed 搜尋

 兩篇為同一 作者之不同 的研討會摘 要)

Cochrane 2018.03.19 #1 Peritoneal Carcinomatosis

#2 Hyperthermic Intraperitoneal Chemotherapy

#3 cost

2 1 (重複於 pubmed 搜尋)

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