[PDF] Top 20 BMP-7 Enhances Cell Migration and αvβ3 Integrin Expression via a c-Src-Dependent Pathway in Human Chondrosarcoma Cells
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BMP-7 Enhances Cell Migration and αvβ3 Integrin Expression via a c-Src-Dependent Pathway in Human Chondrosarcoma Cells
... is a member of the transforming growth factor (TGF)-beta superfamily, which is originally identified based on its ability to induce cartilage and bone ...formation. In recent years, ... See full document
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BMP-7 promotes αvβ3 integrin expression and cell motility through c-Src, PI3K/Akt, and NF-kB signaling pathway in human chondrosarcoma
... Taiwan 3 Department of Pharmacology, School of Medicine, China Medical University, Taichung, Taiwan Background: Bone morphogenetic protein 7 (BMP-7) encoded in a member of the ... See full document
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Macrophage migration inhibitory factor up-regulates αVβ3 integrin expression and cell migration via PI3K, Akt and NF-kB-dependent pathway in human chondrosarcoma cells
... INTRODUCTION: Chondrosarcoma is a malignant cancer that results in abnormal bone and cartilage ...is a skeletal tumor with various grades of malignancy, rapidly evolving, and ... See full document
1
Macrophage migration inhibitory factor increases cell motility and up-regulates αvβ3 integrin in human chondrosarcoma cells
... metastasis via signal-transduction pathways that converge to activate NF-B complex of transcription factors [Sliva, ...PI3K/Akt pathway is a major cascade mediating activation of the NF-B ... See full document
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HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells
... ABSTRACT Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...is a widely studied, ubiquitous nuclear protein that is present ... See full document
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TNF-a Increases avb3 Integrin Expression and Migration in Human Chondrosarcoma Cells
... -mediated migration activity and integrin ...role in the expression of integrin and migration of human chondrosarcoma ...B a c t i va t ... See full document
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CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrin-dependent pathway
... the migration assay, cells were pretreated for 30 min with inhibitors including Ly294002, wortmannin, Akt inhibitor, PDTC, TPCK, or vehicle control ...affect cell death of JJ012 cells, as ... See full document
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HGF increases migration and MMP-2 expression via PI3K, AKT and NF-kappaB dependent pathway in human chondrosarcoma cells
... INTRODUCTION: Chondrosarcoma is characterized by a high malignant and metastatic ...motility and promote invasion of tumor ...on migration activity in human ... See full document
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Bradykinin enhances cell migration in human prostate cancer cells through B2 receptor/PKC delta/c-Src dependent signaling pathway
... is a complex and multi-stage process in which secondary tumors are formed in distant sites ...transformation and tumor growth, angiogenesis, and lymphangiogenesis, entry of ... See full document
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BDNF increases human chondrosarcoma cells migration and b5 integrin expression via TrkB, PI3K/Akt and NF-kB dependent pathways
... is a Small-molecule protein from the "neurotrophin" family of growth ...found in the brain and the ...play a key role in metastasis of tumor ...on migration activity in ... See full document
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IL-8 increases integrin expression and cell motility in human chondrosarcoma cells
... Heyder C, Gloria-Maercker E, Hatzmann W, Niggemann B, Zanker KS, Dittmar ...subunit in the adhesion, extravasation and migration of T24 human bladder carcinoma ...phosphatidylinositol ... See full document
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CCN6 enhances ICAM-1 expression and cell motility in human chondrosarcoma cells
... chondrosarcoma cells. The AP-1 sequence binds to members of the Jun and Fos families of transcription ...induced c-Jun phosphorylation. In addition, c-Jun siRNA abolished the ... See full document
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Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.
... Abstract Chondrosarcoma is a malignant tumor that produces cartilage ...upregulated in highly aggressive ...suppressed cell migration. Exogenous AR markedly increased cell ... See full document
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CCL2 increases migration and MMP-9 expression via CCR2 receptor, Ras, Raf, MEK, ERK and NF-κB-dependent pathway in human chondrosarcoma cells
... INTRODUCTION: Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...tumor and accounts for about 25% of all malignant bone ... See full document
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WISP-1 increases MMP-2 expression and cell motility in human chondrosarcoma cells
... mAb and FAK(Y397F) mutant, indicating that the a 5 b 1 integrin and FAK occur as the upstream molecules involved in WISP-1-induced activation of ...with chondrosarcoma distant ... See full document
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CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-κB signaling pathway
... Abstract Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...metastasis. Chondrosarcoma shows a predilection for ... See full document
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IGF-I enhances α5β1 integrin expression and cell motility in human chondrosarcoma cells.
... of cells with Akt mutant reduced IGF-I-enhanced migration and integrin ...role in the expression of D5E1 integrin and migration of human ... See full document
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Amphiregulin increases a6b1 integrin expression and cell migration through Ras, Raf, MEK, ERK, c-Jun in human chondrosarcoma cells
... 中國醫藥大學基礎醫學研究所 3 中國醫藥大學醫學系藥理科 1 Department of Pharmacy, China Medical University, Taichung, Taiwan 2 Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan 3 Department of ... See full document
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瘦體素在人類前列腺癌細胞調節細胞移動及αvβ3 Integrin表現的探討; Leptin Mediates Cell Migration and αvβ3 Integrin Up-regulation in Human Prostate Cancer Cells
... (collagens)上，也能當作細胞與細胞間的黏著分子。 1. 高解析結構 雖然目前已有許多研究，但 integrins 高解析的結構對科學家們仍 是一種挑戰：膜蛋白基本上很難被單獨純化出來，而且 integrins 為巨 大、複雜並高醣基化的物質。低解析度的 integrins 影像可以由電子顯 微鏡獲得；也可由間接的方式：例如利用超高離心及放射光來調查 integrins 溶液的性質，可得到片段的高解析結晶結構；使用核磁共振 ... See full document
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Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells
... malignancy and elevated death rates from various cancers [35, ...High-level expression of leptin is observed in obese humans as well as in genetic and environmentally induced forms of ... See full document
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