對於過敏性鼻炎臨床症狀的表現，可以陰陽之差、氣血之和、
性別、年齡、病程、IgE、ECP 等七個自變數來解釋其嚴重度；並可 依陰陽之差、氣血之和將過敏症狀區分為兩群；並可依陰陽之差、
氣血之和將過敏症狀區分為兩群；性別、病程、陰陽之差、氣血之 和同時可能干擾IgE、ECP 與過敏性鼻炎臨床症狀的相關性。
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The Study of the Relationship between the Clinical Manifestation of Allergic Rhinitis and the Yin,Yan,Qi,Blood
Variables in Chinese medical Constitutional Status
Chia-Lin Lee
Major Professor: Yi-chang, Su
Institute of Chinese Medical Science, China Medical University
Abstract
The prevalence of allergic rhinitis is increasing in Taiwan. Many people concurrently seek for the help of Chinese medicine and modern medicine.
An important issue has emerged of whether combining the study effort of Chinese medicine and modern medicine can improve our understanding to the disease.
This study was exploratory, cross-sectional, and correlative. One hundred and nineteen patients were recruited. The following data were recorded: demographic information of patients, symptom scores of rhinitis, physical evaluation of rhinitis, inflammation mediators, the Chinese medical constitutional parameters of yin, yan, qi, and blood. Multiple linear
regression and logistic regression models were used to evaluate factors regarding allergic rhinitis in Chinese medicine and modern medicine.
Seven independent factors were used to predict the severity of allergic
rhinitis. These factors were: “score of Yin minus Yang”, “score of Qi plus Blood”, gender, age, duration of allergic rhinitis, IgE, and ECP. The five major symptoms of allergic rhinitis could be divided into two subgroups by
“score of Yin minus Yang” and “score of Qi plus Blood”. One subgroup included sneezing, rhinorrhea, nasal itching, eye itching, and the other subgroup included nasal blockage. After adjusting the confounding effect of gender, duration of allergic rhinitis and Chinese medical constitutional status, the association between inflammation mediators and the severity of allergic rhinitis would then become statistically significant. This demonstrated that it would be more accurate to evaluate the severity by taking Chinese medical constitutional status into account.
Key words: Chinese medicine; constitution; allergic rhinitis; yin, yan, qi, blood; regression analysis
謝辭
當一個好的科學家，是我我從小的憧憬，大學聯考後，卻在懵懵懂 懂、因緣際會下，闖進了醫學的領域，在眾多醫學名詞的背誦中，逐漸 喪失了對未知世界探索的熱情，ㄧ度以為要在病人群裡終老ㄧ生，沮喪 萬分。然而，intern 時期，感謝外科王惠暢主任的ㄧ句「always be curious」，終於點燃了心裡頭沉睡已久的夢想，決定給自己一個機會放 手去做，全力奔馳的機會，當不成頂尖的科學家，至少曾經呼吸過科學 聖殿裡的空氣吧!我是這麼想的，就這樣栽進了兩年的研究生涯。
完成論文的此時，必須先感謝父母親的支持，在家中經濟不充裕的 情況下，還願意讓我安心的讀完兩年書，我很感恩；也感謝指導教授-蘇奕彰博士，在兩年的研究生活中，給我充分的自由，能讓我盡情的學 習我想學的，悠遊在中國與逢甲各系所，吸收各方新知，著實讓我感受 到學問的樂趣；更感謝李采娟老師的耐心，幫我建構完整的統計概念基 礎，使我在複雜的統計叢林中，不至於迷失了方向。
在研究執行的過程中，要特別感謝中榮耳鼻喉科江榮山主任、梁凱 莉大夫、以及可愛的雅惠小姐，因為有你們的大力幫忙，才能讓一個研 究菜鳥得以跌跌撞撞的完成本研究。
在此，誠摯的表示我深深的感激，謝謝大家。