題名:Epidemiologic shift in the prevalence of pertussis in Taiwan implications for pertussis vaccination
作者:吳和生
Lin YC; Yao SM; Yan JJ; Chen YY; Chiang CS; Wu HS; Li SY
貢獻者:醫學檢驗暨生物技術學系 上傳時間:2009-08-25T02:38:13Z
摘要:In Taiwan, routine pertussis immunization has been implemented for more than 40 years and a low incidence of pertussis was maintained until an 80-fold increase in cases occurred in 1992. The unexpected increase
emphasized the significance of pertussis. This study evaluated a total of 2452 reported cases of pertussis during 1993–2004 and surveillance data on incidence, age distribution and seasonality. The highest morbidity was in infants aged <1 year, and upward trends in the incidence of pertussis were significant for infants aged <1 year and adolescents aged 10–14 years. The highest mean number of cases was observed in August and upward trends were in colder months. This study indicates that the epidemiology of pertussis may have been changed by waning immunity in Taiwan. Increased surveillance
activities, especially in older age groups, and
additional booster doses of acellular pertussis vaccine for children aged 6–8 years and adolescents/young
adults aged 15–20 years are necessary to control and prevent pertussis.
