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Current Positions

Corporate Director Clinical Informatics Research & Development Chairman, Center for Information Technology Leadership

Partners Healthcare System, Inc.

Research Scientist, Decision Systems Group Assistant Professor of Medicine

Brigham & Women’s Hospital Harvard Medical School

[office] 93 Worcester Street Wellesley Gateway Wellesley, MA 02481 Phone: 781-416-8530 Fax: 413-653-2286 Mobile: 617-335-7098 Email: bmiddleton1@partners.org Assistant : Hope Thomas 781-416-8528

Education

Degree Year School, Location Subject B.A. 1979 University of Colorado,

Boulder Biochemistry, Molecular Biology, History 1979 University of East Anglia,

Norwich, England Biochemistry

M.P.H. 1981 Yale University Chronic Disease Epidemiology, Health Services Administration

M.D. 1985 SUNY-Buffalo Medicine

1985-1988 University of Connecticut John Dempsey Health Sciences Center

Internship and Residency in Categorical Internal Medicine

1988-

1991 Stanford University AHCPR Fellowship in Division of General Internal Medicine, Section on Medical

Informatics

Health Services Research, and Medical Informatics

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Employment History

2000-2001 Senior Vice President and Chief Medical Officer

MedicaLogic/Medscape, Inc. (dba Medscape, Inc.)

1997-2001 Associate Professor of Medical Informatics and Outcomes Research (Clinical) Biomedical Information and Communication Center (BICC)

Oregon Health Sciences University, Portland, OR

1995-2001 Attending Physician, St. Vincents Department of Medicine Faculty Practice, Providence Health System, Portland, OR

1998-2000 Senior Vice President for Clinical Informatics, MedicaLogic, Inc. 1995-8 Vice President for Clinical Informatics, MedicaLogic, Inc.

1994-5 Medical Director, Department of Information Management and Technology, Stanford Health Services.

1992-4 Medical Director Clinical Information Systems, Stanford University Hospital. 1991-5 Associate Director, Co-Founder, The Institute for Decision Systems Research

4894 El Camino Real, Suite 101, Los Altos, CA 94022.

1991 Acting Chief, Internal Medicine Clinic, Stanford University Medical Center, July

- December.

1991-5 Assistant Professor of Medicine (Clinical), Section on Medical Informatics Division of General Internal Medicine, Stanford University School of Medicine, Stanford, CA 94305.

1989-91 Physician Specialist, Department of Medicine, Stanford University Medical Center, Stanford, CA 94305.

1989-90 Voluntary Clinical Staff Attending, Palo Alto Veteran's Administration Hospital, Palo Alto, CA 94304.

1988-91 Agency for Health Care Policy and Research Fellow, Section on Medical

Informatics, Division of General Internal Medicine, Stanford University Medical Center.

1985-99 Intern and Resident in Internal Medicine, University of Connecticut Health Center and affiliated hospitals, Farmington and Hartford, CT.

1980 Commissioned Officer Student Training Externship Program (COSTEP),

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1975-76 Summer Student Research Intern, Harvard Medical School, Beth Israel Hospital, Boston, MA, Dr. Gary Huber, Preceptor.

Honors

2005 Partners Healthcare System, Inc. “Partners in Excellence Award” for Outstanding Contributions and Commitment to Excellence: Smart Forms and Quality Dashboards Team, December, 2005

2005 Recognition by Modern Physician as one of the Top 50 (#36) most powerful physician executives in 2005

2005 Elected Chairman, Healthcare Information Management and Systems Society (HIMSS), Board of Directors

2005 Nominated to serve on the MassPRO Quality Improvement Organization Board of Directors

2005 Nominated to serve on the HealthAlliant, Inc., Board of Directors

2005 Elected to Treasurer, American College of Medical Informatics (two year term) 2004 Elected to Chairman-Elect, Healthcare Information Management and Systems Society

Board of Directors (one year term)

2002 Elected to serve on Healthcare Information Management and Systems Society Board of Directors (three year term)

2002-5 Served on Foundation for eHealth Initiative Board of Directors

2002 Elected to Fellowship, Healthcare Information and Management Systems Society 2000 Elected to Fellowship, American College of Medical Informatics

2000 -01 Nominated to serve on Internet Healthcare Coalition eHealth Ethics Steering Group 1999-2000 Elected by CPRI Board of Directors as Chairperson, Executive Committee,

CPRI (Computer-based Patient Record Institute), Bethesda, MD

1997-9 Elected by CPRI Board of Directors as Director-at-Large, Executive Committee, CPRI (Computer-based Patient Record Institute), Bethesda, MD

1994 Elected to Fellowship, American College of Physicians

1988 Agency for Health Care Policy and Research (AHCPR) National Research Service Award for Fellowship at Stanford University School of Medicine, 1988-1991

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1985 Upjohn Achievement Award for Outstanding Research Ability, SUNY-Buffalo School of Medicine

1983 Glenn H. Leak Memorial Cancer Fellowship, American Cancer Society 1982 The Buffalo Foundation Student Research Grant

1975 University of Colorado Regent Scholarship

Clinical Practice, Research Interests, and Awards

LICENSURE

MA Physician’s License 213036 (active); OR Board of Medical Examiners, License 19771 (expired); CA Board of Physician Registration G063192 (expired); CT Medical Board 028275 (expired) Diplomate National Board of Medical Examiners Parts I-III, Certificate number 305052, 1987 Diplomate American Board of Internal Medicine, Certificate number 119956, 1989

RESEARCH INTERESTS

Design, implementation, and evaluation of integrated clinical information management systems, clinical decision support systems, quality management, population database analysis, patient healthcare

information access and disease management. POST-DOCTORAL RESEARCH FUNDING ACTIVE

1R01HS015169-01 (Middleton, PI) 09/30/04-09/29/07 25%

AHRQ $330,343

Evaluating Smart Forms and Quality Dashboards in an EHR Demonstrating the Value of Health Information Technology

1 R01 HS 13326-03 (Middleton, PI) 09/30/02-09/29/05 ext. 15%

AHRQ $354,670

Shared Online Health Records for Patient Safety and Care Patient Center Care – Customizing Care to Meet Patient’s Needs

1 UC1 HS155397-01 (Bates, PI) 09/30/04-09/29/07 5%

AHRQ $468,614

Statewide Implementation of Electronic Health Records

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1 R01 HS 015226-01 (Gandhi, PI) 09/03/04-08/31/07 5%

AHRQ $288,913

Improving Safety and Quality with Outpatient Order Entry Demonstrating the Value of Health Information Technology

Center for IT Leadership (Walker J, PI) 9/30/2004-10/1/2009 15% AHRQ $1,010,000

The National Healthcare Information Technology Resource Center (HITRC). PRIOR AWARDS

2004 Center for IT Leadership (Middleton, PI). The value of information technology for healthcare information exchange and interoperability. EHealth Foundation – Connecting Communities for Better Health $ 75,000

2003 Center for IT Leadership (Middleton, PI) The Value of Healthcare Information Technology in Chronic Disease Management. Robert Wood Johnson Foundation $297,504

2003 Center for IT Leadership (Middleton, PI). Assessing the Value of IT for Healthcare

Information Exchange and Interoperability. eHealthInitiative – Connecting Communities for Better Health $63,750

2003 Tablet PC Research (Middleton, PI), Clinical Informatics R&D, Partners Healthcare., Microsoft Corporation $40,000

2003 The Value of Ambulatory CPOE in California. (Middleton, PI) Center for Information Technology Leadership, Boston, MA, California Health Care Foundation (CHCF) $65,000. 2001 Planning a Center for Knowledge-based Practices. US Army Medical Research Acquisition Activity. (Greenes, PI), one year support, $181,000. Brigham & Women’s Hospital.

