Association Between Periodontal Disease and Osteoporosis by Gender A Nationwide Population-Based Cohort Study
Tzu-Hsien Lin, PhD, Chia-Chi Lung, PhD, Hsun-Pi Su, PhD, Jing-Yang Huang, MS, Pei-Chieh Ko, MS, Shiou-Rung Jan, MS, Yi-Hua Sun, MS, Oswald Ndi Nfor, MS, Hsiao-Pei Tu, PhD, Chin-Shun Chang, DDS, MPH, PhD, FICD, Zhi-Hong Jian, MD, Yi-Chen Chiang, PhD, and Yung-Po Liaw, PhD
Abstract:
Periodontitis and osteoporosis are primary concerns in public health and clinical
management. The aim of this study was to investigate the association between periodontitis and osteoporosis by gender. Data were retrieved from the National Health Insurance
Research Database, Taiwan. A diagnosis of periodontitis was defined on the basis of subgingival curettage, periodontal flap operation, and gingivectomy (excluding those with restorative or aesthetic indications). Multiple logistic regression was used for analysis. After adjusting for age, sex, income, and geographical region, there was a significant association between periodontitis and osteoporosis among women (odds ratio: 1.96; 95% confidence interval 1.17–3.26). The association between periodontitis and osteoporosis was signifi- cant among women.
(Medicine 2015 94(7):e553)
Received: October 28, 2014; revised: January 20, 2015; accepted: January 22, 2015.
From the Department of Dental Hygiene (THL, HPS, HPT), China Medical University; Department of Public Health and Institute of Public Health (CCL, JYH, PCK, SRJ, YHS, ONN, ZHJ, YCC, YPL), Chung Shan Medical University; Department of Family and Community Medicine (CCL, YCC, YPL); Department of Dentistry (YHS), Chung Shan Medical University, Taichung; and Taiwan Society of Oral Health (CSC), Keelung, Taiwan.
Correspondence: Yung-Po Liaw, PhD, Department of Public Health and Institute of Public Health, Chung Shan Medical University, No. 110 Sec. 1 Jianguo N. Road, Taichung 40201, Taiwan (e-mail: Liawyp@ csmu.edu.tw).
