結論

本實驗的結果，可以歸納出以下幾點：

１． 當使用 4-META/MMA-TBB 將金屬矯正器黏著於金屬假牙上 時，Ni-Cr alloy 假牙的黏著強度，比 Au-Pt alloy 假牙來 得高。

２． 使用 V-primer 能有效的增加 4-META/MMA-TBB 與 Au-Pt alloy 假牙的黏著強度。

３． 對於 Ni-Cr alloy 假牙而言，無論是否使用 V-primer，對 於其與 4-META/MMA-TBB 的黏著強度均無差異。

４． V-primer 的使用，無論在尚未揮發或是揮發至乾燥的情況 下再行使用樹脂黏著，皆不影響黏著強度的表現。

５． 37 度水浴 24 小時後，黏著強度呈現顯著的降低。

第六章 未來展望

臨床上經常發生矯正器與金屬假牙黏著強度不足的現象，造 成醫病雙方的困擾，本實驗試著找出不同金屬合金與使用

V-primer 的黏著強度之差異，但實驗結果顯示黏著強度仍需要提 高才能更符合臨床使用，雖然以往的文獻已告訴我們數種表面處 理方式（Silica coating、tin-plating、ion-coating 等等）能 獲得臨床上足夠使用的黏著強度，但是於臨床操作上皆不如 V-primer 的使用來得簡便，因此未來希望能找出改良的方式，或 是找出不同的處理方式來增進 V-primer 的效用，以期解決臨床操 作的難題。

參考文獻

1 Hotta K, Mogi M, Miura F, Nakabayashi N. Effect of 4-MET on bond strength and penetration of monomers into enamel. Dental Material, 1992 May;8(3):173-5.

２ Petra Schmage, Ibrahim Nergiz, Wolfram Herrmann, Mutlu O¨ zcan. Influence of various surface-conditioning methods on the bond strength of metal brackets to ceramic surfaces. American Journal of Orthodontics and Dentofacial Orthopedics, 2003;123:540-6.

３Ping-Ting Chen, Chen-Sheng Chen, Yih-Wen Gung. Failure analysis of enamel after removing orthodontic bracket. National Yang-Ming University, Institute of Rehabilitation Science and Technology, Master Thesis.

4 Mandall NA, Hickman J, Macfarlane TTV, Mattick RCR, Millett DT, Worthington HV. Adhesives for fixed orthodontic brackets (Review). The Cochrane Library 2007, Issue 1

５Nobuo Nakabayashi. Adhesive Bonding with 4-META. Operative Dentistry, 1992, 125~130

６Chang JC, Hurst TL, Hart DA, Estey AW. 4-META use in dentistry: A literature review. The Journal of Prosthetic Dentistry, 2002; 87:216~24

７S. A. Clark, P. H. Gordon and J. F. McCabe. An ex vivo investigation to compare orthodontic bonding using a 4-META-based adhesive or a composite adhesive to acid-etched and sandblasted enamel. Journal of Orthodontics, 2003;30:51–58.

８許智淵, 劉英麟. The reactivities of nanoscale colloidal silica toward epoxy compounds and their applications. 私立中原大學,化學工程學系,碩士學位論文

９Saito K, Sirirungrojying S, Meguro D, Hayakawa T, Kasai K. Bonding Durability of Using Self-Etching Primer with 4-META/MMA-TBB Resin Cement to Bond Orthodontic Brackets. The Angle Orthodontist. 2005 Mar;75(2):260-5

１０John W. Nicholson. Adhesive dental materials and their durability. International Journal of Adhesion & Adhesives 20 (2000) 11}16

１１Robert P. Kusy. Orthodontic Biomaterials: From the Past to the Present. Angle Orthodontist, 2002 Dec;72(6):501-12.

１２Faust JB, Grego GN, Fan PL, Powers JM. Penetration coefficient, tensile strength, and bond strength of thirteen direct bonding orthodontic cements. American journal of orthodontics, 1978 May;73(5):512-25.