1994 CalREN (California Research and Education Network - Pacific Bell Trust) support for

BACHEN: Bay Area Community Health and Education Network. 24 months for broadband network services. (Middleton, PI) Stanford.

1994 ARPA (Advanced Research Projects Agency) Technology Reinvestment Program support for NAMCIC: National Academic Medical Center Information Collaborative. (Middleton, PI) Stanford. 1992 NSF Grant Project IRI-9120330. Practical Decision Analytic Techniques in Large Belief Networks. 3 years support, $625,000. Senior Research Scientist, The Institute for Decision Systems Research, Palo Alto, CA.

1988 Agency for Health Care Policy and Research (AHCPR) National Research Service Award (NRSA), 1988-1991, for Fellowship in the Division of General Internal Medicine, Stanford University School of Medicine.

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Professional Activities

2006-7 Member, American Health Information Community (AHIC; DHHS Secretary Michael Leavitt, Chair) Breakthrough Workgroup on Electronic Health Records

2003-6 Member, Healthcare Information and Management Systems Society (HIMSS) Board of Directors

2002-3 Member, Data Standards Work Group, Markle Foundation Connecting for Health, e-Health Initiative

2002-3 Member, Physician Advisory Board, Express Scripts, Inc.

2002-3 Member, Business Strategy Task Force, American Medical Informatics Association 2002 - Chair, Clinical Systems Strategy Committee, Partners Healthcare System, Inc. 2002-3 Member, Brigham & Women’s Hospital Clinical Council, and Ambulatory Care

Sub-committee

2001- Referee, Journal of the American Medical Informatics Association

2000- Member, American College of Medical Informatics (ACMI), Scientific Affairs Committee.

2000-2001 Member, American Medical Informatics Association (AMIA) Membership Committee. 1997-9 Member, American Medical Informatics Association (AMIA) Professional Education

Committee.

1997-9 Member, Healthcare Information Management and Systems Society (HIMSS) Professional Development Committee.

1997-9 Member, Healthcare Information Management and Systems Society (HIMSS) Clinical Advisory Council to the HIMSS Board of Directors.

1997- Referee, Evidence Based Medicine

1997-9 Director-at-Large, Executive Committee, Computer-based Patient Record Institute (CPRI), Schaumberg, IL.

1997 Expert Advisor - NCQA Committee on Performance Measurement: "A Road Map for Information Systems: Evolving Systems to Support Performance Measurement." 1996 Consultant - External Reviewer for the John A. Hartford Foundation grant program. 1995 - Member, Scientific Board of Advisors, Multimedia Medical Systems.

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1995-2001 Computer-based Patient Record Institute (CPRI) Board of Directors.

1994-5 Alton Ochsner Medical Foundation/Sandia National Laboratory Contract #AN-6271 "The Role of Technology in Reducing Health Care Costs", Dr. Richard Re, PI.

1994-5 Member, National Library of Medicine Integrated Advanced Information Management System (IAIMS) grant program review panel.

1994-5 Secretary/Treasurer, American Telemedicine Association.

1994 Agency for Health Care Policy and Research, and National Library of Medicine (AHCPR/NLM) RFA LM-94-002 "Applied Research Relevant to an Electronic Medical Record", Member Special Study Section.

1994 Chair, Stanford Clinical Data Repository Steering Committee. 1994 Chair, Stanford Clinical Data Repository Focus Group Committee. 1994 Member, Stanford University Hospital Clinical Advisory Team. 1994 Consultant to Andersen Consulting, Cambridge, MA.

1994 Consultant to Cornerstone Research, Menlo Park, CA.

1993-5 Member, Stanford University Hospital Medical Records Reengineering Project Steering Committee.

1993-5 Member, Stanford University Hospital Critical Care Information System Steering Committee.

1993 Consultant to New Enterprise Associates, San Francisco, CA.

1993-4 Member, Stanford University Hospital Laboratory Information System Steering Committee.

1993-5 Member, Stanford University Medical Center Lane Library Steering Committee. 1992-5 Small Business Innovation Research (SBIR) Grant Program Technical Review Panel

Member, Phases I and II; Agency for Health Care Policy and Research Topic 005 - Electronic Patient Data Systems.

1992-5 Member, Stanford University Hospital Information Systems Action Team. 1992-5 Member, Stanford University Medical Center Information Systems Committee

(formerly Medical Center Information Systems Planning Committee).

1992-5 Member, CAMIS (Center for Advanced Medical Informatics at Stanford) Executive Committee, Stanford University School of Medicine, ex officio.

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1992-4 Member, Systems Evaluation Work Group, Computer-based Patient Record Institute (CPRI).

1992-3 Member, Requirements Advisory Board Healthcare Information Systems Working Group, Microelectronics and Microcomputer Technology Corporation (MCC). 1992 Referee, Sixteenth Annual Symposium on Computer Applications in Medical

Care (SCAMC).

1991-2 Consultant to Knowledge Data Systems, Inc., Larkspur, CA, Medical logic development for expert database system.

1991-2 Member, Division of General Internal Medicine Executive Committee, Stanford University School of Medicine, July-December.

1991- Referee, Computers and Biomedical Research.

1991- Referee, Computer Methods and Programs in Biomedicine.

1991-2 Referee, Fifteenth Annual Meeting of the Society for Medical Decision Making. 1990- Referee, Journal of the American Medical Association.

1989-90 Consultant to Lexical Technology, Inc., Alameda, CA, Medical Editor Unified Medical Language System Metathesaurus.

1989 -91 Stanford Medical School Internal Medicine House staff Mentor. 1988 University of California at San Francisco, School of Medicine Clinical

Epidemiology Program, Research Methods Workshop. 1984-8 Referee, Nutrition and Cancer.

Other Professional Memberships

1999- Member, American College of Physician Executives (ACPE)

1991- Member, Healthcare Information and Management Systems Society (HIMSS),

(Fellow 2002; Board of Directors 2003-2007, Chair-Elect 2004-2005, Chairman 2005-6) 1990- Member, Society for Medical Decision Making (SMDM)

1989- Member, American Medical Informatics Association (Fellow, 2000; elected Treasurer 2005)

1988- Member, American College of Physicians (Fellow 1994) 1987- Member, Society for General Internal Medicine (SGIM)

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Invited Presentations

KEYNOTE ADDRESSES

2006

Health Information Technology Symposium at the Massachusetts Institute of Technology (HIT Symposium at MIT), “The Need for a Third Hand in Stimulating the US HIT Market”, Boston, MA, July 17.

CHIMA/CHITA’06 (Chinese National Healthcare Information Technology Associations): “Progress toward the NHIN in the USA”, Xi’an, China, May 27.

Post Approval Summit at Harvard: “The Role of Healthcare Information Technology in Post-award Pharmacovigilence”, Boston, MA, May 8

Harvard Medical School Continuing Medical Education Course Patient-centered Computing and eHealth – State of the Field (Course Co-Director), “The Value of Healthcare Information Technology”, Boston, MA, April 29.

National Managed Health Care Congress (NMHCC): “Taking the Necessary Steps to Achieve Clinical and Financial Transparency in America’s Healthcare System”, Washington, D.C., April 26.

