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[PDF] Top 20 Sodium selenite inhibits γ-secretase activity through activation of ERK

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Sodium selenite inhibits γ-secretase activity through activation of ERK

Sodium selenite inhibits γ-secretase activity through activation of ERK

... alignment of external optical components to the chip has to be as pre- cise as ...normal of vertical micromirrors is uniform because it is aligned to the silicon crystal orien- ...effects of angular ... See full document

3

Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells

Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells

... both of the phospho-ERK and phospho-JNK were induced by HBO in 15 min of HBO ...signal of JNK activation, phospho-c-Jun, and found that the phosho-c-Jun was also induced in 1 h ... See full document

14

Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells

Hyperbaric oxygen induces VEGF expression through ERK, JNK and c-Jun/AP-1 activation in human umbilical vein endothelial cells

... activated through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) and extracellular signal regulated kinase (ERK), we further examined the c-Jun, JNK and ERK that might be involved ... See full document

2

Activation of the ERK signal transduction pathway by Epstein–Barr virus immediate-early protein Rta

Activation of the ERK signal transduction pathway by Epstein–Barr virus immediate-early protein Rta

... capacity of Rta to activate the mutant BZLF1 promoter without these sites (pNS3) was reduce substantially ...via activation of the ERK signal transduction ...and activation via these ... See full document

10

Ovariectomy affects activation of ERK and pain hypersensitivity in acid injection-induced widespread muscle pain

Ovariectomy affects activation of ERK and pain hypersensitivity in acid injection-induced widespread muscle pain

... pathway of the neurotrophic effect of tianeptine on the structural plasticity was studied by evaluation of the possible kinases phosphorylation after ... See full document

1

PKC- and ERK-dependent activation of IkB kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activation.

PKC- and ERK-dependent activation of IkB kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activation.

... B activity in response to several cytokines, the upstream kinases that control IKK activity are still not completely ...receptor activation by UTP potentiates lipopolysaccharide (LPS)-induced I kappa ... See full document

1

EPOX Inhibits Angiogenesis by Degradation of Mcl-1 through ERK Inactivation

EPOX Inhibits Angiogenesis by Degradation of Mcl-1 through ERK Inactivation

... Results: EPOX induced endothelial cell apoptosis in association with proteasome-dependent Mcl-1 degradation. Down-regulation of Mcl-1 resulted in an increase in Mcl-1-free Bim, activation of Bax, and ... See full document

3

The extract of Rhodobacter sphaeroides inhibits melanogenesis through the MEK/ERK signaling pathway

The extract of Rhodobacter sphaeroides inhibits melanogenesis through the MEK/ERK signaling pathway

... to ERK signaling ...suppressed activation of cAMP response element-binding protein (CREB) via the down-regulation of p38 had been reported in hypopigmentation ... See full document

8

Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis

Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis

... one of the most common malignancies worldwide, and the main cause of cancer-related 28 death in ...effects of euphol, a triterpene alcohol with anti- 29 inflammatory and antiviral activities on human ... See full document

7

Quantitative phosphoproteomic analysis reveals γ-bisabolene inducing p53-mediated apoptosis of human oral squamous cell carcinoma via HDAC2 inhibition and ERK1/2 activation

Quantitative phosphoproteomic analysis reveals γ-bisabolene inducing p53-mediated apoptosis of human oral squamous cell carcinoma via HDAC2 inhibition and ERK1/2 activation

... Abstract γ-Bisabolene, one of main components in cardamom, showed potent in vitro and in vivo antiproliferative activities against human oral squamous cell carcinoma ...(OSCC). γ-Bisabolene activated ... See full document

42

[6]-Shogaol Inhibits ?-MSH-Induced Melanogenesis through the Acceleration of ERK and PI3K/Akt-Mediated MITF Degradation

[6]-Shogaol Inhibits ?-MSH-Induced Melanogenesis through the Acceleration of ERK and PI3K/Akt-Mediated MITF Degradation

... mechanisms of [6]-shogaol on melanin synthesis. The biosynthesis of melanin is a complicated process involving many ...the activation of adenylyl cyclase, followed by cAMP production ... See full document

16

Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMPK

Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMPK

... Confidential - ACS AMPK P-AMPK Hispidulin Hispidulin Growth arrest Apoptosis mTOR Protein synthesis ACC FASN. Fatty acid synthe sis Figure 8.[r] ... See full document

41

The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.

The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.

... Furthermore, TMPZ concentration (50 and 200m M)- and time (15 and 30 min)-dependently triggered endothelial- type constitutive nitric oxide synthase (ecNOS) protein expr[r] ... See full document

1

The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.

The antiplatelet activity of tetramethylpyrazine is mediated through activation of NO synthase.

... Furthermore, TMPZ concentration (50 and 200m M)- and time (15 and 30 min)-dependently triggered endothelial- type constitutive nitric oxide synthase (ecNOS) protein expression in huma[r] ... See full document

1

Antiplatelet activity of nifedipine is mediated by inhibition of NF-κB activation caused by enhancement of PPAR-β/-γ activity

Antiplatelet activity of nifedipine is mediated by inhibition of NF-κB activation caused by enhancement of PPAR-β/-γ activity

... Ro106-9920 inhibits platelet aggregation via suppressing the PLA 2 -TxA 2 cascade and surface GPIIb/IIIa expression (Malaver et ...NF-κB activation may exhibit antiplatelet ...NF-κB activation in ... See full document

1

Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways

Taiwanin A inhibits MCF-7 cancer cell activity through induction of oxidative stress, upregulation of DNA damage checkpoint kinases, and activation of p53 and FasL/Fas signaling pathways

... number of potential molecular targets for novel anticancer drug discovery have been identified in cell-cycle or apoptosis mech- ...product of a tumor suppressor gene, plays a major role in protecting mammals ... See full document

9

Competitive adsorption of molybdate, chromate, sulfate, selenate, and selenite on γ-Al2O3

Competitive adsorption of molybdate, chromate, sulfate, selenate, and selenite on γ-Al2O3

... most of the previous studies, influence of competitive adsorption on anion partitioning has been addressed in binary-solute systems contain- ing strongly binding anion with organic com- pound or sulfate ... See full document

9

Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB.

Propofol inhibits lipoteichoic acid-induced iNOS gene expression in macrophages possibly through downregulation of toll-like receptor 2-mediated activation of Raf-MEK1/2-ERK1/2-IKK-NFκB.

... component of Gram-positive bacteria, can induce septic ...effects of propofol on LTA-induced iNOS gene expression in macrophages and its possible molecular ...Exposure of macrophages to LTA increased ... See full document

1

A cyclohexadepsipeptide from entomogenous fungi Metarhizium anisopliae inhibits the Helicobacter pylori induced pathogenesis through attenuation of vacuolating cytotoxin-A activity

A cyclohexadepsipeptide from entomogenous fungi Metarhizium anisopliae inhibits the Helicobacter pylori induced pathogenesis through attenuation of vacuolating cytotoxin-A activity

... inhibitor of V-ATPase and VacA-mediated ...inhibition of VacA-actions by Dtx-B may modulate the development of gastric cancer induced by ...vacuolization of gastric epithelial ...pathogenesis ... See full document

1

Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8/caspase-3 dependent pathway

Fisetin induces apoptosis in human cervical cancer HeLa cells through ERK1/2-mediated activation of caspase-8/caspase-3 dependent pathway

... effects of fisetin on the induction of apoptosis in human cervical cancer HeLa cells were never investigated and ...apoptosis of HeLa cells in a dose- and time-dependent manner, as evidenced by ... See full document

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