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sM· › £¢ ¢@· ¢· @HgsttQIZ@ dna@ «fi› ›⁄@ ›¡@· ¢@ ·¢ » · fi›@fi£@ aromatic hydrocarbons. Br J Ind Med 1990;47:454-61.
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63. Turkall RM, Skowronski GA, Kadry AM, et al. A comparative study of the kinetics and bioavailability of pure and soil-adsorbed naphthalene in dermally exposed male rats. Arch Environ Contam Toxicol 1994;26:504-9.
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67. Nan HM, Kim H, Lim HS, et al. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations. Carcinogenesis 2001;22:787-93.
68. Pavanello S, Clonfero E. Biological indicators of genotoxic risk and metabolic polymorphisms. Mutat Res 2000;463:285-308.
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71. Morris KCC. Comparative Distribution of Eight Polycyclic Aromatic Hydrocarbons in Airborne Particulates Collected by Conventional High-Volume Sampling and by Size Fractionation. Environ Sci Technol 1980;14:838-43.
72. Grimmer G, Schreider D. Changes in PAH profiles in different areas of a city during the year. In polynuclear aromatic hydrocarbons; chemistry and biological effect. Battelle press, Columbus 1983:107-25.
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WUN@ Siwinska E, Mielzynska D, Smolik E, et al. Evaluation of intra- and interindividual variation of urinary 1-hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons. Sci Total Environ 1998;217:175-83.
76. Mastrangelo G, Fadda E, Marzia V. Polycyclic aromatic hydrocarbons and cancer in man. Environ Health Perspect 1996;104:1166-70.
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WXN@ 衷劫危N@ス枢パ舗孰枢聰鎚彖婬譲Ε泳淕口淳釣ン瓜故Hpah I腿抽循檗麻苛 ピ屡幾N@単衣パ棹ス旱@淕卩ツ甫旱屡幾袈@圦シ扨δ RPPSN@
WYN@ Fang GC, Chen MH, Ho TT, et al. polycyclic aromatic hydrocarbons study in Taichung, Taiwan, during 2002-2003. Atmos Environ 2004;38:3385-91.
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XUN@ 琉鶏櫂N@ы膠穀杷派陸沢泳淕口淳鍈ン瓜故梧免ロ臥盛幗N@匣穀碼刀煮刈ス
旱@淕卩ツ甫壹煮旱屡幾袈@圦シ扨δ@RPPUN@
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XWN@ Huang W, Caudill SP, Grainger J, et al. Levels of 1-hydroxypyrene and other monohydroxy polycyclic aromatic hydrocarbons in children: a study based on U.S.
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XYN@ 峺展罷N@眩挨鍛ズ弯緻らα忘ピТ炬故壹窮李囲泣崩穴ピ疾穗勲屡幾N@パ単 痞碼ス旱@淕卩痞旱屡幾袈@圦シ扨δ@RPPSN@
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慌慌慌
慌慌慌
慌ヨヨヨヨ 弯緻会Ε堰裁会壹戴θ宰ョΕ戴θ宰唖仁免弯緻会Ε堰裁会壹戴θ宰ョΕ戴θ宰唖仁免弯緻会Ε堰裁会壹戴θ宰ョΕ戴θ宰唖仁免弯緻会Ε堰裁会壹戴θ宰ョΕ戴θ宰唖仁免(タ仁タ仁タ仁)ピπ儕タ仁 ピπ儕ピπ儕ピπ儕
@ 95 堰裁
(N=224)
96 堰裁 (N=117)
97 堰裁
(N=127) p1 95 堰裁 (N=201)
96 堰裁 (N=177)
97 堰裁
(N=144) p1 弯緻銅会
紅弯緻銅 19.9±4.5 19.3±3.5 0.506 4.6±4.5 5.1±3.4 0.623
弯緻銅 18.2±5.3 19.2±4.4 19.4±4.0 0.028 5.6±4.6 4.6±3.9 4.8±3.6 0.052
p2 0.227 0.897 0.974 0.75
* p 曙惨尉 ANOVA Ε T 泯緊垳Ь
慌慌
慌ろ慌ろ
慌慌慌
慌
慌んィ
慌 慌 慌
慌んペんペんペんペ 庵祷庵祷庵祷庵祷梶パ梶パ梶パ梶パ 1-OHP 朷裁壹朷裁壹朷裁壹窮棍喋朷裁壹窮棍喋窮棍喋窮棍喋姥址境外儿斥枯ピπ儕姥址境外儿斥枯ピπ儕姥址境外儿斥枯ピπ儕姥址境外儿斥枯ピπ儕
耨目 1-OHP(µg/L)
(N=556) p 1-OHP(µmol/mol cre.)