National Managed Health Care Congress (NMHCC): “Identifying and Communicating the Benefit of Electronic Health Records for Payers, Providers, and Consumers”, Washington, D.C., April 25. Asia-Pacific HealthCare Information Technology Forum: “US NHIN: Perspectives from the Center for IT Leadership and Partners Healthcare System”, Beijing, China, Feb. 27.

Healthcare Information Management and Systems Society Annual Healthcare Conference and Exhibition, Opening Ceremony Keynote Address: “HIT and the Hippocratic Oath”, San Diego, CA, Feb. 13.

Eclipsys Annual Executive Forum, “Improving America's Healthcare System by Investing in Healthcare Information Technology”, Dana Point, CA, Jan. 18.

2005

Claremont Graduate University School of Information Sciences and Technology Symposium on Personal Health Records: “The Many Faces of Person-centric Electronic Health Systems”, Claremont, CA, Dec. 3

American Medical Informatics Association Annual Symposium Semi-Plenary: “Realizing the Financial Benefits of Electronic Health Records: What Do the Data Show?”, Washington, D.C., October 25.

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International Standards Organization Technical Committee 215 (ISO TC-215) Global Healthcare Information Technology Summit – Rapporteur “The Need for Global Informatics Standards Harmonization”, Hamamatsu City, Japan, September 20.

Pennsylvania Medical Society eHealth Summit Keynote: “The Value of Healthcare Information Technology in Clinical Practice”, Harrisburg, July 26.

US Senate Centrists Caucus: “The Value of Healthcare Information Technology”, Washington, D.C., July 12.

Colorado Medical Society Annual Meeting Keynote Address: “The Value of Healthcare Information Technology in Clinical Practice”, Denver, June 24.

Selecting Expert Rules for Inclusion in Computerized Physician Order Entry Systems: National Consensus Development Conference: “Knowledge Engineering for HIT: The Need for a National Clinical Knowledge Repository”, San Francisco, June 22.

American Medical Association Organized Medical Staff Section Annual Assembly Keynote Addres (AMA-OMSS): “The Challenge to Achieve Electronic Connectivity in Healthcare”, Chicago, June 18. Kryptiq Corporation Annual Connectivity Summit: “The Financial Case for Interoperability”,

Portland, May 19.

ASTHO (Association of State and Territorial Health Officials) – PHIN (Public Health Information Network) Annual Conference: “Value of HIT to Public Health”, Atlanta, May 10.

University of Medicine and Dentistry of New Jersey (UMDNJ) – Robert Wood Johnson Medical School, Informatics Institute IAIMS Clinical Informatics Symposium: “EHR – State of the Art”, Piscataway, May 3.

American Medical Informatics Association (AMIA) 2005 Spring Congress: “The Value of ACPOE”, Boston, Apr 11.

CIMIT Research Forum, Massachusetts General Hospital: “Information Technology in Ambulatory Clinical Practice and Disease Management”, Boston, Mar 15.

University of Pittsburgh Medical Center: “ The Value of Healthcare Information Technologhy”, Pittsburgh, Mar 1.

World Healthcare Information Technology Conference: “Disruptive Technologies: Building the Case for Healthcare IT Investment”. Washington, D.C., Feb 1.

2004

California Health Care Foundation HealthCare Information Technology Summit: “Challenges to EMR/Clinical IT Systems Acquisition”, San Francisco, Nov. 18.

Cedars-Sinai Medical Informatics Grand Rounds: “Keeping Clinical Systems Smart: Knowledge Management for Effective Clinical Decision Support”, Oct. 21.

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HealthCare Information Technology Summit: “The Value of Healthcare Information Technology”, Oct. 20.

eHealth Initiative – Connecting Communities for Better Health: “The Value of EHR and Healthcare Information Exchange”, June 25.

Virginians Improving Patient Safety and Care Leadership Conference: “Technological Realities When Designing for Quality”, May 26.

Workgroup on Electronic Data Interchange (WEDI): “The Value of IT and EHR: Making the Case”. May 21

A View from the Top, HIMSS: “The Value of Healthcare Information Exchange and Interoperability”. Orlando, FL., Feb. 23.

2003

MIC2003: “US Perspectives on Clinical Informatics: The Experience at Partners Healthcare”. Rotterdam, The Netherlands, Nov. 21.

IMIA Primary Care Informatics Symposium: “Primary Care Informatics Research at Partners Healthcare”. Washington, D.C., Nov. 9.

Virginia Health Quality Center Annual Symposium: “Deriving Value from IT: The Quality Connection”. Pentagon City, VA. Oct. 4.

Muller Symposium at University of Chicago Hospitals & Health System: “Clinical Computing”. Chicago, IL. June 9.

2002

GE Medical Systems, MedicaLogic Users’ Group Forum: “Defining Quality and Value in HealthCare: What can Medical Informatics Do?”. St. Louis, MO, May 8.

Children’s Hospital Boston Biomedical Informatics Grand Rounds: “Patient Computing in Partners HealthCare System.” Boston, MA, February 25.

2001

MedicaLogic/Medscape Users’ Group Forum, Invited Keynote Address: “E-Health and Disease Management, Where is the world going in the 21st Century?” Houston, TX, November 17.

ACMI (American College of Medical Informatics) Annual Debate: “Does national regulatory mandate for provider order entry, to take effect by the end of 2005, portend greater benefit than risk for health care delivery? -- Affirmative.” American Medical Informatics Association Annual Symposium,

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2000

California Healthcare Information Association/Healthcare Information Management and Systems Society -- Keynote Address: Online Health Records. Newport Beach, CA, September 7.

AMA/Intel Internet in Healthcare, Invited Keynote Address: The Internet in Healthcare: Implications for Physicians and their Patients. Miami, FL, Jan. 29.

1999

Oregon Health Sciences University web@ohsu conference, Keynote Address: Internet Health Records: Implications for Healthcare Quality, Service, and Satisfaction. Portland, OR, Oct. 15.

1998

Electronic Patient Record in Medical Practice (EPRiMP), Joint Conference of IMIA WG 17, EMD 98, and EUROREC 98 Invited Keynote Address: State of the Market for EMR in the USA. Rotterdam, The Netherlands, Oct. 6-11.

1993

IBM Information Systems Conference: Keynote Address: Clinical Information Systems - We're All in this Together. Fresno, CA, Oct. 21.

SELECTED OTHER INVITED PRESENTATIONS 2006

American College of Medical Informatics Annual Symposium: “Knowledge Management”, Phoenix, AZ, Feb 20.

2005

Source Media 6th Annual Healthcare Bond Buyer’s Conference: “Information Investments: Making

Them Pay”, Boston, MA, Nov. 14, 2005

World Healthcare Innovations and Technology Congress: “Quality Perspectives: Impact of Healthcare IT”, Washington, D.C., November 10, 2005

World Healthcare Innovations and Technology Congress: “IT and Patient Interaction Case Studies: The Partners Patient Gateway”, Washington, D.C., November 10, 2005

US New Democrats Coalition Caucus: “The Value of Heatlhcare Information Exchange and Interoperability”, Washington, D.C., July 25.

2002

American Medical Directors of Information Systems (AMDIS) Physician-Computer Connection: “Computer-based Provider Order Entry at Partners HealthCare”. Ojai, CA, July 22.

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Toward and Electronic Patient Record (TEPR) Annual Meeting: “Best Practices for Clinical Transformation: Partners HealthCare”. Seattle, WA. May 13.

Healthcare Information Management and Systems Society Annual Meeting: “Clinical Careers--Making The Leap From Patient Care To Informatics.” Atlanta, GA, January 29.

