β - carotene with or without cholesterol on lipid metabolism
Beta-Carotene Affects Lipid Metabolism in Rats Fed with or without Cholesterol
Abstract
The purpose of this study was to explore β - carotene with or without cholesterol on lipid Generation
Xie effects. To 40 Wistar strain male rats (weighing about 250g) were randomly divided into 4 groups
1% cholesterol and 0.2% β - carotene to give or not give, for 2 × 2factorial experiment
Design. The group were in the first 3 weeks and 6 weeks respectively slaughtered half of rats, analysis of serum and liver
Total cholesterol (TC), triglyceride (TG), vitamin A and β - carotene, Blood
Clear and the analysis of the high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C)
Concentration. The results showed that when dietary cholesterol, in the first 3 weeks the concentration of liver TC
Significantly higher (P = 0.0001), serum TC concentrations increased in the first 6 weeks (P = 0.0256), and to not
For β - carotene fed group. 3 weeks, compared with no cholesterol, bile
Steroid serum HDL-C concentrations were lower (P = 0.0003), and LDL-C showed no significant difference (
P> 0.05); 6 weeks, not given β - carotene fed group HDL-C concentration was still low, but
LDL-C concentrations increased significantly (P <0.05), for β - carotene fed group no such phenomenon
, And HDL-C concentrations increased significantly (P <0.05).
Cholesterol to the liver TG concentrations in the first 3 weeks
That is significantly higher when (P = 0.0001), Serum TG concentrations either in 3 or 6 weeks, all with no
Cholesterol was no significant difference (P> 0.05); β - Carotene 3 weeks the liver TG
Concentration decreased (P = 0.0112), In serum TG concentration (P = 0.0220), while in the first 6 weeks
And not to β - carotene was no significant difference (P> 0.05).
Feeding cholesterol in serum and liver
Decrease the concentration of vitamin A, feeding β - carotene is to increase the concentration of liver vitamin A, but not
Affect serum vitamin A concentration. Serum β - carotene concentrations decline due to the uptake of cholesterol, Liver β - carotene concentration was not cholesterol uptake.
English Abstract
