[PDF] Top 20 IL-6 Increases MMP-13 Expression and Motility in Human Chondrosarcoma Cells
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IL-6 Increases MMP-13 Expression and Motility in Human Chondrosarcoma Cells
... locally and cause distant metastasis. Chondrosarcoma shows a predilection for metastasis to the ...lungs. IL-6 is a multifunctional cytokine that is associated with the disease status ... See full document
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IGF-I enhances α5β1 integrin expression and cell motility in human chondrosarcoma cells.
... integrin and activation of IGF-IR, PI3K, Akt, and NF-NB ...2009). Human cancer cells express IGF-IR (Gualberto and Karp, 2009); in addition, IGF-IR is involved in ... See full document
26
IL-8 increases integrin expression and cell motility in human chondrosarcoma cells
... subunit in the adhesion, extravasation and migration of T24 human bladder carcinoma ...factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine ... See full document
19
WISP-1 increases MMP-2 expression and cell motility in human chondrosarcoma cells
... mAb and FAK(Y397F) mutant, indicating that the a 5 b 1 integrin and FAK occur as the upstream molecules involved in WISP-1-induced activation of ...with chondrosarcoma distant metastasis is ... See full document
10
CCL2 increases MMP-9 expression and cell motility in human chondrosarcoma cells via the Ras/Raf/MEK/ERK/NF-κB signaling pathway
... Abstract Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...metastasis. Chondrosarcoma shows a predilection for metastasis to the ... See full document
23
Interleukin-11 Increases Cell Motility and Up-Regulates Intercellular Adhesion Molecule-1 Expression in Human Chondrosarcoma Cells
... osteosarcoma and Ewing’s sarcoma, which cause dramatic increases in long-term survival with the advent of systemic chemotherapy, chondrosarcoma continues to have a poor prognosis due to ... See full document
22
CCN6 enhances ICAM-1 expression and cell motility in human chondrosarcoma cells
... chondrosarcoma cells. The AP-1 sequence binds to members of the Jun and Fos families of transcription ...phosphorylation. In addition, c-Jun siRNA abolished the CCN6-induced cell migration ... See full document
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HMGB-1 induces cell motility and α5β1 integrin expression in human chondrosarcoma cells
... ABSTRACT Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...present in eukaryotic cells, and plays a crucial role in ... See full document
22
Macrophage migration inhibitory factor increases cell motility and up-regulates αvβ3 integrin in human chondrosarcoma cells
... pathway in human cancer cells [Sliva, ...phosphorylation in human chondrosarcoma cells. Pretreatment of cells with PI3K inhibitors Ly294002 or wortmannin ... See full document
23
Amphiregulin enhances alpha6beta1 integrin expression and cell motility in human chondrosarcoma cells through Ras/Raf/MEK/ERK/AP-1 pathway.
... expressed in a variety of malignancies, insights into the mechanisms related to the anti-tumor activity of AR targeted therapy might help improve chondrosarcoma ...therapy. In chondrosarcoma, ... See full document
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CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrin-dependent pathway
... (Cyr61) and CCN2 (CTGF) modulates cell migration and invasion in human chondrosarcoma cells (Tan et ...activity in human chondrosarcoma cells is ... See full document
23
HGF increases migration and MMP-2 expression via PI3K, AKT and NF-kappaB dependent pathway in human chondrosarcoma cells
... INTRODUCTION: Chondrosarcoma is characterized by a high malignant and metastatic ...proliferation, motility and promote invasion of tumor ...activity in human ... See full document
1
Brain-derived neurotrophic factor increases vascular endothelial growth factor expression and enhances angiogenesis in human chondrosarcoma cells
... step in metastasis and a critical stage in cancer progression is the acquisition of motility by a tumor ...with chondrosarcoma . In addition, angiogenesis plays an important step ... See full document
28
BMP-7 promotes αvβ3 integrin expression and cell motility through c-Src, PI3K/Akt, and NF-kB signaling pathway in human chondrosarcoma
... encoded in a member of the TGF- β ...role in the transformation of mesenchymal cells into bone and ...activity in human chondrosarcoma cells is still ... See full document
1
Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells
... malignancy and elevated death rates from various cancers [35, ...High-level expression of leptin is observed in obese humans as well as in genetic and environmentally induced forms of ... See full document
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Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells
... Leptin increases VEGF expression and enhances angiogenesis in human chondrosarcoma cells Yi-Chin Fong 1,2* ,Wei-Hung Yang 3,4,5,6 , Jui-Chieh Chen 7,8 , Chih-Hsin Tang ... See full document
1
IL-6 promotes ICAM-1 expression and cell motility in human osteosarcoma
... up-regulated in response to a variety of cytokines and is associated with inflammatory and immune responses ...evidence in this study show that, in addition to its role in ... See full document
24
TNF-a Increases avb3 Integrin Expression and Migration in Human Chondrosarcoma Cells
... activity and integrin ...role in the expression of integrin and migration of human chondrosarcoma ...suggested, and all of them rely on sequentially activated kinase ...as ... See full document
22
CCL2 increases migration and MMP-9 expression via CCR2 receptor, Ras, Raf, MEK, ERK and NF-κB-dependent pathway in human chondrosarcoma cells
... INTRODUCTION: Chondrosarcoma is a type of highly malignant tumor with a potent capacity to invade locally and cause distant ...tumor and accounts for about 25% of all malignant bone ...commonly ... See full document
1
Cyr61 increases matrix metalloproteinase-3 expression and cell motility in human oral squamous cell carcinoma cells
... cancer cells in recent years has identified various molecular pathways that are altered in different ...molecules in these pathways. To achieve metastasis, cancer cells must evade ... See full document
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