2001

The Clinic Club Fall Conference: “E-Health – Connecting with Patients and Consumers.” Bemidji, MN, September 9.

California Health Information Executives Forum: New Paradigm for Provider-Patient Disease Management: The Shared Digital Health Record. Long Beach, CA, Jan. 19.

2000

National Committee on Vital and Heath Statistics: Invited Testimony on the Interim Reports Toward a National Health Information Infrastructure and Shaping a Vision for 21st Century Health Statistics. San Francisco, CA, October 30.

Harvard/UCSF Partnerships for Quality Education: Technology As a Wild Card in Transformative Change for Healthcare. La Jolla, CA, October 21.

Merck Pharmaceuticals Managed Care Medical Directors Meeting: A New Paradigm in Shared Provider-Patient Disease Management. Santa Fe, NM, October 20.

Healthcare Marketing and Communications Council: Medical Ethics - Promises and Perils of the Internet in Healthcare. Hoffman-La Roche, Nutley, NJ, October 18.

l'accèss au dossier medical (UNPHC): Patient Access to Online Health Records: The Medscape Experience. Paris, France, October 12.

Internet Healthcare Coalition Annual Meeting: Consumer Perceptions of Online EMR: Results from Pilot Study. Las Vegas, NV, October 3.

Future of Healthcare Technology Annual Meeting: Building Electronic Trust with Self Help Tools, and Future of Medical Decision Support and Knowledge Management. MIT Media Lab, Boston, MA, September 26.

The eHealth Colloquium - Harvard University: Clinical Implications of the Healthcare Internet. Boston, MA, August 22.

Bureau of Primary Health Care, HRSA, DHHS -- Quality Management Network Meeting: Current Technology in Healthcare. Vail, CO, July 28.

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International Patient Safety Forum: Clinical Decision Support: It's Not Just for Your Doctor Anymore. Dallas, TX, June 29.

Association for Health Services Research Annual Meeting: Health Services Research and Informatics: Data, Data Everywhere - Nary a Byte to Study. Los Angeles, CA, June 26.

Stanford University School of Medicine, Section on Medical Informatics, Medical Informatics Short-course: Introduction to Electronic Health Records. Stanford, CA, June 13 and August 14.

American Medical Informatics Association Spring Congress: Practice Profiling: Real Time Clinical Benchmarking at the Point of Care. Boston, MA, May 24.

TEPR2000 (Toward and Electronic Patient Record): Consumer Impressions Using Internet Health Records. San Francisco, CA, May 11.

TEPR2000 (Toward and Electronic Patient Record), The Internet Health Record. San Francisco, CA, May 9.

Healthcare Information Management and Systems Society (HIMSS) Annual Meeting: Journal of

Healthcare Information Management Editor's Panel - Clinical Decision Support. Dallas, TX, April 11. Healthcare Information Management and Systems Society (HIMSS) Annual Meeting: CEO/CIO Roundtable participant. Dallas, TX, April 10.

Institute of the Future Invited Participant - Envisioning eHealthcare Futures. San Francisco, CA, April 6.

Drug Information Association: Online Health Records for Office-based Practice. Duke University, Durham, NC, April 4.

Federal Bureau of Primary Care, Health Research Services Administration: Online Health Records for the Federal Bureau of Primary Care. Washington, DC, March 28.

AMA Leadership Conference Invited Address: The Internet in Healthcare: Implications for Physicians and their Patients. Miami, FL, March 25.

American Association of Allergy, Asthma, and Immunology (AAAAI) Invited Presentation: Medical Informatics and Technology: Where is the Doctor? San Diego, CA, March 6.

Oregon State University, Invited Lecture: Healthcare Information Systems and the Internet: 4th Generation Clinical Computing. Corvallis, OR, Feb. 26.

Agency for Healthcare Research and Quality (AHRQ) invitational meeting: Developing the AHRQ Research Agenda. Washington, DC, Feb. 17.

Privacy, Security, and Confidentiality of Medical Records 2000: HIPAA and Internet Health Records. University of Utah, Salt Lake City, Jan. 24.

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1999

Healthcare Open Systems Trials (HOST) Annual Meeting: Internet Health Records. National Institute for Standards and Technology, Gaithersburg, MD, Dec. 15

Pri-Med East Conference: What's important in an EMR system? Harvard Medical School, Boston, MA, Dec. 12.

Radiological Society of North America: Scientific Session - Integrating the Healthcare Enterprise, Consumer-focus, Outreach, Patient-centered Care. Chicago, IL, Dec. 2.

Yale University School of Medicine Department of Medical Informatics Seminar: Internet-based Healthcare Technologies to support Clinical Practice: Research Issues. New Haven, CT, Nov. 22. American Medical Informatics Association Annual Symposium: Knowledge Engineering for the EMR- From Vocabulary Term, to Encounter, to Report. Washington, D.C., Nov. 6.

American Association of Health Plans Annual Convention: Internet-based Healthcare Services for Physicians. Palm Springs, CA, Oct. 28.

Buffalo Allergy Society First Elliott Middleton, Jr., MD Memorial Lectureship: The Internet in Medicine. Buffalo, NY, Oct. 21.

National Committee on Vital and Health Statistics, Workgroup on Computer-based Patient Records: Data Standards. Washington, D.C., Oct. 14.

MISA/MISPA Conference: EMR and Efficient Management of Outpatient Medical Practice. New York, NY, Oct. 11.

The Clinic Club, Panel Presentation: Overcoming Challenges in Implementing EMR. New Orleans, LA, Oct. 9.

Institute of Medicine, National Academy of Sciences Roundtable: Information Technology and the Quality of Care. Washington, D.C., Sep. 29.

Memorial Care Technology Conference: Visualize the Future. Memorial Care Health System. Long Beach, CA, Sep. 18.

American Medical Association / Intel Internet in Health Day: The Internet and Physicians. Austin, TX, Sep. 17.

Provider-Patient Relationships and the Hospitalist Movement, Annual Meeting of the National Association of Inpatient Physicians: Information Linkages Between Inpatient and Outpatient Physicians. San Francisco, CA, Sep. 11.

The Academic Medicine and Managed Care Forum Panel Presentation: Methods for the Madness: Critical Factors for Deriving Value from Electronic Health Records. Washington, D.C., Jun. 18.

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Toward an Electronic Patient Record '99 (TEPR). Panel Coordinator and Presenter: Perspectives on Cost-Benefit for the EMR. Orlando, FL, May 4.

Toward an Electronic Patient Record '99 (TEPR): Linking the Patient and the Provider with the Internet and the EMR. Orlando, FL, May 3.

Toward an Electronic Patient Record '99 (TEPR): Status of the Marketplace for EMR. Orlando, FL, May 3.

Medical Group Management Association (MGMA) Cardiovascular/Thoracic Surgery & Assembly: Office Management with Electronic Medical Records. Orlando, FL, Apr. 19-20.

Healthcare Information and Management Systems Society Annual Conference Hot Topic Panel: Automated Clinical Guidelines. Atlanta, GA, Feb. 24.

Healthcare Information and Management Systems Society Annual Conference panel presentation: The Role of the Computer-based Patient Record in the Healthcare Enterprise. Atlanta, GA, Feb. 22. American Medical Directors of Information Systems (AMDIS) Mini-conference at Healthcare

Information and Management Systems Society Annual Conference: The Electronic Automation of the Practice of Medicine. Atlanta, GA, Feb. 21.