(N=556) p
狛匏斥枯 0.227 0.226
粉 0.020±0.038 0.021±0.036 鉛 0.026±0.053 0.028±0.083
狛恋斥枯 0.847 0.731
粉 0.022±0.044 0.023±0.051 鉛 0.018±0.019 0.019±0.020
哇勲γ枢古 0.299 0.702
粉 0.022±0.042 0.022±0.049 鉛 0.013±0.013 0.018±0.018
肇乢斥枯 0.512 0.667
粉 0.021±0.038 0.022±0.047 鉛 0.024±0.053 0.024±0.050
境外保行斥枯 0.911 0.714
粉 0.020±0.034 0.020±0.029 鉛 0.024±0.055 0.027±0.071
謡鴻壹礎杷惜戚 0.586 0.456
粉 0.020±0.030 0.021±0.029 鉛 0.030±0.083 0.032±0.108
COPD 0.096 0.187
粉 0.019±0.048 0.018±0.056 鉛 0.018±0.021 0.017±0.021
* p 曙惨尉枸衣 T 泯緊酋垳Ь
*1-OHP 鈎享吮彈痍媛阪酋垳 p 曙
慌ん 慌ん 慌ん
慌んヨヨヨヨ 庵祷庵祷庵祷庵祷梶パ梶パ梶パ梶パ窮窮窮窮 2-NP 朷裁壹朷裁壹朷裁壹窮棍喋朷裁壹窮棍喋窮棍喋姥址境外儿斥枯ピπ儕窮棍喋姥址境外儿斥枯ピπ儕姥址境外儿斥枯ピπ儕姥址境外儿斥枯ピπ儕
耨目 2-NP(µg/L)
(N=538) p 2-NP(µmol/mol cre.)
(N=538) p
狛匏斥枯 0.638 0.920
粉 2.60±3.79 2.61±3.55
鉛 2.58±3.12 2.35±2.13
狛恋斥枯 0.065 0.032
粉 2.43±3.20 2.42±3.03
鉛 3.34±5.40 3.23±4.60
哇勲γ枢古 0.856 0.498
粉 2.63±4.57 2.56±3.43
鉛 1.89±1.51 2.63±2.48
肇乢斥枯 0.205 0.211
粉 2.45±3.64 2.49±3.47
鉛 2.90±3.52 2.76±2.82
境外保行斥枯 0.972 0.539
粉 2.44±3.11 2.39±2.94
鉛 2.64±4.28 2.66±3.83
謡鴻壹礎杷惜戚 0.070 0.057
粉 2.44±3.20 2.44±3.00
鉛 3.25±5.70 3.12±4.87
COPD 0.369 0.174
粉 2.90±3.89 2.87±3.30
鉛 2.75±3.68 2.37±2.56
* p 曙惨尉枸衣 T 泯緊酋垳Ь
* 2-NP 鈎享吮彈痍媛阪酋垳 p 曙
慌慌
慌慌んんんんゅゅゅゅ 幀緲梶パ幀緲梶パ幀緲梶パ 1-OHP 壹幀緲梶パ 壹壹壹 2-NP 朷裁朷裁朷裁(µg/L)ピ泳朷裁 ピ泳ピ泳耨目慳勲賊珮ロ剣ピ泳耨目慳勲賊珮ロ剣耨目慳勲賊珮ロ剣耨目慳勲賊珮ロ剣
@ 耨目 1-OHP 朷裁
ぁ(S.E.) p 2-NP 朷裁@
ぁ(S.E.) p 堰裁
95 堰 3.206(1.186) <0.001 1.239(1.169) 0.243 96 堰 -2.692(1.183) <0.001 1.845(1.169) <0.001
97 堰 0 0
弯緻銅会
吮麟銅 0 0
弯緻銅 -1.829(1.219) 0.006 1.337(1.208) 0.045 堰粮(了)
