Author(s): Tsai, HJ (Tsai, Hsin-Jen); Tsai, ACH (Tsai, Alan Chung-Hong)
Title: The association of plasma C-reactive protein levels with anthropometric and lipid parameters in elderly Taiwanese
Source: ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 17 (4): 651-656 2008 Language: English
Document Type: Article
Author Keywords: C-reactive protein; elderly; waist-to-hip ratio; high-density lipoprotein- cholesterol; anthropometric indices
KeyWords Plus: CARDIOVASCULAR RISK-FACTORS; VISCERAL ADIPOSE-TISSUE;
CORONARY-HEART-DISEASE; NECROSIS-FACTOR-ALPHA; TRIAL M-CHAT;
METABOLIC SYNDROME; INSULIN-RESISTANCE; BODY-FAT; HEALTH; WOMEN
Abstract: C-reactive protein (CRP), a plasma inflammation marker, has been known to play a role in the development of cardiovascular diseases. This study aims to evaluate the
association of CRP with anthropometric and plasma lipid parameters in elderly Taiwanese 65 years or older. Data from the Elderly Nutrition and Health Survey in Taiwan (1999-2000), a national probability sampling study conducted to gain an understanding of the dietary pattern, and nutritional and health status of elderly Taiwanese were analyzed. Results showed that in men, CRP was positively correlated with age and waist-to-hip ratio (WHR) (both p < 0.05) whereas in women, CRP was positively correlated with waist and WHR but negatively correlated with HDL-C (all p < 0.05). Linear regression analysis showed that log CRP was positively associated with WHR in both genders (p < 0.05) after adjusting for confounders. The correlation of CRP with WHR was stronger than that with both waist circumference and body mass index (BMI). Log CRP was inversely associated with HDL-C in women, but not men. The study suggests that among the anthropometric parameters examined, WHR is a stronger predictor for elevated CRP in elderly Taiwanese men and women. Whereas low HDL-C is a predictor among the plasma lipid parameters for elevated plasma CRP, at least in women.
Gender differences exist in the association of CRP with anthropometric and lipid parameters.
Addresses: [Tsai, Hsin-Jen] I Shou Univ, Dept Hlth Management, Kaohsiung 82445, Taiwan;
[Tsai, Alan Chung-Hong] Asia Univ, Grad Inst Healthcare Adm, Taichung, Taiwan Reprint Address: Tsai, HJ, I Shou Univ, Dept Hlth Management, 8 Yida Rd, Kaohsiung 82445, Taiwan.
E-mail Address: hsinjen@gmail.com Funding Acknowledgement:
Funding Agency Grant Number
Department of Health in Taiwan DOH-88-FS
DOH89-88shu717 DOH90-FS-5-4 DOH 91-FS-5-4 Institute of Biomedical Sciences of Academia Sinica
The Elderly Nutrition and Health Survey in Taiwan (1999-2000) (Elderly NAHSIT) was funded by the Department of Health in Taiwan (DOH-88-FS. DOH89-88shu717. DOH90-FS-5-4.
DOH 91-FS-5-4). This project was conducted by the Institute of Biomedical Sciences of Academia Sinica, supervised by Dr. Wen-Ham Pan, the Office of Nutrition Survey. The authors have no affiliation with any organization with a direct or indirect financial interest in the subject matter discussed in the manuscript.
Cited References: ALBERT MA, 2003, CIRCULATION, V108, P161, DOI 10.1161/01.CIR.0000080289.7216.CF.
ALBERT MA, 2006, CIRCULATION, V114, E67, DOI 10.1161/CIRCULATIONAHA.106.613570.
ARENA R, 2006, J CARDIOPULM REHABIL, V26, P323.
BARINASMITCHELL E, 2001, AM J EPIDEMIOL, V153, P1094.
BERMUDEZ EA, 2002, ARTERIOSCL THROM VAS, V22, P1668, DOI 10.1161/01.ATV.0000029781.31325.66.
BRUUNSGAARD H, 2000, CLIN EXP IMMUNOL, V121, P255.
CHAMBERS JC, 2001, CIRCULATION, V104, P145.
CUSHMAN M, 2005, CIRCULATION, V112, P25, DOI 10.1161/CIRCULATIONAHA.104.504159.
FROHLICH M, 2000, DIABETES CARE, V23, P1835.
HEINRICH PC, 1990, BIOCHEM J, V265, P621.
HOTAMISLIGIL GS, 1995, J CLIN INVEST, V95, P2409.
JACKSON AS, 2002, INT J OBESITY, V26, P789.
LAKOSKI SG, 2006, AM HEART J, V152, P593, DOI 10.1016/j.ahj.2006.02.015.
LEAR SA, 2003, METABOLISM, V52, P1542, DOI 10.1016/S0026-0495(03)00379-2.
LEAR SA, 2006, ETHNIC DIS, V16, P96.
LEAR SA, 2007, AM J CLIN NUTR, V86, P353.
LEE MS, 2005, ASIA PAC J CLIN NUTR, V14, P285.
LIBBY P, 2002, CIRCULATION, V105, P1135.
LIM S, 2005, DIABETES RES CLIN PR, V70, P126, DOI 10.1016/j.diabres.2005.02.020.
MENDALL MA, 1996, BRIT MED J, V312, P1061.
NAKANISHI N, 2005, CIRC J, V69, P386.
PAN WH, 2005, ASIA PAC J CLIN NUTR, V14, P203.
PARK YW, 2001, OBES RES, V9, P381.
PEARSON TA, 2003, CIRCULATION, V107, P499, DOI 10.1161/01.CIR.0000052939.59093.45.
PUROHIT A, 1995, J CLIN ENDOCR METAB, V80, P3052.
REXRODE KM, 2003, ANN EPIDEMIOL, V13, P674, DOI 10.1016/S1047-2797(03)00053-X.
RICHARDS C, 1995, HUMAN CYTOKINES THEI, P253.
ROHDE LEP, 1999, AM J CARDIOL, V84, P1018.
ROSS R, 1999, NEW ENGL J MED, V340, P115.
SAIJO Y, 2004, DIABETES OBES METAB, V6, P249.
STRANDBERG TE, 2000, ARTERIOSCL THROM VAS, V20, P1057.
TRACY RP, 1997, ARTERIOSCL THROM VAS, V17, P2167.
VISSER M, 1999, JAMA-J AM MED ASSOC, V282, P2131.
YEH WT, 2005, INT J OBESITY, V29, P818, DOI 10.1038/sj.ijo.0802975.
YEN ML, 2006, INT J CARDIOL, V110, P191, DOI 10.1016/j.ijcard.2005.07.034.
Cited Reference Count: 35 Times Cited: 0
Publisher: H E C PRESS, HEALTHY EATING CLUB PTY LTD
Publisher Address: EMERALD HILL CLINIC 157 CLARENDON ST, SOUTHBANK, VIC 3006, AUSTRALIA
ISSN: 0964-7058
29-char Source Abbrev.: ASIA PAC J CLIN NUTR ISO Source Abbrev.: Asia Pac. J. Clin. Nutr.
Source Item Page Count: 6
Subject Category: Nutrition & Dietetics ISI Document Delivery No.: 395JM