1998

Expert testimony delivered to the Workgroup on Computer-based Patient Records of the National Committee on Vital and Health Statistics (NCVHS) regarding implications to Vendors of the Health Insurance Portability and Accountability Act (HIPAA) of 1996. Department of Health and Human Services, Washington, DC, Dec. 8-9.

American Medical Informatics Association - American Academy of Family Practice Mini-conference on Healthcare Informatics panel presentation: I Still Have a Dream (for Medical Informatics). Orlando, FL, Nov. 10-11.

Computer-based Patient Records Institute Fall Meeting panel presentation: What Makes a Good EMR Customer? Orlando, FL, Nov. 6.

Zeneca Pharmaceuticals Healthcare Symposium: Clinical Information Management and Decision Support for Physician Prescribing. West Palm Beach, FL, Oct. 23-24.

Microsoft Healthcare Users Group Windows on Healthcare IV Conference invited presentation: Critical Factors in Selecting and Implementing Electronic Patient Records. Orlando, FL, Oct. 11-14. Seventh Annual Physician-Computer Connection panel participant: Return on Investments for Ambulatory Practice Information Technology Investments. Ojai, CA, Jul. 22-24.

Medical Group Management Association (MGMA), Southern Chapter Annual Meeting invited

presentations: 1. Introduction to Electronic Medical Records for the Office Practice, 2. Deriving Value from the EMR. Orange Beach, AL, Jul. 12-15.

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Computer-based Patient Record Institute (CPRI) Seventh Annual Conference invited presentation: Deriving Value from the EMR. Washington, D.C., Jul. 9.

Stanford University School of Medicine, Section on Medical Informatics, faculty for Medical

Informatics Short-course: Introduction to Clinical Systems: Practical Issues in Knowledge Engineering for the EMR. Palo Alto, CA, Jun. 15-19.

National Association of Inpatient Physicians First Annual Conference: Information Systems and Data Management for Hospitalists. San Diego, CA, Apr. 1.

Healthcare Information Management Systems Society Annual Conference: Invited Hot Topic panel participant - Implementing CPR (Computer-based Record). Orlando, FL, Feb. 24.

Washington Medical Center Clinical Informatics Lecture Series - Kickoff Address: Introduction to Medical Informatics. Washington, D.C., Jan. 13.

1997

First Annual Managed Care Institute: Electronic Medical Records to Support Managed Care. Portland, OR, Nov. 7.

American Society of Nephrology Post-graduate Education Course: Practical Computing for Nephrologists: Computerized Medical Records for Office Practice. San Antonio, TX, Nov. 1. Shikany Primary Care Day: Introduction to Computer-based Patient Records for Ambulatory Care, and Directing Office Traffic with the EMR. Spokane, WA, Oct. 17.

Andover Working Group Fall Member Conference: Perspectives on Information Architecture and Solutions to Support the Physician. Boston, MA, Oct. 7.

Tenth National Conference on Clinical Computing in Patient Care, Harvard Medical School,

Department of Continuing Education, Center for Clinical Computing: Office Systems from a Vendor's Perspective. Boston, MA, Sep. 26.

Minnesota Health Data Institute: Standards for Ambulatory Practice Clinical Information. Minneapolis, MN, Sep. 19.

Oregon Health Sciences University Continuing Medical Education Program: Computer-based Patient Records for Office-based Practice: Implementing the Electronic Medical Record. Portland, OR, Sep. 6. Sixth Annual Physician-Computer Connection: Ambulatory Care Information Systems - Panel

Discussion. Ojai, CA, Jul. 16.

Ninth National Conference on Clinical Computing in Patient Care: Capturing the Clinical Encounter. Harvard Medical School, Department of Continuing Education, Center for Clinical Computing: A Marketplace perspective: Status of the electronic patient record. San Francisco, CA, Apr. 18.

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MediSpan Executive Visioning Consultant's Meeting, Panelist. Indianapolis, IN, Mar. 31.

The Sixth Annual National Managed Health Care Congress - WEST: Electronic Medical Records - Successfully Moving Toward Life-long Data Utilization. Palm Springs, CA, Jan. 31.

1996

The Sixth Annual Northeast Managed Health Care Congress: Essential Information System Requirements to Make the Longitudinal Patient Record a Reality. New York, NY, Nov. 14. Information Systems Caucus Western Conference of Prepaid Medical Service Plans: The Role of Clinical Information Software in the Integrated Delivery System. Park City, UT, Jul. 15.

American College of Physicians Annual Session: State of the Art Lecture: Diagnostic Decision Support. San Francisco, CA, Apr. 22.

Stanford University School of Medicine, Section on Medical Informatics Colloquium - Electronic Medical Records: What's real and what's not. Stanford, CA, May 12.

Oregon Health Sciences University Continuing Medical Education Program,: Computer-based Patient Records for Office-based Practice (same course offered again in Sept. 1996) Portland, OR, Jan. and Sep.

1995

Straight Talk on the Computerized Patient Record - CPR Buy-in Tips. National Report On Computers & Health/Med/Rec Automation And Management Report. Atlanta, GA, Dec. 5. American Medical Informatics Association Fall Symposium: Integrating Primary Care EMR with an Integrated Healthcare Delivery System. Washington, D.C., Nov.

Stanford Telemedicine. IEEE Northern California Chapter, Stanford University School of Medicine, Stanford, CA, Feb. 15.

1994

Computer-Assisted Diagnostic Decision Support: A Comparison of Three Commercially Available Programs: DxPlain, Iliad, and QMR. St. Peter's Community Hospital, Helena, MT, Oct. 21.

Healthcare Information Management Systems for the 1990's. Lewis and Clark Medical Society, Helena, MT, Oct. 20.

BACHEN: Bay Area Community Health and Education Network. Smart Valley, Inc. Workshop - Health Care and the Information Superhighway. Oct. 10. Also presented at the CalREN (California Research and Education Network) Launch Event, Oct. 12.

INTERNET and the Practicing Physician. Healthcare Financial Management Association. Berkeley, CA, Aug. 10.

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Healthcare Informatics - An Essential Technology for Healthcare Reform. Annual Meeting, New Enterprise Associates, Inc. San Francisco, CA, May 17.

Physician Order Entry. Society for Clinical Data Management Systems- 14th Annual Conference. New Orleans, LA, Mar. 16.

1993

Seventeenth Annual Symposium on Computer Applications in Medical Care (SCAMC): Functional Characteristics of the Computer-based Patient Record. Washington, D.C., Oct. 31.

Integrated Clinical Information Systems, Linking Process and Outcome with an Integrated Clinical Information Management System, Hamilton Civic Hospitals, McMaster University, Hamilton. Ontario, Canada, Jun. 7.

Healthcare Financial Management Association Third Annual Conference on Managed Care: Information Linkages Between Payors, Physicians, and Hospitals. San Francisco, CA, May 7.

American College of Physicians Annual Meeting: Computer-Based Diagnosis: Assessment of Current Systems. Musen MA, Detmer WM, Middleton B. Baltimore, MD, Apr 2.

Healthcare Information Management Systems Society: Linking Process and Outcome with an Integrated Clinical Information System. San Diego, CA, Mar 2.

Integrated Clinical Information Systems. Hewlett-Packard Labs, Palo Alto, CA, Jan. 19. 1992

Integrated Clinical Information Systems for the 1990's and Beyond. Mercy Healthcare Sacramento, Sacramento, CA, Oct. 12.

Information Systems and Clinical Decision Support. Presented to the Requirements Advisory Board Healthcare Information Systems Working Group, Microelectronics and Microcomputer Technology Corporation (MCC), at Sandia National Laboratory, Albuquerque, NM, Sept. 11.