１３Brantley WA, Eliades T. Orthodontic materials: Scientific and clinical aspects, Thieme, New York, pp.190-191, 2001.

１４Conservative Operative Dentistry. Lecture: Bonding Systems (Enamel, Dentin, Compomer, Amalgam, Resin Cement). 2005-2006, Stephen C. Bayne, Chapel Hill, NC 27514.

１５Gottfried Schmalz, Pauline Garhammer. Biological interactions of dental cast alloys with oral tissues. Dental materials, 18(2002)396-406

16James C. Setcos, Amir Babaei-Mahani, Lucy Di Silvio, Ivar A. Mjor, Nairn H.F.

Wilson. The safety of nickel containing dental alloys. Dental materials, 22(2006)1163-1168

17Kojima K, Kadoma Y, Imai Y. Adhesion to precious metals utilizing triazine dithione derivative monomer. Journal of Japan Dental Materials, 1987;6:702-7

18Kojima K, Kadoma Y, Yamauchi J. Study on adhesive primer to dental metal used for composite type resin cement. Journal of Japan Dental Materials, 1997;16:316-21

19M. Suzuki, A. Fujishima, T. Miyazaki, H. Hisamitsu, K. Kojima, Y. Kadoma. A study on the adsorption structure of an adhesive monomer for precious metals by surface-enhanced Raman scattering spectroscopy. Biomaterials, 20(1999)839-845

20Mizuno A, Toda Y, Itoh M, Kojima K, Kadoma Y. NMR analysis of

tautomerization of triazine derivative in solid and acetone solution. Jourmal of Molecular Structure, 1998;441:149-153

21Bryant MA, Pemberton JE. Surface Raman scattering of self-assembled monolayers formed from 1-alkanethiols

22Zachrisson BU, Buyukyilmaz T. Recent advances in bonding to gold, amalgam and porcelain. Journal of Clinical Orthodontics. 1993;27:661-675

23Eames WB, Rogers LB, Feller PR, Price WR. Bonding agents for repairing porcelain and gold. American Journal of Orthodontics Dentofacial Orthopedics, 1977;2:118-21

24Andreasen GF, Stieg MA. Bonding and debonding brackets to porcelain and gold.

American Journal of Orthodontics Dentofacial Orthopedics, 1988;93:341-5

25Diaz-Arnold AM, Wistrom DW, Aquilino SA, Swift EJ. Bond strengths of porcelain repair adhesive systems. American Journal of Orthodontics Dentofacial Orthopedics, 1993;6:291-4

26Kocadereli I, Canay S, Akca K. Tensile bond strength of ceramic orthodontic brackets bonded to porcelain surfaces. American Journal of Orthodontics Dentofacial Orthopedics, 2001;119:617-20.

27Zachrisson YØ, Zachrisson BU, Bu¨yu¨kyilmaz T. Surface preparation for orthodontic bonding to porcelain. American Journal of Orthodontics Dentofacial Orthopedics ,1996;109:420-30.

28 Akin-Nergiz N, Nergiz I, Behlfeld K, Platzer U. Shear bond strength of a new polycarbonate bracket—an in vitro study with 14 adhesives. European Journal of Orthodontics, 1996;18:295-301

29Eustaquio R, Garner LD, Moore BK. Comparative tensile strengths of brackets bonded to porcelain with orthodontic adhesive and porcelain repair systems.

American Journal of Orthodontics Dentofacial Orthopedics, 1988;94:421-5.

30Smith GA, McInnes-Ledoux P, Ledoux WR, Weinberg R. Orthodontic bonding to

porcelain—bond strength and refinishing. American Journal of Orthodontics Dentofacial Orthopedics, 1988;94:245-52.

31Wood DJ, Bubb NL, Millar BJ, Dunne SM. Preliminary investigation of a novel retentive system for hydrofluoric acid etchresistant dental ceramics. Journal of Prosthetic Dentistry, 1997;78:275-80.

