Apnea-hypopnea index in nonobese women with polycystic ovary syndrome
Hsiao-Ping Yang, Jiunn-Horng Kang, Hsiu-Yueh Su, Chii-Ruey Tzengb, Wei-Min Liu and Shih-Yi Huang
Yang HP;Kang JH;Su HY;Tzeng CR;Liu WM;Huang SY
Abstract
Objective
To assess the influence of polycystic ovary syndrome (PCOS) on respiratory events during sleep in nonobese Taiwanese women.
Method
Overnight polysomnography was recorded in 18 nonobese women with PCOS who had not received treatment (body mass index [BMI] 21.7 ± 0.57, age 29.1 ± 1.43 years) and in 10 age- and BMI-matched women without PCOS (BMI 20.9 ± 0.58, age 31.6 ± 3.87 years).
Results
The nonobese women with PCOS had a higher total apnea–hypopnea index (AHI) especially during the non-rapid eye movement stage (AHINREM) than the women who did not have PCOS. The women with PCOS had higher serum levels of
high-sensitivity C-reactive protein (hsCRP) and this was positively correlated with AHIREM. Total testosterone level was positively correlated with AHINREM, and androstenedione was negatively correlated with AHINREM.
Conclusion
PCOS was directly linked to increased obstructive respiratory events during sleep in nonobese women in Taiwan.