1990

American Association for Artificial Intelligence Spring Symposium, Poster Presentation: A

Probabilistic Reformulation of the Quick Medical Reference System. Stanford University, Mar. 17. 1987

Member Connecticut Peace Delegation to Congress representing Connecticut Chapter of Physicians for Social Responsibility, Dec. 15.

1984

National Cancer Institute: Dietary Vitamin A and Cancer. US - Japan Symposium on Dietary Vitamin A and Carcinogenesis. Bethesda, MD, Feb. 22.

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Selected Bibliography

PEER-REVIEWED MANUSCRIPTS

1. Middleton B., Byers, T., Marshall, J., Graham, S. Dietary Vitamin A and Cancer: A Multisite Case-Control Study. Nutrition and Cancer 8:107-116; 1986.

2. Middleton, B. Computers in Medicine - An Overview. The Buffalo Physician 20:18-21, 1987. 3. Shwe, M., Middleton B., Heckerman, D., Henrion, M., Horvitz, E., Lehmann, H., and Cooper,

G. A probabilistic reformulation of the Quick Medical Reference system. KSL-90-11, March 1990. Proceedings of the AAAI Spring Symposium Series AI in Medicine, pp. 161-165, Stanford University, March 1990. Proceedings of the Fourteenth Annual Symposium on Computer Applications in Medical Care, pp. 790-794. Washington DC, November 1990. 4. Shwe, M., Middleton, B., Heckerman, D., Henrion, M., Horvitz, E., Lehmann, H., and Cooper,

G. Probabilistic diagnosis using a reformulation of the INTERNIST-1/QMR knowledge base. I: The probabilistic model and inference algorithms. KSL-90-09, February 1990. Methods of Information in Medicine 30:241-255, 1991.

5. Middleton, B., Shwe, M., Heckerman, D., Henrion, M., Horvitz, E., Lehmann, H., and Cooper, G. Probabilistic diagnosis using a reformulation of the INTERNIST-1/QMR knowledge base. II: Evaluation of diagnostic performance. Report KSL-90-68, October 1990. Methods of Information in Medicine 30:256-267, 1991. (Reprinted in the Yearbook of Medical Informatics 1992, pp. 311-322, Schattauer Pub., Stuttgart.)

6. Shiffman, S., Wu, A.W., Poon, A.D., Lane, C.D., Middleton, B., Miller, R.A., Masarie, F.E., Cooper, G.F., Shortliffe, E.H., and Fagan, L.M. A speech interface to a diagnostic system based on the INTERNIST-1 knowledge base. Report KSL-90-70, October 1990. Republished as Building a Speech Interface to a Medical Diagnostic System in IEEE Expert, pp. 41-50, February 1991.

7. Heckerman, D., Horvitz, E., and Middleton, B. An approximate non-myopic computation for value of information. Report KSL-91-15, March 1991. Also Proceedings of the Seventh Conference on Uncertainty in Artificial Intelligence, pp. 135-141. University of California at Los Angeles, 13-15 July 1991, and IEEE Transactions on Pattern Analysis and Machine Intelligence, volume 15 (1993), 3:292-298.

8. Lin, R., Lenert, L., Middleton, B., and Shiffman, S. A free-text processing system to capture physical findings: Canonical phrase identification system (CAPIS). Proceedings of the Fifteenth Annual Symposium on Computer Applications in Medical Care, pp. 168-172 . Washington, D.C., November 1991.

9. Shwe, M., Sujansky, W., and Middleton, B. Reuse of knowledge represented in the Arden syntax. Report KSL-92-19, March 1992. Proceedings of the Sixteenth Annual Symposium on Computer Applications in Medical Care, pp. 47-51, Baltimore MD, November 1992.

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10. Giuse NB, Giuse DA, Miller RA, Bankowitz RA, Janosky JE, Davidoff F, Hillner BE,

Hripcsak G, Lincoln MJ, Middleton B, Peden JG Jr. Evaluating the Reproducibility of Medical Knowledge Base Construction Methods of Information in Medicine 1993; 32: 137-45. 11. Guerrero BA, Rudd P, Bryant-Kosling C, Middleton, B. Antihypertensive Medication-Taking:

Investigation of a Simple Regimen. American Journal of Hypertension, 6:586-92, 1993. 12. Henry SB, Lenert L, Middleton B, Partridge R. Linking Process and Outcome with an

Integrated Clinical Information Management System Knowledge Systems Laboratory Report KSL-93-08; Proceedings of the 1993 Annual HIMSS Conference, pp. 57-81, 1993.

13. Pradhan M, Provan G, Middleton B, Henrion M. Knowledge Engineering for Large Belief Networks. In Proceedings of the Tenth Conference on Uncertainty in Artificial Intelligence, Seattle, Washington, 1994, Knowledge Systems Laboratory, Medical Computer Science, KSL-94-47, June 1994.

14. Middleton, B., Renner, K., Leavitt, M.K.. Lessons Learned in Deriving Benefit from Use of an Ambulatory Care Clinical Information Management System: Problems and Prospects. Journal of Healthcare Information Management, 11;4:97-112, 1997.

15. Middleton, B. "Introduction of EPR: Key Ingredients for Success or Failure." Proceedings of the EPR in Medical Practice, IMIA Workgroup 17 & Microsoft Healthcare User's Group - Europe (MS-HUGe) Meeting, Rotterdam, The Netherlands, October 7, 1998.

16. Middleton, B., Anderson, J., Masarie, Jr., F.E., Fletcher, J., Leavitt, M.K. "Use of the WWW for Distributed Knowledge Engineering for an EMR: The KnowledgeBank Concept. Proceedings of the Fifteenth Annual Symposium on Computer Applications in Medical Care, pp. 126-130. Orlando, FL, Nov. 7-11, 1998.

17. Klink, S., Middleton, B., Stetson, N. "The Role of the Computer-based Patient Record in the Healthcare Enterprise." Proceedings of the 1999 Annual HIMSS Conference, February 1999, Orlando, FL.

18. Zdon, L., Middleton, B. Ambulatory Electronic Records Implementation Cost Benefit: An Enterprise Case Study. Healthcare Information Management and Systems Society, Vol. 4, 97-117, February 1999.

19. Middleton, B., Brackett, L. "Initial Consumer Impressions Using Online Health Records." Proceedings of TEPR 2000 (Toward an Electronic Patient Record), San Francisco, CA, May 11, 2000.

20. Ricciardi TN, Masarie FE, Landholt T, Middleton B. "Clinical Benchmarking for the Office Practitioner Enabled by the Online Health Record." Proceedings of the Seventeenth Annual Symposium on Computer Applications in Medical Care, Los Angeles, CA, Nov. 7-11, 2000. 21. Ricciardi TN, Masarie FE, Middleton B. "Clinical Benchmarking Enabled by the Digital Health

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22. Hunt J, Siemienczuk J, Middleton B. "Use of an Electronic Medical Record in Disease Management Programs: A Case Study in Hyperlipidemia." Medinfo:2001:(10), 825-829. 23. Logan, J.R., Gorman, P., Middleton, B. "Measuring the Quality of Medical Records: A Method

for Comparing Completeness and Correctness of Clinical Encounter Data." Proc AMIA Symp: 2001:408-412.

