To whom it may concern,
As the Professor and Advisor of China Medical University and Hospital, I take great pride in writing this recommendation letter in support of Mr. Weng Ieong Tou, for his admission to the Undergraduate Research Project of NSC.
Mr. Tou showed extraordinary performances in both academics and research field as he had published numerous papers (1-7) during the first four years in CMU. He joined two laboratories for a short term rotation in the first academic year. After that he has joined my Lab at Department of Medical Research since 2011. He is devoted in the study of protein folding and drug discovery strategies of vascular triad: diuretic, stroke, hypertension and disordered protein from different views and he has published seven papers (affiliated as first author or co-first author) and more papers were still under review. At the moment, he is interested in many topics such as cancer (1) and pain regulation (2), but he is particularly interested in vascular renal disease and has been working on performing large-scale in vitro and in silico experiment, developing lead compounds and therapy for cardiovascular and renal diseases since 2012 (1, 3, 4). Therefore he has joined a large scale research project since 2012, in which he helped to develop selective agonist of NR2A/2B in molecular level for stroke (3). After that, he explored a new field and he has successfully developed the world first theory and protocol of designing drug for disordered protein (5) and proposed that the first evidences of the failure of drug design might be related to disordered protein (6) within one year. In the 2014, he went to Peking University for designing novel diuretic and has successfully developed novel hypothetical inhibition mechanism of novel urea transporter B Inhibitor (7). He has joined the Summer Research Program for Medical Students since 2014 and received the Outstanding Award from the Foundation of Health Science. In October 2014, he organized a small team with his classmates to initiate the Fusion Protein Project and now he is leading his team and trying to develop novel method for rational design of fusion protein and maximization of the function of fusion protein. At the same time, he is also running many multidisciplinary projects, one of them is to design diuretic by using Traditional Chinese Medicine to target urea transporter.
Apart from his academic excellence, he also revealed his talent in numerous extra-curriculum activities. He is the former player of the National Dragon Boat Team and National Single Scull Team of Macau China. He won numerous prizes in local aquatics competitions of Macau China. He demonstrated unparalleled enthusiasm, talent and ambition in the pursuit of medical knowledge, an unwavering motivation to learn, and the great empathy with patients suffering from various diseases.
Mr. Tou reveals his great talent in both research and clinical skill. I am confident that Mr. Tou will have the capacity to adapt, perform and achieve in this research program. He is perceptive and circumspect, and given his experiences in research and clinical, he will have no difficulty in working with the members of the staff and fellow doctors. It is with great pleasure to recommend him to the board of this research program.
Mr. Tou’ selected publication:
1. M. Li*, W. I. Tou* et al., Sci Rep 4, 5775 (2014). (Impact factor: 5.078)
2. W. I. Tou, C. Y. Chen, Drug Discov Today 19, 367 (Apr, 2014). (Impact factor:6.551) 3. C. Y. Chen#*, W. I. Tou*, Drug Discov Today 18, 910 (Oct, 2013). (Impact factor:6.551)
4. W. I. Tou, S. S. Chang, C. C. Lee, C. Y. Chen, Sci Rep 3, 844 (2013). (Impact factor: 5.078) 5. W. I. Tou, C. Y. Chen, J Biomol Struct Dyn 30, 299 (2012). (Impact factor: 4.98)
6. W. I. Tou, C. Y. Chen, PLoS One 7, e33728 (2012). (Impact factor: 3.73) 7. W. I. Tou et al., J Biomol Struct Dyn 32, 683 (2014). (Impact factor: 4.98) Thank you for your consideration.
Sincerely,