32Peterson IM, Pajares A, Lawn BR, Thompson VP, Rekow ED. Mechanical

characterization of dental ceramics by Hertzian contacts. Journal of Dental Research, 1998;77:589-602

33Nebbe B, Stein E. Orthodontic brackets bonded to glazed and deglazed porcelain surfaces. American Journal of Orthodontics Dentofacial Orthopedics,

1996;109:431-6.

34Chung KH, Hwang YC. Bonding strengths of porcelain repair systems with various surface treatments. Journal of Prosthetic Dentistry, 1997; 78:267-74.

35Sorensen JA, Kang SK, Avera SP. Porcelain-composite interface microleakage with various porcelain surface treatments. Dental Materials 1991;7:118-23.

36Tylka DF, Stewart GP. Comparison of acidulated phosphate fluoride gel and hydrofluoric acid etchants for porcelain-composite repair. Journal of Prosthetic Dentistry 1994;72:121-7.

37 Gloria Nollie.Timothy F. F.Orthodontic bonding to Adlloy-treated type IV gold.

Angle Orthodontics 1997;67(3) 183-188

38 T. Tanaka, M. Hirano, M. Kawahara, H. Matsumura, M. Atsuta, A New Ion-coating Surface Treatment of Alloys for Dental Adhesive Resins. Journal of Dental Research, 1988;67(11):1376-1380

39 Watanabe, F.; Powers, J.M.; and Lorey, R.E.: In vitro Bonding of Prosthodontic Adhesives to Dental Alloys, Journal of Dental Research, 1988;67:479-483.

40 Yoshida, K., Kamada, K., Tanagawa, M. & Atsuta, M. Shear bond strengths of three resin cements used with three adhesive primers for metal. Journal of Prosthetic Dentistry, 1996;75:254.

41 Lin TH, Chang HJ, Chung KH: Interfacial strengths of various alloy surface treatments for resin-bonded fixed partial dentures. Journal of Prosthetic Dentistry 1990;64:158-162

42El-Sherif MH, El-Messery A, Halhoul MN: The effects of alloy surface treatments and resins on the retention of resin-bonded retainers. Journal of Prosthetic Dentistry, 1991;65:782-786

43Watanabe F, Powers JM, Lorey RE: In vitro bonding of prosthodontic adhesives to dental alloys. Journal of Dental Research,1988; 67:479-483

44 Rubo JH, Pegoraro LF, Ferreira PM: A comparison of tensile bond strengths of resin-retained prostheses made using five alloys. International Journal of

Prosthodontics,1996;9:277-281

45Darunee P. NaBadalung, John M. Powers, Mark E. Connelly. Comparison of bond strengths of denture base resins to nickel-chromiumberyllium removable partial denture alloy. Journal of Prosthetic Dentistry;1997;78:566-73

46 T. Tanaka,K. Nagata,M. Takeyama,M. Atsuta,N. Nakabayashi,E. Masuhara, 4-META Opaque Resin-A New Resin Strongly Adhesive to Nickel-Chromium Alloy.

Journal of Dental Research, 1981;60(9):1697-1706

47Tanaka, T., Atsuta, M., Nakabayashi, N. & Masuhara, E. Surface treatment of gold alloys for adhesion. Journal of Prosthetic Dentistry, 1988;60:271

48

Ana M. Diaz-Arnold , John C. Keller, James P. Wightman, Vincent D. Williams,

Bond strength and surface characterization of Ni-Cr-Be alloy, Dental Materials,1996;12:58-63

49 Cognard, J. Quantitative measurement of the energy of fracture of an adhesive joint using the wedge-test. Journal of Adhesion, 1987;22:97.

50White SN, Yu Z. Physical properties of fixed prosthodontics, resin composite luting agents lnternational Journal of Prosthodontics, 1993;6:384-389.

