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[PDF] Top 20 Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.

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Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.

... production in our previous study. However, the apoptosis-inducing activity of emodin has remained ...including emodin, physcion, and chrysophanol, emodin showed the most ... See full document

1

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species production.

... production in our previous study. However, the apoptosis-inducing activity of emodin has remained ...including emodin, physcion, and chrysophanol, emodin showed the most ... See full document

1

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by active oxygen species production

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by active oxygen species production

... at apoptosis-inducing concentrations causes rapid and transient induction of caspase 3/CPP32 activity, but not caspase 1 activity, according to cleavage of caspase ... See full document

2

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease

... the human leukemia cell line, ...on HL-60 cells, with wogonin and fisetin being the most-potent apoptotic inducers among ...effects of wogonin and fisetin were accompanied ... See full document

2

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease.

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease.

... the human leukemia cell line, ...on HL-60 cells, with wogonin and fisetin being the most-potent apoptotic inducers among ...effects of wogonin and fisetin were accompanied ... See full document

2

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease.

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca2+-dependent endonuclease.

... the human leukemia cell line, ...on HL-60 cells, with wogonin and fisetin being the most-potent apoptotic inducers among ...effects of wogonin and fisetin were accompanied ... See full document

2

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease

Wogonin and fisetin induce apoptosis in human promyeloleukemic cells, accompanied by a decrease of reactive oxygen species, and activation of caspase 3 and Ca(2+)-dependent endonuclease

... the human leukemia cell line, ...on HL-60 cells, with wogonin and fisetin being the most-potent apoptotic inducers among ...effects of wogonin and fisetin were accompanied ... See full document

2

Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.

Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.

... (SAR) of PGs with apoptosis induction is still ..., but not others, mark- edly reduced cell viability in HUVECs, and that both 15- deoxy-D 12,14 -PGJ 2 and PGD 2 treatment induced ... See full document

14

Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.

Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species.

... presence of prostaglandins (PGs) has been demonstrated in the processes of carcinogenesis and ...inflammation. In the present study, we found that 12-o-tetradecanoylphorbol 13-acetate (TPA) ... See full document

2

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

... LEUKEMIA HL-60 CELLS; OXIDATIVE STRESS; DEATH; MECHANISMS; ARREST; ANTHRAQUINONES; INVOLVEMENT; ACTIVATION; INDUCTION; ROOTS Abstract: Emodin was isolated from Rheum palmatum ...on ... See full document

3

Emodin Induces Apoptosis of Human Tongue Squqmous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

Emodin Induces Apoptosis of Human Tongue Squqmous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways

... 摘要: Emodin was isolated from Rheum palmatum ...on human cancer cell lines, however, the molecular mechanisms of emodin-mediated apoptosis in human tongue cancer ... See full document

1

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways.

Emodin Induces Apoptosis of Human Tongue Squamous Cancer SCC-4 Cells through Reactive Oxygen Species and Mitochondria-dependent Pathways.

... demonstrated emodin induced ROS and Ca 2+ production, but induced dysfunction of mitochondria in SCC-4 ...generation of ROS may contribute to mitochondrial damage and lead to ... See full document

9

Hydroxylation at c4’or c6 is essential for apoptosis- inducing activity of flavanone through activation of the caspase 3 cascade and production of reactive oxygen species.

Hydroxylation at c4’or c6 is essential for apoptosis- inducing activity of flavanone through activation of the caspase 3 cascade and production of reactive oxygen species.

... roles in the antioxidative activities of flavonoids; however, the importance of structurally related hydroxylation in their apoptosis-inducing activities is still ...undefined. ... See full document

2

Hydroxylation at c4’or c6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase 3 cascade and production of reactive oxygen species.

Hydroxylation at c4’or c6 is essential for apoptosis-inducing activity of flavanone through activation of the caspase 3 cascade and production of reactive oxygen species.

... roles in the antioxidative activities of flavonoids; however, the importance of structurally related hydroxylation in their apoptosis-inducing activities is still ...undefined. ... See full document

2

Mitochondrial-dependent,reactive oxygen species-independent apoptosis by myricetin: role of protein kinase C, cytochrome C and caspase cascade

Mitochondrial-dependent,reactive oxygen species-independent apoptosis by myricetin: role of protein kinase C, cytochrome C and caspase cascade

... cleavage of the caspase 9 protein was also observed in ME-treated cells, represented here as the appearance of p35 and p17 fragments by Western blot- ting; the release of ... See full document

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Mitochondrial-dependent,reactive oxygen species-independent apoptosis by myricetin: role of protein kinase C, cytochrome C and caspase cascade

Mitochondrial-dependent,reactive oxygen species-independent apoptosis by myricetin: role of protein kinase C, cytochrome C and caspase cascade

... viability of human leukemia HL-60 cells via apoptosis, characterized by the occurrence of DNA ladders and hypodiploid ...Results of Western blotting and ... See full document

2

Mitochondrial-dependent, reactive oxygen species-independent apoptosis by myricetin: roles of protein kinase C, cytochrome c, and caspase cascade

Mitochondrial-dependent, reactive oxygen species-independent apoptosis by myricetin: roles of protein kinase C, cytochrome c, and caspase cascade

... Abrogation of mitochondrial permeability and induction of reactive oxygen species (ROS) production have been observed in chemical-induced apoptosis; however, the ... See full document

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Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and Nitric Oxide (NO) in human osteogenic

Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and Nitric Oxide (NO) in human osteogenic

... then cells were exposed to BITC and PEITC for examining the levels of ...difference in BITC or PEITC exposure ...induced apoptosis in U-2 OS cells may be through other different ... See full document

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Differential Apoptosis-Inducing Effect of Quercetin and its Glycosides in Human Promyeloleukemic HL-60 Cells by Alternative activation of Caspase 3 Cascade

Differential Apoptosis-Inducing Effect of Quercetin and its Glycosides in Human Promyeloleukemic HL-60 Cells by Alternative activation of Caspase 3 Cascade

... effect of glycosylation on their biological functions is still undefined. In the present study, the apoptosis-inducing activities of three structure-related flavonoids including aglycone ... See full document

1

Differential Apoptosis-Inducing Effect of Quercetin and its Glycosides in Human Promyeloleukemic HL-60 Cells by Alternative activation of Caspase 3 Cascade

Differential Apoptosis-Inducing Effect of Quercetin and its Glycosides in Human Promyeloleukemic HL-60 Cells by Alternative activation of Caspase 3 Cascade

... effect of glycosylation on their biological functions is still undefined. In the present study, the apoptosis-inducing activities of three structure-related flavonoids including aglycone ... See full document

2

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