結論

黃芩 Butanol、EtOAc 粗萃物和化合物 oroxylin A、wogonin、

7-O-methylwogonin、skullcapflavone II、5,7, 4'-trihydroxy-8-methoxyflavone、

5,6,2'-trihydroxy-7,8-dimethoxyflavone 和 ganhuangenin 在 P. acnes 誘導 in vitro 和 in vivo 模式中，皆有顯著抑制抗發炎的效果。

以 heat-killed P. acnes 誘導 THP-1 細胞生成促發炎激素模式中，wogonin 和 5,6'-dihydroxy-6,7,8,2' –tetramethoxyflavone 具有最佳的抗發炎效果，而以 P. acnes 引起小鼠耳朵腫脹與發炎模式中，七個黃酮類化合物區分不出那一個有最佳效 果。

結果顯示黃芩粗萃物和其中分離之黃酮類化合物皆具良好抗發炎效果，未來 可以進一步了解相關機制，發展成為改善痤瘡的藥物。

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在文檔中 黃芩萃取物及其組成分抑制痤瘡丙酸桿菌誘導之發炎反應 (頁 75-85)