<40 1.667(1.219) 0.015 -1.371(1.202) 0.136 40-70 1.230(1.172) 0.063 -1.197(1.159) 0.700
>70 0 0
外忘篤咢
粉 -1.574(1.183) 0.026 1.159(1.169) 0.317
鉛 0 0
惨械鉛ツ霞
粉 -1.079(1.161) 0.444 -1.194(1.151) 0.155
鉛 0 0
火丈嬰騨僮震
粉 -1.119(1.140) 0.345 1.076(1.130) 0.719
鉛 0 0
*1-OHP Ε 2-NP 鈎享吮彈痍媛
慌んろ 慌んろ 慌んろ
慌んろ 幀緲梶パ幀緲梶パ幀緲梶パ幀緲梶パ 1-OHP 壹壹壹壹 2-NP 朷裁朷裁朷裁朷裁(µmol/mol cre.)ピ泳耨目慳勲賊珮ロ剣ピ泳耨目慳勲賊珮ロ剣ピ泳耨目慳勲賊珮ロ剣ピ泳耨目慳勲賊珮ロ剣
耨目 1-OHP 朷裁
ぁ(S.E.) p 2-NP 朷裁
ぁ(S.E.) p 堰裁
95 堰 3.090(1.178) <0.001 1.233(1.164) 0.297 96 堰 -2.460(1.175) <0.001 1.941(1.164) <0.001
97 堰 0 0
弯緻銅会
吮麟銅 0 0
弯緻銅 -1.592(1.211) 0.041 1.592(1.202) 0.004 堰粮(了)
<40 1.637(1.211) 0.036 -1.380(1.197) 0.058 40-70 1.390(1.164) 0.055 -1.038(1.153) 0.817
>70 0 0
外忘篤咢
粉 -1.496(1.175) 0.016 1.236(1.164) 0.374
鉛 0 0
惨械鉛ツ霞
粉 1.021(1.156) 0.773 -1.079(1.148) 0.363
鉛 0 0
火丈嬰騨僮震
粉 -1.072(1.135) 0.556 1.114(1.127) 0.499
鉛 0 0
*1-OHP Ε 2-NP 鈎享吮彈痍媛
慌
OR 鮎扛暝 odds ration
慌慌
OR 鮎扛暝 odds ration
慌らんら慌らんら
梶パ 1-OHP 峨朷裁 <0.005µmol/mol cre. パ朷裁 0.005-0.021 µmol/mol cre. 堆朷裁 >0.021 µmol/mol cre.
梶パ 2-NP 峨朷裁 <1.17 µmol/mol cre. パ朷裁 1.17-2.37 µmol/mol cre. 堆朷裁 >2.37 µmol/mol cre.
慌らんィ慌らんィ
梶パ 1-OHP 峨朷裁 <0.005µmol/mol cre. パ朷裁 0.005-0.021 µmol/mol cre. 堆朷裁 >0.021 µmol/mol cre.
梶パ 2-NP 峨朷裁 <1.17 µmol/mol cre. パ朷裁 1.17-2.37 µmol/mol cre. 堆朷裁 >2.37 µmol/mol cre.
梶パ 1-OHP 峨朷裁 <0.005µmol/mol cre. パ朷裁 0.005-0.021 µmol/mol cre. 堆朷裁 >0.021 µmol/mol cre.
梶パ 2-NP 峨朷裁 <1.17 µmol/mol cre. パ朷裁 1.17-2.37 µmol/mol cre. 堆朷裁 >2.37 µmol/mol cre.
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