[PDF] Top 20 The anti-proliferation effect of YC-1 in human vascular endothelial cells.
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The anti-proliferation effect of YC-1 in human vascular endothelial cells.
... 本篇論文的主旨在研究一藥物 guanylyl cyclase activator－YC-1 對於人類臍 帶靜脈內皮細胞(human umbilical vein endothelial cell, HUVEC)在體外(in vitro)生長的影響，並且探討其可能的作用機制。我們使用的實驗材料為初代培 養之人類臍靜脈內皮細胞，並且其繼代培養次數皆維持在 7 ... See full document
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YC-1 inhibits proliferation of human vascular endothelial cells through a cyclic GMP-independent pathway
... Arrest of cell cycle in G0/G1 In order to examine further the actions of YC-1 on the cell cycle, the cells were switched to media with ... See full document
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YC-1 inhibits proliferation of human vascular endothelial cells through a cyclic GMP-independent pathway
... changes of cyclins and CDKs. In the YC-1-treated HUVEC, the formation of CDK2-p21 complex, but not CDK2-p27 complex, was increased and the assayable CDK2 kinase ... See full document
1
Inhibition of Human Vascular Endothelial Cells Proliferation by YC-1 Through a cyclic GMP-Independent Pathway.
... YC-1 at a range of concentrations (5-50 microM) inhibited DNA synthesis and decreased cell number in cultured HUVEC in a dose- and time-dependent manner.. YC-1 was not cytotoxic at th[r] ... See full document
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Inhibition of Human Vascular Endothelial Cells Proliferation by YC-1 Through a cyclic GMP-Independent Pathway.
... [3H]thymidine incorporation and flow cytometry analyses revealed that YC-1 treatment decreased DNA synthesis and arrested the cells at the G0/G phase of the cell cycle.. Western blot an[r] ... See full document
1
Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells
... Abstract The aim of this study was to examine the anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH), an analogue of antiepileptic drug phenytoin ... See full document
1
Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells.
... In conclusion, these data suggest that DPTH inhibits HUVEC proliferation by increasing the level of p21 protein, which in turn inhibits CDK2 and CDK4 kinase activities, and finally inter[r] ... See full document
2
Anti-proliferation effect of 5,5-diphenyl-2- thiohydantoin (DPTH) in human vascular endothelial cells.
... treatment of HUVEC with DPTH arrested the cell at the G0/ G1 phase of the cell ...that the protein level of p21 increased after DPTH ... See full document
1
Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells.
... Y;Liang YC;Lin SY;Sheu MT;and Lee WS Abstract The aim of this study was to examine the anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH), an analogue ... See full document
1
Anti-proliferation effect of 3-amino-2-imino-3, 4-dihydro-2H-1,3- benzothiazin-4-one (BJ-601) on human vascular endothelial cells: G0/G1 p21-associated cell cycle arrest.
... In conclusion, these data suggest that BJ-601 inhibits HDMVECs proliferation by increasing the level of p21 protein, which in turn inhibits CDK2 kinase activity, and finally causes retar[r] ... See full document
2
Anti-proliferation effect of 3-amino-2-imino-3,4-dihydro-2H-1,3-benzothiazin-4-one (BJ-601) on human vascular endothelial cells: G0/G1 p21-associated cell cycle arrest
... target of the tumor suppressor gene p53 [20,21]. Expres- sion of p53 in the cells can induce cell growth arrest through transcriptional activation of p21 ...treatment ... See full document
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Anti-proliferation effect of 3-amino-2-imino-3,4-dihydro-2H-1,3-benzothiazin-4-one (BJ-601) on human vascular endothelial cells: G0/G1 p21-associated cell cycle arrest
... In conclusion, these data suggest that BJ-601 inhibits HDMVECs proliferation by increasing the level of p21 protein, which in turn inhibits CDK2 kinase activity, and finally causes ret[r] ... See full document
1
Inhibition of hunam vascular endothelial cells proliferation by terbinafine
... at the stage of squalene ...7 The cream form and oral tablet of TB have been approved for clinical uses in the United States, 8 and the oral formulation has been on ... See full document
9
vascular endothelial cells.
... administration of the cell membrane permeable cGMP analogue, 8-bromo-cGMP, which mimi cs the cGMP effect, does not cause any retardation in endothelial cell proliferation ... See full document
2
Structure and anti-proliferation function of 5; 5-diphenyl-2-thiohydantoin (DPTH) derivatives in vascular endothelial cells.
... 1995). The events that are thought to be essential for angiogenesis include: local degradation of the basement membrane of the parent vessel, allowing protrusion of ... See full document
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Lysophosphatidic acid up-regulates vascular endothelial growth factor-C and lymphatic marker expressions in human endothelial cells
... expressions of the lymphatic markers, Prox-1, LYVE-1, and podoplanin, in human endothelial ...cells. In addition, LPA also enhanced endothelial cell ... See full document
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Far-Infrared Therapy Induces the Nuclear Translocation of PLZF Which Inhibits VEGF-Induced Proliferation in Human Umbilical Vein Endothelial Cells
... influence of a thermal effect on VEGF-induced proliferation differed from that of FIR A thermal effect of FIR on the cell culture system was also examined in this ... See full document
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Inhibition of the ERK Phosphorylation Plays a Role in Terbinafine-Induced P21 Upregulation and DNA Synthesis Inhibition in Human Vascular Endothelial Cells
... suppresses proliferation of cultured HUVEC by inhibiting DNA synthesis and arresting cell-cycle activity through up-regulation of ...p21. In the present study, we further investigate ... See full document
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Anti-proliferation Effect on Human Breast Cancer Cells via Inhibition of pRb Phosphorylation by Taiwanin E Isolated from Eleutherococcus trifoliatus
... medicines. In our current study, taiwanin E, which possesses strong cytotoxicity, was isolated from the branches of ...potent anti-proliferation activity on the growth of ... See full document
1
Protein kinase C mediates induced secretion of vascular endothelial growth factor by human glioma cells
... Co-regulation of VEGF secretion and cell proliferation by growth factors Axiomatically, PTK and PKC exert major roles in cell proliferation and ...differentiation. In this study, all ... See full document
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