24. Middleton B. The future of medical computing. Stud Health Technol Inform. 2002;80:85-98. 25. Overhage JM, Middleton B, Miller RA, Zielstorff RD, Hersh WR. Does national regulatory

mandate of provider order entry portend greater benefit than risk for health care delivery? The 2001 ACMI debate. The American College of Medical Informatics. J Am Med Inform Assoc. 2002 May-Jun;9(3):199-208.

26. Parton C, Wang SJ, Middleton B. Knowledge management: evaluating the organizational requirements and culture for an emerging technology. Proc AMIA Symp. 2002;:597-601. 27. Hobbs J, Wald J, Jagannath YS, Kittler A, Pizziferri L, Volk LA, Middleton B, Bates DW.

Opportunities to enhance patient and physician e-mail contact. Int J Med Inf. 2003 Apr;70(1):1-9.

28. Wang SJ, Middleton B, Prosser LA, Bardon CG, Spurr CD, Carchidi PJ, Kittler AF, Goldszer RC, Fairchild DG, Sussman AJ, Kuperman GJ, Bates DW. A cost-benefit analysis of electronic medical records in primary care. Am J Med. 2003 Apr 1;114(5):397-403.

29. Bates DW, Kuperman GJ, Wang S, Gandhi T, Kittler A, Volk L, Spurr C, Khorasani R,

Tanasijevic M, Middleton B.

Ten commandments for effective clinical decision support:

making the practice of evidence-based medicine a reality.

J Am Med Inform Assoc.

2003 Nov-Dec;10(6):523-30. Epub 2003 Aug 04.

30. Kuperman GJ, Marston E, Paterno M, Rogala J, Plaks N, Hanson C, Blumenfeld B, Middleton B, Spurr CD, Kaushal R, Gandhi TK, Bates DW.

Creating an Enterprise-wide Allergy

Repository At Partners HealthCare System.

Proc AMIA Symp. 2003;:376-80.

31. Jha AK, Poon EG, Bates DW, Blumenthal D, Middleton B, Kuperman GJ, Kaushal R. Defining the Priorities and Challenges for the Adoption of Information Technology in HealthCare: Opinions from an Expert Panel. Proc AMIA Symp. 2003:881.

32. Hobbs J, Kittler A, Fox S, Middleton B, Bates DW. Communicating Health Information to an Alarmed Public Facing a Threat Such as a Bioterrorist Attack. J Health Commun. 2004;9(1):67-75.

33. Middleton B, Hammond WE, Brennan PF, Cooper GF. Accelerating US EHR Adoption: How To Get There From Here, Recommendations Based on the 2004 ACMI Retreat. J Am Med Inform Assoc. 2004 Oct 18; [Epub ahead of print]

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34. Wald JS, Middleton B, Bloom A, Walmsley D, Gleason M, Nelson E, Li Q, Epstein M, Volk L, Bates DW. A Patient-controlled Journal for an Electronic Medical Record: Issues and

Challenges. Medinfo. 2004;2004:1166-72.

35. Yasnoff WA, Humphreys BL, Overhage JM, Detmer DE, Brennan PF, Morris RW, Middleton B, Bates DW, Fanning JP. A consensus action agenda for achieving the national health

information infrastructure. J Am Med Inform Assoc. 2004 Jul-Aug;11(4):332-8. Epub 2004 Jun 07.

36. Onofrei M, Hunt J, Siemienczuk J, Touchette DR, Middleton B. A first step towards translating evidence into practice: heart failure in a community practice-based research network. Inform Prim Care. 2004;12(3):139-45.

37. Rose AF, Schnipper JL, Park ER, Poon EG, Li Q, Middleton B. Using qualitative studies to improve the usability of an EMR. J Biomed Inform. 2005 Feb;38(1):51-60.

38. Walker J, Pan E, Johnston D, Adler-Milstein J, Bates DW, Middleton B. The Value of

Healthcare Information Exchange and Interoperability. Hlth Aff (Millwood) 2005 Jan-Jun;Suppl Web Exclusives:W5-10-W5-18.

39. Kaushal R, Blumenthal D, Poon EG, Jha AK, Franz C, Middleton B, Glaser J, Kuperman G, Christino M, Fernandopulle R, Newhouse JP, Bates DW; Cost of National Health Information Network Working Group. The costs of a national health information network. Ann Intern Med. 2005 Aug 2;143(3):165-73.

40. Middleton B. Achieving U.S. health information technology adoption: the need for a third hand. Health Aff (Millwood). 2005 Sep-Oct;24(5):1269-72

41. Linder JA, Bates DW, Williams DH, Connolly MA, Middleton B. Acute Infections in Primary Care: Accuracy of Electronic Diagnoses and Electronic Antibiotic Prescribing. J Am Med Inform Assoc. 2005 Oct 12; [Epub ahead of print]

42. Middleton B; The value of health care information technology in clinical practice. Am J Med Qual. 2005 Sept/December, 20(6):8-12.

43. Middleton B; Achieving the Vision of EHR – Take the Long View. Frontiers of Hlth Svcs Mgmt. 2005; 22(2):37-43.

44. Poon EG, Jha AK, Christino M, Honour MM, Fernandopulle R, Middleton B, Newhouse J, Leape L, Bates DW, Blumenthal D, Kaushal R. Assessing the level of healthcare information technology adoption in the United States: a snapshot. BMC Med Inform Decis Mak. 2006 Jan 5;6:1.

45. Linder JA, Rose AF, Palchuk MB, Chang F, Schnipper JL, Chan JC, Middleton B. Decision support for acute problems: The role of the standardized patient in usability testing. J Biomed Inform. 2006 Jan 6; [Epub ahead of print]

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46. Kaushal R, Jha AK, Franz C, Glaser J, Shetty KD, Jaggi T, Middleton B, Kuperman GJ, Khorasani R, Tanasijevic M, Bates DW. “Return on Investment for a Computerized Physician Order Entry System”, J Am Med Inform Assoc. 2006 Feb 24; [Epub ahead of print].

THESES

1. Middleton, B. Independent Study: A Scanning Electron Microscopy Study of the Jensen Bleb. Dr. Keith Porter, Preceptor, University of Colorado Department of Molecular, Cellular, and Developmental Biology, 1978.

2. Middleton, B. Blood Plasma Utilization in Connecticut. Yale University School of Medicine, Department of Epidemiology and Public Health, Master of Public Health (M.P.H.) Thesis, 1981.

3. Middleton, B. The Quick Medical Reference - Decision Theoretic Project: Evaluation of Diagnostic Performance. Stanford University School of Medicine, Department of Medicine, Division of Health Research and Policy Master of Science (M. Sc.) Thesis, 1991.

BOOKS

1. Middleton, B. Clinical Decision Support Systems. John Wiley & Sons, 1999, New York; ISBN: 078794923X

2. Johnston J, Pan E, Walker JD, Bates DW, Middleton B. The Value of Computerized Provider Order Entry in Ambulatory Settings. Center for Information Technology Leadership, 2003, Boston, MA.

3. Pan E, Johnston D, Walker JD, Adler-Milstein J, Bates DW, Middleton B. The Value of Healthcare Information Exchange and Interoperability. Center for Information

Technology Leadership, 2004, Boston, MA. 2005. BOOK CHAPTERS

1. Gibson RF, Middleton, B. "Healthcare Information Systems To Support Continuous Process Improvement." In Clinical Practice Improvement: A New Technology for Developing Cost-Effective, Quality Health Care. Faulkner and Gray, 1994.