51Yasuda, N.; Sasaki, M.; Mogi, T.,Ai, M., Nakabayashi, N. Interface Between Metal and Resin on the Finishing Line of Co-Cr Denture. Journal of Japan Prosthetic Dentistry, 1978;22:525

52P. Moulin, M. Degrange B. Picard, Ingluence of surface treatment on adherence energy of alloys used in bonded prosthetics. Journal of Oral Rehabilitaton,

1999;26:413-421

53Tanaka T, Fujiyama E, Shemey H, Takaki A, Atsula M. Surface treatment of nonprecious alloys for adhesion fixed partial denture. Journal of Prosthetic Dentistry, 1986;55:456-62.

54Jacobson TE. The significance of adhesive denture base resin. International Journal of Prosthodontics, 1989;2:163-72.

55Hamada T, Shigato N, Yanagihara T. A decade of progress of the adhesive fixed partial denture. Journal of Prosthetic Dentistry, 1985;54:24-9.

56Rochette AL. Attachment of a splint to enamel of lower anterior teeth. Journal of Prosthetic Dentistry, 1973;30:418-23

57 K. Yoshida, K. Kamada, Y. Taira, M. Atsuta. Effect of three adhesive primers on the bond strengths of four light-activated opaque resins to noble alloy. Journal of Oral Rehabilitation, 2001;28:168-173

５８Chamda RA, Stein E. Time-related bond strengths of light-cured and chemically cured bonding systems: An in vitro study. American Journal of Orthodontics and Dentofacial Orthopedics. 1996;110:378-82

５９Paul W. Major, James R. Koehler, Kieth E. Manning 24-hour shear bond strength

of metal orthodontic brackets bonded to porcelain using various adhesion promoters.

American Journal of Orthodontics Dentofacial Orthopedics, 1995;108:322-9

60T. Tanaka, M. Hirano, M. Kawahara, H. Matsumura, and M. Atsuta A New Ion-coating Surface Treatment of Alloys for Dental Adhesive Resins Journal of Dental Research, 1988;67(11)1376-1380

61Hiroki Ohnoa,, Kazuhiko Endoa, Masanori Hashimoto New mechanical retention method for resin and gold alloy bonding Dental Materials, 2004;20:330-337

62 V.D. WILLIAMS1 and C.W. SVARE. The Effect of Five-year Storage Prior to Bonding on Enamel/Composite Bond Strength. Journal of Dental Research, 1985;

64(2):151-154.

63 Keiichi Yoshida, Kohji Kamada, Mika Tanagawa, Mitsuru Atsuta Shear bond strengths of three resin cements used with three adhesive primers for metal The Journal of Prosthetic Dentistry 1996;75:254-61

64 Arndt Klocke, Ba¨rbel Kahl-Nieke Influence of force location in orthodontic shear bond strength testing Dental Materials, 2005; 21:391–396

65 Arndt Klocke, Ba¨rbel Kahl-Nieke. Influence of cross-head speed in orthodontic bond strength testing. Dental Materials, 2005; 21:139–144.

６６T.K. Jones, C.A. Hansen, M.T. Singer, H.P. Kessler. Dental implications of nickel hypersensitivity Journal of Prosthetic Dentistry ,1986;56 :507–509.

67J.P. Moffa, A.D. Guckes, M.T. Okawa, G.E. Lilly An evaluation of nonprecious alloys for use with porcelain veneers. Part II. Industrial safety and biocompatibility Journal of Prosthetic Dentistry 1974; 30:432–441.

６８

K. Yoshida, M. Atsuta

69P.Moulin, B. Picard, M. Degrange Water resistance of resin-bonded joints with time related to alloy surface treatment Journal of Dentistry 1999;27:79-87

70C. W. Barclay, E. L. Boyle, R. Williams, P. M. Marquis The effect of

thermocycling on five adhesive luting cements Journal of Oral Rehabilitation, 2002;

29:546–552

作者簡歷

１． 姓名：賴怡妏 ２． 性別：女

３． 生日：民國６９年７月３日

４． 學歷：中山醫學大學牙醫系第４０屆（87.9~93.6）

中國醫藥大學醫學研究所牙醫學組（95.9~97.6）

５． 經歷：中國醫藥大學附設醫院住院醫師（93.7~94.6）