• 沒有找到結果。

第五章 結論與未來展望

材料降解的情形仍然發生,尤其於樣品配方比(PEGDA:P407DA:mPDMS )8:1:1 之 水膠在第二個月時有被大鼠組織吸收的情況產生,而第三個月所有製成之樣品水

體製成之水膠的效果較好,此外雖大部分的性質有所改善,但於動物實驗之中對 照 PEGDA 水膠卻仍舊沒有細胞長入水膠,此結果應為水膠材料的特性所致。

目前由 FDA 所通過之人工角膜,以剛性合成材料(波士頓人工角膜,Boston Kpro)及軟性合成水膠(AlphaCor)為主,並由臨床研究及個案報告之結果比較,以 剛性合成材料的成果較佳而軟性的合成水膠較差,因此在本研究中,吾人使用不 同的材料及配方,以較為簡單且低溫之光交聯方法合成水膠,以期開發能夠大量 生產的角膜襯裙材料,供軟性水膠製成之人工角膜的改善使用。

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