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Easy Interpretation of Heterotopic Ossification Demonstrated on Bone SPECT/CT.

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Easy Interpretation of Heterotopic

Ossification Demonstrated

on Bone SPECT/CT

Yin Lin, MD,* Wan Y. Lin, MD,*þ§ Chia H. Kao, MD,Þþ and Shih C. Tsai,

MD*§

Abstract: A 29-year-old male patient suffered from paraplegia 6 months after brain injury. Heterotopic ossification was diagnosed based on clinical characteristics such as decreased range of motion at the bilateral hips without infective signs. A planar bone scintigraphy using 99mTc-MDP showed

intensive radiotracer accumulation in the proximal portion of the bilateral femurs and the right acetabulum. The SPECT/CT images showed increased radiotracer accumulation in the adjacent soft tissues of the bilateral hips but not in the bone. The conservative treatment rather than surgical intervention was given according to the findings in bone SPECT/CT images.

Key Words: heterotopic ossification, bone scintigraphy, SPECT/CT (Clin Nucl Med 2014;39: 62Y63)

REFERENCES

1. Garland DE. A clinical perspective on common forms of acquired heterotopic ossification. Clin Orthop. 1991;263:13Y29.

2. Domanski M. Heterotopic ossification in paraplegia: a clinical study. J Bone Joint Surg Br. 1961;43-B:286Y299.

3. Wharton GW, Morgan TH. Ankylosis in the paralyzed patient. J Bone Joint Surg Am. 1970;52:105Y112.

4. Ragone DJ, Kellerman WC, Bonner FJ Jr. Heterotopic ossification masquerading as deep venous thrombosis in head-injured adult: complications of anticoagulation. Arch Phys Med Rehabil. 1986;67:339Y341.

5. Goldberg MA, Schumacher HR. Heterotopic ossification mimicking acute arthritis after neurologic catastrophes. Arch Intern Med. 1977;137:619Y621. 6. Ul Hassan F, Enayat M, Mohammed F, et al. Heterotrophic ossification in a patient suspected of having osteomyelitis additional value of SPECT/CT. Clin Nucl Med. 2012;37:170Y171.

7. Kjaersgaard-Andersen P, Ritter MA. Short-term treatment with nonsteroidal antiinflammatory medication to prevent heterotopic bone formation after total hip arthroplasty. Clin Orthop Relat Res. 1992;279:157Y162.

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the prevention of heterotopic ossification after total hip arthroplasty. J Bone Joint Surg Am. 1985;67:400Y403.

9. Coventry MB, Scanlon PW. The use of radiation to discourage ectopic bone: a nine-year study in surgery about the hip. J Bone Joint Surg Am. 1981;63: 201Y208.

10. Freed JH, Hahn H, Menter R, et al. The use of three-phase bone scan in the early diagnosis of heterotopic ossification (HO) and in the evaluation of Didronel therapy. Paraplegia. 1982;20:208Y216.

11. Tibone J, Sakimura I, Nickel VL, et al. Heterotopic ossification around the hip in spinal cord-injured patients: a long-term follow-up study. J Bone Joint Surg Am. 1978;60:769Y775.

I

NTERESTING

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MAGE

62 www.nuclearmed.com Clinical Nuclear Medicine

&

Volume 39, Number 1, January 2014

Received for publication July 12, 2012; revision accepted December 29, 2012.

From the *Department of Nuclear Medicine, Taichung Veterans General Hospital; †Department of Nuclear Medicine and PET Center, China Medical University Hospital; ‡Institute of Clinical Medicine Science and School of Medicine, China Medical University; and §Institute of Radiological Science, Central Taiwan University of Science and Technology, Taichung, Taiwan. Conflicts of interest and sources of funding: none declared.

Reprints: Shih-Chuan Tsai, MD, Department of Nuclear Medicine, Taichung Veterans General Hospital, 160 Taichung Harbor Road, Section 3, Taichung 407,

Taiwan. E-mail: [email protected].

Copyright * 2013 by Lippincott Williams & Wilkins ISSN: 0363-9762/14/3901Y0062

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