2. Middleton B, Detmer W, Musen MA. Diagnostic Decision Support. Chapter in American College of Physicians Guide to Computers in Medicine. American College of Physicians, 1995. 3. Middleton B., Janas, J. J. "Identifying and Understanding Business Processes.” In Electronic

Patient Records. Editor: Jerome Carter, MD. American College of Physicians-American Society of Internal Medicine (ACP-ASIM), 2000.

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4. Middleton B. "The Future of Medical Computing.” Chapter in The Future of Health Technology. IOS Press, Amsterdam. 2001.

5. Middleton B. “The Value of Electronic Health Records”. Chapter 4 in HealthePeople, Kolodner R, Demetriedes J. Eds.

6. Middleton B, Gandhi TK, Bates DW. “Patient Safety: The Role of Information Technology”. Chapter in Effective Management of Healthcare Information: Leadership Roles, Challenges, and Solutions. HIMSS (Healthcare Information Management and Systems Society)

Publications, Chicago, 2003.

7. Maviglia S, Kuperman G, Middleton B. “Hospital Information Systems”. Chapter in Hospital Medicine, Wachter R., Ed., 2005

8. Middleton B. “The Evolution of Information Technology in Healthcare”. Chapter in Medical Practice Transformation with Information Technology. HIMSS (Healthcare Information Management and Systems Society) Publications, Chicago, 2005.

ABSTRACTS AND LETTERS

1. Parad, R., Calihan, M., Pollack, G., Middleton, B., Sornberger C., Huber G. The Combined Effects of Alcohol and Marijuana or Tobacco on the Antibacterial Defenses of the Lung. Abstract in American Review of Respiratory Diseases 1976; 113; 73.

2. Middleton, B., Eggerter, S. Water Hardness and Cardiovascular Disease. Epidemiology Monitor 1981; 2:5-6.

3. Middleton, B., Kovach, J., Tovar, M. Cost-Effectiveness of a Medical Decision-Support System: A Pilot Study. Stanford University Knowledge Systems Laboratory Report KSL-91-45, 1991. Abstract in Proceedings of the American Federation for Clinical Research, pg. 605A, Spring 1991.

4. Edison S, Middleton, B. Patient Use of an H.I.S. E-Mail System. Abstract in Proceedings of the AMIA Spring Congress, San Francisco, CA, May 4-7, 1994.

5. Middleton, B. "Integrating Care Across Diverse Care Settings: the Role of the CPR for the Hospitalist." The Hospitalist, 1998; Vol 2, No. 3, pp. 3-6.

6. Middleton, B.. "HCFA E&M Code Requirements: A New Chore for Physicians." CPRI-Mail, April, 1998.

7. Metzger, J., Middleton, B. "Consumer Informatics and the CPR." CPRI-Mail, July, 1999. 8. Holleran K, Pappas J, Lou H, Rubalcaba P, Lee R, Clay S, Cutone J, Flammini S, Kuperman G,

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9. Pizziferri L, Kittler A, Volk LA, Hobbs J, Jagannath Y, Wald JS, Middleton B, Bates DW. Physicians' perceptions toward electronic communication with patients. Proc AMIA Symp. 2003;:972.

10. Poon EG, Wald J, Bates DW, Middleton B, Kuperman GJ, Gandhi TK. Supporting patient care beyond the clinical encounter: three informatics innovations from Partners Healthcare. Proc AMIA Symp. 2003:1072.

11. Poon EG, Kaushal R, Jha AK, Christino M, Honour MM, Fernandopulle R, Middleton B, Bates DW, Blumenthal D. Assessing the level of healthcare information technology adoption in the United States: a 2003 snapshot of the Boston and Denver markets. Medinfo.

2004;2004(CD):1815.

12. Li Q, Middleton B.

Get EMR to Work Smarter.

Medinfo. 2004;2004(CD):1718. 13. Boxwala AA, Denekamp Y, Greenes RA, Kuperman GJ, Middleton BL.

Survey and

evaluation of knowledge bases for clinical decision support.

Medinfo.

2004;2004(CD):1534. TEACHING & TUTORIALS

1. Middleton, B., Owens, D. K., Neese, R. Thirteenth Annual Society for Medical Decision Making Meeting, Precourse Coordinator and Instructor: Advanced Topics in Probabilistic Medical Reasoning Influence Diagrams and Belief Networks, Rochester, NY, Oct. 19-22, 1991. 2. Middleton, B., Owens, D. K., Neese, R., Schacter R. Fourteenth Annual Society for Medical

Decision Making Meeting, Pre-course Coordinator and Instructor: Advanced Topics in

Probabilistic Medical Reasoning: Influence Diagrams and Belief Networks, Portland, OR, Oct. 17-21, 1992.

3. Musen M.A., Detmer W. M., Middleton B. Computer-Based Diagnosis: Assessment of Current Systems. American College of Physicians Annual Meeting. Miami, FL, Apr. 22, 1995

4. Detmer W., Middleton, B., Musen, M. A.. American College of Physicians Annual Session, Workshop Tutorial: Diagnostic Decision Support. San Francisco, CA, Mar. 21, 1996. 5. Middleton, B., Masarie, F. E., O'Connor, J., Betts, C. Practical Issues in Knowledge

Engineering for the Electronic Medical Record: From Vocabulary Term to Encounter Form to Report. Tutorial: American Medical Informatics Association Fall Symposium (formerly

SCAMC), Nashville, TN., Oct. 26, 1997.

6. Middleton, B., Masarie, F.E., Landholt, T. American Medical Informatics Association Spring Congress: Tutorial T1 - Practical Knowledge Engineering for the EMR. Philadelphia, PA, May 27, 1998.

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7. Middleton, B., Masarie, F.E., Shein, D. American Medical Informatics Association Annual Symposium Tutorial: Practical Knowledge Engineering for the EMR: From Vocabulary Term, to Encounter Form, to Report. Orlando, FL, Nov. 8, 1998

8. Middleton, B. Electronic Patient Record in Medical Practice (EPRiMP), Joint Conference of IMIA WG 17, EMD 98, and EUROREC 98 Pre-course workshop: Introduction of the EPR. Rotterdam, The Netherlands, Oct. 6-11, 1998.

9. Middleton, B., Masarie, F., E. American Medical Informatics Association Spring Congress: Tutorial T1 - Practical Knowledge Engineering for the EMR. Philadelphia, PA, May 27, 1998 10. Middleton, B., Gibson, R. F., Chin, H. Toward and Electronic Patient Record Annual

Symposium: Tutorial MP06, Clinical Information Systems. San Antonio, TX, May 11, 1998 11. Middleton, B., Gibson, R. F., Chin, H. Toward an Electronic Patient Record '99 (TEPR):

Tutorial SP-4 Introduction to Clinical Systems. Orlando, FL, May 1, 1999

12. Middleton, B., Pan, E., Johnston, D., Walker, J. Modeling the Return on Investment of Ambulatory Computer-based Provider Order Entry. American Medical Informatics Association Fall Symposium (formerly SCAMC), Washington, D.C., Nov. 9, 2003

13. Pan, E., Johnston, D., Walker, J, Middleton, B. Deriving Value from Ambulatory CPOE. HIMSS Annual Symposium, Orlando, FL, Feb 22, 2004.

14. Bates, DW, Middleton, B. (Course Co-Director). Medical Informatics HSPH512, in the Harvard School of Public Health Preparation for Clinical Effectiveness Summer Program, 2003—Every Summer

MANUSCRIPTS IN PREPARATION

Reilly, C., Pizzifieri, L., Middleton, B. “Health Care Quality Performance Data: A Catalogue of Internet Sites”.

參考文獻

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