針刺左手外關穴得氣在針刺期即降低左手背中央部位皮膚血流；針 刺左手外關穴未得氣則至針刺後期才有皮膚血流降低的反應。而針刺右 手外關穴則沒有相似結果，說明針刺需得氣才能得到更好的作用，以及 針刺作用生理機制中神經節段的反應扮演重要的角色。針刺對CGRP的 關係有待進一步研究。
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附錄
Abstract
In order to investigate the effect of acupuncture stimulation (AS) on skin blood flow and the relationship to calcitonin-gene related peptide（
CGRP）. A total of 17 healthy adults were studied, and all of them accepted to three assessments as follows : 1) Left Waiguan (SJ5) group (LW), AS applied to Waiguan acupoint of left hand with Der Qi; 2) Right Waiguan group (RW), AS applied to Waiguan acupoint of right hand with Der Qi; 3) Sham acupuncture group (SA), AS applied to the cutaneous region located Waiguan acupoint of left hand, but without Der Qi. Each assessment divided into pre-acupuncture period (BP), acupuncture period (AP) and post-acupuncture period (PP). Skin blood flow was recorded for 20 minutes at central dorsal part of left hand in each period. Besides, blood levels of calcitonin-gene related peptide (CGRP) were measured before AS, and finish of AP recordings immediately. Results indicated that the skin blood flow decreased in AP and PP than BP in the LW; whereas skin blood flow was similar between BP and AP. The results also indicated that the skin blood flow decreased in PP than BP in the SA; the skin blood flow was not changes among BP, AP and PP in the RW. AS at left Waiguan acupoint could not change the blood levels of CGRP.
AS applied to left Waiguan acupoint decreased the skin blood flow of central dorsal part of left hand, whereas AS at right Waiguan acupoint can not obtain similar results, suggesting that Der Qi in the AS may produce more stronger physiological effect, and nerve segmental effect plays an important role in physiological mechanism of AS. As regard to the relationship between AS and CGRP needs further study.
Keywords：Acupuncture, Waiguan acupoint (SJ5), skin blood flow,
calcitonin-gene related peptide謝辭
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詹雅閔 謹誌 中西醫結合研究所 2007 夏